Find Resorts & Hotels with Spas in Northeast Missouri, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Northeast Missouri Resorts & Hotels with Spas
Tonight
16 Sep - 17 SepTomorrow
17 Sep - 18 SepThis weekend
18 Sep - 20 SepNext weekend
25 Sep - 27 SepOur top choices for Northeast Missouri hotels with a spa
1. Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - HannibalHannibal
- Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
AED 284
AED 339 total
includes taxes & fees
20 Sep - 21 Sep
2. Holiday Inn Quincy East by IHG
Holiday Inn Quincy East by IHGQuincy
- Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
AED 452
AED 515 total
includes taxes & fees
27 Sep - 28 Sep
AED 617
AED 749 total
includes taxes & fees
17 Sep - 18 Sep
4. Ameristar Casino Resort and Spa
Ameristar Casino Resort and SpaSt. Charles
- Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AED 548
AED 702 total
includes taxes & fees
12 Oct - 13 Oct
5. 21C Museum Hotel St Louis
21C Museum Hotel St LouisDowntown West
- Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
AED 528
AED 635 total
includes taxes & fees
11 Oct - 12 Oct
6. Hermann Hill
Hermann HillHermann
- Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
AED 1,253
AED 1,441 total
includes taxes & fees
29 Sep - 30 Sep
7. The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. LouisClayton
- Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
AED 2,016
AED 2,354 total
includes taxes & fees
20 Sep - 21 Sep
8. Four Seasons Hotel St Louis
Four Seasons Hotel St LouisDowntown St. Louis
- Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
AED 1,377
AED 1,611 total
includes taxes & fees
17 Sep - 18 Sep
Spa hotels with free breakfast in Northeast Missouri
AED 452
AED 515 total
includes taxes & fees
27 Sep - 28 Sep
AED 284
AED 339 total
includes taxes & fees
20 Sep - 21 Sep
AED 528
AED 635 total
includes taxes & fees
11 Oct - 12 Oct
AED 1,253
AED 1,441 total
includes taxes & fees
29 Sep - 30 Sep
AED 2,016
AED 2,354 total
includes taxes & fees
20 Sep - 21 Sep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesTop Northeast Missouri Hotel Reviews
Clayton Plaza Hotel & Extended Stay
10/10 Excellent
"Let's start with...we have stayed here several times & love it! Started with Patrick at the front desk gave us dinner recommendations & helpful hints to take the train to Busch Stadium. He was very helpful & very personable. He even remembered us when we checked out & asked if we enjoyed the game! If you've ever stayed here, you know how amazing the bathroom/showers (yes plural) are! Now the not so good...we had our 15 year old son with us, who was sleeping on the pull out couch. We looked & looked, but could not find bedding anywhere, so we called the front desk for some. They brought a set of sheets but no blanket or anything. Including no pillow. Upon opening the pull out couch, there was still a dirty sheet on it and a pillow shoved down the back of the couch. Also during our stay, the parking garage was under construction so it couldn't be utilized as well as previous visits. None of these were deal breakers and we will definitely stay here again!"
The Westin St. Louis
10/10 Excellent
"Above exceptional"
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"Clean room"
Pear Tree Inn St. Louis Near Union Station
10/10 Excellent
"It is conveniently located near places and attractions in the downtown area of St Louis. Has free parking. very clean and the staff was very helpful and friendly. The only thing I didn't like were the feather pillows."
