Find Resorts & Hotels with Spas in Northeast Missouri, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Northeast Missouri Resorts & Hotels with Spas
Tonight
31 Aug - 1 SepTomorrow
1 Sep - 2 SepThis weekend
4 Sep - 6 SepNext weekend
11 Sep - 13 SepOur top choices for Northeast Missouri hotels with a spa
1. Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - HannibalHannibal
- Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
AED 275
AED 329 total
includes taxes & fees
20 Sep - 21 Sep
AED 617
AED 749 total
includes taxes & fees
1 Sep - 2 Sep
3. Holiday Inn Quincy East by IHG
Holiday Inn Quincy East by IHGQuincy
- Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
AED 452
AED 515 total
includes taxes & fees
27 Sep - 28 Sep
4. Ameristar Casino Resort and Spa
Ameristar Casino Resort and SpaSt. Charles
- Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AED 610
AED 774 total
includes taxes & fees
7 Sep - 8 Sep
5. 21C Museum Hotel St Louis
21C Museum Hotel St LouisDowntown West
- Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
AED 528
AED 635 total
includes taxes & fees
20 Sep - 21 Sep
6. Hermann Hill
Hermann HillHermann
- Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
AED 1,292
AED 1,485 total
includes taxes & fees
1 Sep - 2 Sep
7. The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. LouisClayton
- Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
AED 2,016
AED 2,354 total
includes taxes & fees
20 Sep - 21 Sep
8. Four Seasons Hotel St Louis
Four Seasons Hotel St LouisDowntown St. Louis
- Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
AED 1,377
AED 1,611 total
includes taxes & fees
1 Sep - 2 Sep
Spa hotels with free breakfast in Northeast Missouri
AED 275
AED 329 total
includes taxes & fees
20 Sep - 21 Sep
AED 452
AED 515 total
includes taxes & fees
27 Sep - 28 Sep
AED 528
AED 635 total
includes taxes & fees
20 Sep - 21 Sep
AED 1,292
AED 1,485 total
includes taxes & fees
1 Sep - 2 Sep
AED 2,016
AED 2,354 total
includes taxes & fees
20 Sep - 21 Sep
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesTop Northeast Missouri Hotel Reviews
Pear Tree Inn St. Louis Near Union Station
8/10 Good
"Clean hotel, friendly staff,"
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"We stay every time we come down in a convenient area"
Ameristar Casino Resort and Spa
8/10 Good
"All went well room clean, staff outstanding"
Hilton St. Louis at the Ballpark
8/10 Good
"Our room was over $300 a night and it had paint chipping everywhere and needed repairs. It was clean just out of date."
Explore a world of travel with Expedia
- 4 Star Hotels in Macon
- Hotels with an Indoor Pool in Moberly
- 2 Star Hotels in Monroe City
- Casino Hotels in Canton
- Condo Rentals in Monroe City
- Hotels with Bars in Kirksville
- Cabin Rentals in Monroe City
- Cheap Hotels in Palmyra
- Marriott Hotels & Resorts in Rutledge
- Cabin Rentals in Hurdland
- Independent Hotels in Edina
- 3 Star Hotels in Lentner
- 5 Star Hotels in Holliday
- Pet-Friendly Hotels in Kirksville
- Best Western Hotels in Shelbina
- Pet-Friendly Hotels in Northeast Missouri
- Vacation Homes in La Plata
- Casino Hotels in Northeast Missouri
- 3 Star Hotels in Edina
- Hotels with Hot Tubs in Hannibal
- Wyndham Hotels in Macon
- Wyndham Hotels in La Plata
- Hotels with smoking rooms in Macon
- Vacation Homes in Macon
- Cabin Rentals in La Plata
- 4 Star Hotels in La Plata
- Lodges in Northeast Missouri
- Cabin Rentals in Excello
- Best Western Hotels in Northeast Missouri
- Vacation Homes in Gibbs
- Best Western Hotels in Holliday
- 3 Star Hotels in Shelbina
- Budget Host Hotels in Maywood
- Red Roof Inn Hotels in Northeast Missouri
- Motels in Gibbs
- Cottages in Excello
- Hotel Wedding Venues Hotels in Macon
- La Quinta Inn & Suites Hotels in Northeast Missouri
- Independent Hotels in La Plata
- Golf Hotels in La Plata
- B&B in Shelbina
- Pet-Friendly Hotels in Canton
- La Plata Hotels
- Wyndham Hotels in Shelbina
- Family Hotels in Northeast Missouri
- Wyndham Hotels in Shelbyville
- Historic Hotels in Hannibal
- Luxury Hotels in Northeast Missouri
- Hotels near Maples Repertory Theatre
- 4 Star Hotels in Hurdland
- Lodges in Excello
- Flights from Bogotá (BOG) to Kirksville (IRK)
- Flights from Marquette (MQT) to Kirksville (IRK)
- Flights from Columbia (COU) to Kirksville (IRK)
- Flights from Hurdland
- Flights from Frankfurt (FRA) to Kirksville (IRK)
- Flights from Dalaman (DLM) to Kirksville (IRK)
- Flights from Valparaiso (VPZ) to Kirksville (IRK)
- Flights from Monroe City
- Flights from Bangor (BGR) to Kirksville (IRK)
- Flights from Alta Floresta (AFL) to Kirksville (IRK)
- Flights from Lagos (LOS) to Kirksville (IRK)
- Flights from Kaltag (KAL) to Kirksville (IRK)
- Flights from La Plata
- Flights from Shelbina
- Flights from Prince Albert (YPA) to Kirksville (IRK)
- Flights from Yangon (RGN) to Kirksville (IRK)
- Flights from Holland (HLM) to Kirksville (IRK)
- Flights from Ketchikan (KTN) to Kirksville (IRK)
- Flights from Tunica (UTM) to Kirksville (IRK)
- Flights from Liverpool (LPL) to Kirksville (IRK)
- Flights from Kubin Island (KUG) to Kirksville (IRK)
- Flights from Cocos Islands (CCK) to Kirksville (IRK)
- Flights from Greenville (PGV) to Kirksville (IRK)
- Flights from Albuquerque (ABQ) to Kirksville (IRK)
- Flights from Northeast Missouri
- Flights from Phoenix (PHX) to Kirksville (IRK)
- Flights from Denver (DEN) to Kirksville (IRK)
- Flights from Jabalpur (JLR) to Kirksville (IRK)
- Flights from Kirksville Municipal
- Flights from Santa Maria (RIA) to Kirksville (IRK)
- Flights from Huntsville (HSV) to Kirksville (IRK)
- Flights from Camiri (CAM) to Kirksville (IRK)
- Flights from Glasgow (GLA) to Kirksville (IRK)
- Flights from Macon
- Flights from Jeddah (JED) to Kirksville (IRK)
- Flights from Pristina (PRN) to Kirksville (IRK)
- Flights to Macon
- Flights from Santa Isabel do Rio Negro (IRZ) to Kirksville (IRK)
- Flights from Mojave (MHV) to Kirksville (IRK)
- Flights from Tamchy (IKU) to Kirksville (IRK)
- Flights from Holliday
- Flights from Halifax (YHZ) to Kirksville (IRK)
- Flights from Madison (MSN) to Kirksville (IRK)
- Flights from El Paso (ELP) to Kirksville (IRK)
- Flights from Anchorage (ANC) to Kirksville (IRK)
- Flights from Oslo (OSL) to Kirksville (IRK)
- Flights from Vojens (SKS) to Kirksville (IRK)
- Flights from Chicago (PWK) to Kirksville (IRK)
- Flights from Orlando (SFB) to Kirksville (IRK)