A large eye sculpture in a park surrounded by trees.

Find Resorts & Hotels with Spas in Northeast Missouri, MO

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Check availability on Northeast Missouri Resorts & Hotels with Spas

Tonight
7 Oct - 8 Oct
Tomorrow
8 Oct - 9 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel room with a bed, a sofa, a desk, and a lamp.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
AED 279
AED 332 total
includes taxes & fees
11 Oct - 12 Oct
Comfort Inn & Suites - Hannibal
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
AED 617
AED 749 total
includes taxes & fees
8 Oct - 9 Oct
Truitt Hotel
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
An outdoor patio with tables and chairs, green umbrellas, and string lights.

3. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
AED 474
AED 540 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Quincy East by IHG
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
AED 528
AED 635 total
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
A spa area with a massage table, a hot tub, and a grill.
A row of houses with a driveway leading to a gated entrance.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A hot tub, a fire pit, and a view of a lake.

5. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
AED 1,211
AED 1,393 total
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bakery display case with various pastries and cakes.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AED 621
AED 787 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
AED 2,127
AED 2,483 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
AED 1,377
AED 1,611 total
includes taxes & fees
8 Oct - 9 Oct
Four Seasons Hotel St Louis
View all properties

Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A hotel room with a bed, a sofa, a desk, and a lamp.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
AED 279
AED 332 total
includes taxes & fees
11 Oct - 12 Oct
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
An outdoor patio with tables and chairs, green umbrellas, and string lights.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
AED 474
AED 540 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Quincy East by IHG
A hot tub, a fire pit, and a view of a lake.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A bathroom with a bathtub, a shower, and a vanity with a mirror.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.

Hermann Hill

Hermann Hill
Hermann
AED 1,211
AED 1,393 total
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
AED 528
AED 635 total
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
AED 2,127
AED 2,483 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"I love the Moonrise and will stay here anytime I come to St. Louis. I have stayed here multiple times and never had a negative experience. Easy parking, walking to food, next door to concert venues, plus pet friendly. The rooftop bar is great too!"
Rachel 1-night trip
Posted 16 hours ago
Moonrise Hotel
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"One of the only hotels in the area with free on-site parking, can park in the garage on site or in regular lot and come and go and you please"
Dustin 4-night trip
Posted 18 hours ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Walking distance from the soccer stadium"
Larry 1-night trip
Posted 19 hours ago
Drury Plaza Hotel St. Louis Union Station

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