A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Mytilene Vacation Rentals

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Check prices for these dates

In two weeks
30 Oct - 1 Nov
In two months
11 Dec - 13 Dec
In three months
8 Jan - 10 Jan
In four months
5 Feb - 7 Feb

Our top choices for Mytilene vacation rentals

A pathway flanked by lush greenery and palm trees, leading to a distant structure.

1. Loriet Hotel

Loriet Hotel
4.0 star property
Lesvos
8.4 out of 10, Very good, (96 reviews)
"Lovely mansion house and a great breakfast."
United States
Malcolm
The price is AED 262
AED 299 total
includes taxes & fees
2 Nov - 3 Nov
Loriet Hotel
A hotel room with two beds, a desk, and a view of the ocean.

2. Akti Vigla Premium

Akti Vigla Premium
Lesvos
10.0 out of 10, Exceptional, (23 reviews)
"Breakfast was fantastic and we loved the engineering of the patio doors. They tilt and open"
United States
Rebecca
The price is AED 235
AED 259 total
includes taxes & fees
1 Nov - 2 Nov
Akti Vigla Premium
A woman sitting by a pool with a drink, overlooking a modern outdoor bar and lounge area with outdoor seating.

3. Elies Residences

Elies Residences
Lesvos
9.8 out of 10, Exceptional, (37 reviews)
"Beautiful quiet nice little place.Very cosy !!"
Australia
Anonymous traveler
The price is AED 404
AED 451 total
includes taxes & fees
15 Oct - 16 Oct
Elies Residences
A modern kitchen with a grey sofa and a wooden table in the living area.

4. Sofie's Choice Mytilini

Sofie's Choice Mytilini
Lesvos
9.6 out of 10, Exceptional, (12 reviews)
"Amazing experience with all the necessities. "
Australia
Peter
The price is AED 280
AED 340 total
includes taxes & fees
21 Oct - 22 Oct
Sofie's Choice Mytilini
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mytilene Hotel Reviews

Ampoulos Rooms & Apartments

Ampoulos Rooms & Apartments

10/10 Excellent
"Very friendly family hotel"
Khanh 2-night trip
Posted 2 months ago
Ampoulos Rooms & Apartments

Frequently asked questions

Are there vacation rentals in Mytilene?

Yes, we give you a choice of vacation rentals close to the most popular attractions in Mytilene, or you can select a more remote option if you want a relaxing place to stay. Nature enthusiasts will enjoy the seaside in Mytilene. Make sure you have time to check out the museums and monuments during your trip.

What's the top vacation rental that Mytilene has to offer?

Spacious , modern beachfront maisonette in a verdant suburb near the city centre: This Mytilene vacation home rental is on the beach and equipped with air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other homes for rent in Mytilene include V House Cozy & Quiet Escape and Villa Laurette Kratigos, Private Escape with Views.

How many vacation rentals will I find in Mytilene?

Choose from 15 Expedia vacation rentals in Mytilene for a memorable vacation.

What’s there to see and do in Mytilene?

Enjoy the outdoors at Thermes Gera Hot Springs and Thermi Beach, or simply take in cultural attractions like Ecclesiastical Byzantine Museum and Theriade Library and Museum of Modern Art. While here, Port of Mytilene and Mytilini Castle are other places worth a visit.

What’s a vacation rental in Mytilene like?

A vacation rental is a private property you can stay in for a couple of days or more in Mytilene. Vacation rentals provide amenities such as kitchens and laundry facilities so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of seclusion away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive choice for family trips.