Explore a world of travel with Expedia
- 4 Star Hotels in Macon
- Hotels with an Indoor Pool in Moberly
- 2 Star Hotels in Monroe City
- Casino Hotels in Canton
- Condo Rentals in Monroe City
- Hotels with Bars in Kirksville
- Cabin Rentals in Monroe City
- Cheap Hotels in Palmyra
- Marriott Hotels & Resorts in Rutledge
- Cabin Rentals in Hurdland
- Independent Hotels in Edina
- 3 Star Hotels in Lentner
- 5 Star Hotels in Holliday
- Pet-Friendly Hotels in Kirksville
- Best Western Hotels in Shelbina
- Pet-Friendly Hotels in Northeast Missouri
- Vacation Homes in La Plata
- Casino Hotels in Northeast Missouri
- 3 Star Hotels in Edina
- Hotels with Hot Tubs in Hannibal
- Wyndham Hotels in Macon
- Wyndham Hotels in La Plata
- Hotels with smoking rooms in Macon
- Vacation Homes in Macon
- Cabin Rentals in La Plata
- 4 Star Hotels in La Plata
- Lodges in Northeast Missouri
- Cabin Rentals in Excello
- Best Western Hotels in Northeast Missouri
- Vacation Homes in Gibbs
- Best Western Hotels in Holliday
- 3 Star Hotels in Shelbina
- Budget Host Hotels in Maywood
- Red Roof Inn Hotels in Northeast Missouri
- Motels in Gibbs
- Cottages in Excello
- Hotel Wedding Venues Hotels in Macon
- La Quinta Inn & Suites Hotels in Northeast Missouri
- Independent Hotels in La Plata
- Golf Hotels in La Plata
- B&B in Shelbina
- Pet-Friendly Hotels in Canton
- La Plata Hotels
- Wyndham Hotels in Shelbina
- Family Hotels in Northeast Missouri
- Wyndham Hotels in Shelbyville
- Historic Hotels in Hannibal
- Luxury Hotels in Northeast Missouri
- Hotels near Maples Repertory Theatre
- 4 Star Hotels in Hurdland
- Lodges in Excello
- Flights from Bogotá (BOG) to Kirksville (IRK)
- Flights from Marquette (MQT) to Kirksville (IRK)
- Flights from Columbia (COU) to Kirksville (IRK)
- Flights from Hurdland
- Flights from Frankfurt (FRA) to Kirksville (IRK)
- Flights from Dalaman (DLM) to Kirksville (IRK)
- Flights from Valparaiso (VPZ) to Kirksville (IRK)
- Flights from Monroe City
- Flights from Bangor (BGR) to Kirksville (IRK)
- Flights from Alta Floresta (AFL) to Kirksville (IRK)
- Flights from Lagos (LOS) to Kirksville (IRK)
- Flights from Kaltag (KAL) to Kirksville (IRK)
- Flights from La Plata
- Flights from Shelbina
- Flights from Prince Albert (YPA) to Kirksville (IRK)
- Flights from Yangon (RGN) to Kirksville (IRK)
- Flights from Holland (HLM) to Kirksville (IRK)
- Flights from Ketchikan (KTN) to Kirksville (IRK)
- Flights from Tunica (UTM) to Kirksville (IRK)
- Flights from Liverpool (LPL) to Kirksville (IRK)
- Flights from Kubin Island (KUG) to Kirksville (IRK)
- Flights from Cocos Islands (CCK) to Kirksville (IRK)
- Flights from Greenville (PGV) to Kirksville (IRK)
- Flights from Albuquerque (ABQ) to Kirksville (IRK)
- Flights from Northeast Missouri
- Flights from Phoenix (PHX) to Kirksville (IRK)
- Flights from Denver (DEN) to Kirksville (IRK)
- Flights from Jabalpur (JLR) to Kirksville (IRK)
- Flights from Kirksville Municipal
- Flights from Santa Maria (RIA) to Kirksville (IRK)
- Flights from Huntsville (HSV) to Kirksville (IRK)
- Flights from Camiri (CAM) to Kirksville (IRK)
- Flights from Glasgow (GLA) to Kirksville (IRK)
- Flights from Macon
- Flights from Jeddah (JED) to Kirksville (IRK)
- Flights from Pristina (PRN) to Kirksville (IRK)
- Flights to Macon
- Flights from Santa Isabel do Rio Negro (IRZ) to Kirksville (IRK)
- Flights from Mojave (MHV) to Kirksville (IRK)
- Flights from Tamchy (IKU) to Kirksville (IRK)
- Flights from Holliday
- Flights from Halifax (YHZ) to Kirksville (IRK)
- Flights from Madison (MSN) to Kirksville (IRK)
- Flights from El Paso (ELP) to Kirksville (IRK)
- Flights from Anchorage (ANC) to Kirksville (IRK)
- Flights from Oslo (OSL) to Kirksville (IRK)
- Flights from Vojens (SKS) to Kirksville (IRK)
- Flights from Chicago (PWK) to Kirksville (IRK)
- Flights from Orlando (SFB) to Kirksville (IRK)