The Best Business Hotels in Muscatine, IA in 2026

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Our top choices for Muscatine business-friendly hotels

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Desk, iron/ironing board, WiFi (surcharge), alarm clocks

1. Best Western Muscatine / Pearl City Hotel

Muscatine

Debra

AED 346

AED 387 total

includes taxes & fees

10 Sep - 11 Sep

48-inch flat-screen TV with cable channels, TV

2. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

Muscatine

Cindy

AED 621

AED 695 total

includes taxes & fees

25 Sep - 26 Sep

Suite, 2 Queen Beds, Non Smoking (One-Bedroom) | Desk, blackout drapes, iron/ironing board, cribs (free)

3. AmericInn by Wyndham Muscatine

Muscatine

Larry

AED 328

AED 367 total

includes taxes & fees

20 Sep - 21 Sep

Room, 1 King Bed, Smoking | Desk, iron/ironing board (on request), cribs (free)

4. Days Inn by Wyndham Walcott Davenport

Walcott

Dianne

AED 203

AED 227 total

includes taxes & fees

25 Sep - 26 Sep

Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

5. Comfort Inn & Suites Davenport - Quad Cities

Davenport

Rada

AED 315

AED 353 total

includes taxes & fees

20 Sep - 21 Sep

6. Quality Inn & Suites Eldridge Davenport North

Eldridge

carey

AED 250

AED 280 total

includes taxes & fees

20 Sep - 21 Sep

North Executive Suite, 1 King, Non-Smoking | Premium bedding, pillowtop beds, in-room safe, desk

7. Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

Bettendorf

Kelly

AED 294

AED 387 total

includes taxes & fees

21 Sep - 22 Sep

3 restaurants; breakfast, lunch, and dinner served

8. Bally's Quad Cities

Rock Island

Glenda

AED 463

AED 567 total

includes taxes & fees

9 Sep - 10 Sep

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Top Muscatine Hotel Reviews

Stoney Creek Hotel Quad Cities - Moline

8/10 Good

"We have stayed at Stoney Creek in Moline many times over several years, and continue to love the proximity to the Mississippi River and the hotel's cabin vibe. But the property shows signs of wear: several pieces of furniture in our room were splintered/broken, the pool area's mural has leaked and been patched over time, the hot tub was broken, and the hallways could use vacuuming and more regular trash removal. The gym doesn't have yoga balls or free weights, which many other hotels do. It was great to see the koi ponds are newly tended. There just needs to be inventory taken of broken things in rooms, and replacements made. Would also be great if the hotel could enforce its no-smoking policy in the outdoor section of the restaurant: the ground was littered with cigarette butts."

Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

10/10 Excellent

"Front desk was so quick and friendly! Rooms in North side were so clean!"

DoubleTree by Hilton Davenport

8/10 Good

"Staff was very friendly and helpful. One downfall is we couldn’t check in until 5:00. Kids enjoyed the pool and breakfast. Rooms are spacious with great views. We also love the location."

AmericInn by Wyndham Muscatine

10/10 Excellent

"Everything was clean and as listed. Staff were friendly."

Hotel Blackhawk, Autograph Collection

8/10 Good

"Love that this hotel was dog friendly however, there is no grass anywhere close to the property and the area’s we were directed to were full of trash and unkept. 2 very small patches of grass on the property were also unkempt with in picked up feces. Our room had visible dust and cob webs in obvious places as well as small dead bugs on most window ledges. I love the room set up. We booked the room for 3 adults but when we arrived there were amenities for two people . The sofa bed was not ready to use and we had to call for sheets when we got back late and had to make up the bed ourself. They seemed to be really short on staff at their restaurant I had to wait 10 minutes as the waitress told me she couldn’t help me as she was busy. I went to the indoor pool and the humidity and heat were so high I had to leave. The pool water was very hot and not usable. Pool also looks like it needs an update."

Comfort Inn & Suites Davenport - Quad Cities

8/10 Good

"Excelente, Todo perfecto"

Best Western Muscatine / Pearl City Hotel

8/10 Good

"Nice room. Nice staff. Okay breakfast. One of the beds were not made. After lifting comforter we noticed the top sheet was pulled back. The bed was moist. No pillow cases on 2 pillows & stain on fitted sheet. Staff offered new room, but we were fully unpacked. No discount offered. Luckily we only needed one bed."

Sleep Inn & Suites Davenport - Quad Cities

8/10 Good

"When we first pulled in I was a little hesitate on the hotel due to how unkept it looked on the outside. Tall grass dead flowers and garbage. When we checked in the lady at the front desk seemed very tired. She seemed to have been dealing with an unhappy guest. We got our room key and headed for the room. As soon as we unlocked the door we were hit with an obvious cigarette odor. We booked a non smoking room. We called the front desk to let her know we obviously were given a smoking room and her fix was offering air freshener and to open windows. Other than that no issues"

Hampton Inn Muscatine

8/10 Good

"A small fridge in the room would have been useful. Many hotels/motels still have them."

Room 1

Change your mind

Treat yourself

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Check availability on Muscatine Business Hotels

Our top choices for Muscatine business-friendly hotels

1. Best Western Muscatine / Pearl City Hotel