A large eye sculpture in a park surrounded by trees.

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Check prices for these dates

In two weeks
6 Nov - 8 Nov
In two months
18 Dec - 20 Dec
In three months
15 Jan - 17 Jan
In four months
12 Feb - 14 Feb

Our top choices for Northeast Missouri vacation homes

A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

1. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (47 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
The price is AED 364
AED 712 total
includes taxes & fees
31 Oct - 1 Nov
Aunt Lele's Cozy Cottage
A living room with a brown sofa, a wooden coffee table, a television on a stand, and a bookshelf.

2. Unwind on Vine

Unwind on Vine
Macon
9.6 out of 10, Exceptional, (38 reviews)
"Awesome place! Clean, spacious, and quiet. Highly recommend for short or long stays."
United States
Josh C.
The price is AED 606
AED 961 total
includes taxes & fees
14 Nov - 15 Nov
Unwind on Vine
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

3. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (54 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
The price is AED 324
AED 729 total
includes taxes & fees
27 Oct - 28 Oct
Spacious & Modern 2BR Home with Attached Garage
A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

4. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (17 reviews)
"Had a great time in Hannibal."
United States
Terry
The price is AED 481
AED 1,254 total
includes taxes & fees
2 Nov - 3 Nov
Vibey home a few blocks from downtown Hannibal
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

5. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (70 reviews)
"Very nice experience, and close to all the historical sites!"
United States
Steve G.
The price is AED 408
AED 684 total
includes taxes & fees
9 Nov - 10 Nov
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

6. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (227 reviews)
"The cottage was in a quiet location, clean, and with easy access to both Quincy, IL and Hannibal, MO. The property owner was available and easy to contact."
United States
Jodi
The price is AED 477
AED 903 total
includes taxes & fees
3 Nov - 4 Nov
Peaceful, Country Cottage with Open Floor Plan
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

7. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (22 reviews)
"House was perfect for our stay."
United States
Brent W.
The price is AED 451
AED 1,215 total
includes taxes & fees
22 Nov - 23 Nov
Modern and comfy home five minutes from downtown
A covered patio with string lights, a seating area, and a small table.

8. TJ’s Country Getaway- Dog Friendly

TJ’s Country Getaway- Dog Friendly
Union
10.0 out of 10, Exceptional, (52 reviews)
"The property was great, cozy touches, clean and simply lovely. It was great to be able to travel with my dog!"
United States
Sherry
TJ’s Country Getaway- Dog Friendly
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

9. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.6 out of 10, Exceptional, (28 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
The price is AED 545
AED 853 total
includes taxes & fees
26 Oct - 27 Oct
The John Sydney House - Family and Pet Friendly Historic Home Downtown
Property grounds

10. Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
Imperial
9.8 out of 10, Exceptional, (8 reviews)
"Thank you we enjoyed the place but we would like to get some more nights if all possible"
United States
Tommy H.
The price is AED 278
AED 431 total
includes taxes & fees
26 Oct - 27 Oct
Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island with bar stools.

11. Shouse Near Mark Twain Lake!

Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (13 reviews)
"This was our second stay, and it was just as great as the first time! Plenty of room to play, huge TVs for family movie night, and a well equipped kitchen for serving meals. Thank you! "
United States
Christina H.
The price is AED 845
AED 1,202 total
includes taxes & fees
24 Nov - 25 Nov
Shouse Near Mark Twain Lake!
A modern living room with a sofa, a wooden dining table with stools, a kitchen area with cabinets and a TV, and a hallway leading to a door.

12. Family friendly 3 bedroom home in Kahoka MO

Family friendly 3 bedroom home in Kahoka MO
Kahoka
9.4 out of 10, Exceptional, (13 reviews)
"Absolutely friendly and welcoming hosts. "
United States
Jay M.
The price is AED 523
AED 804 total
includes taxes & fees
26 Oct - 27 Oct
Family friendly 3 bedroom home in Kahoka MO
A porch with two turquoise Adirondack chairs and a small table, surrounded by well-maintained greenery and a white house with black shutters.

13. WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (42 reviews)
"This is a fantastic place to stay. We will return in the future."
United States
Mike S.
The price is AED 599
AED 1,080 total
includes taxes & fees
8 Nov - 9 Nov
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
A living room with a sofa set, a coffee table, and a TV.

14. Hickory Lake House

Hickory Lake House
3.0 star property
Wright City
The price is AED 1,028
AED 1,614 total
includes taxes & fees
25 Oct - 26 Oct
Hickory Lake House
A dining area with a wooden table, grey upholstered chairs, a bench, a patterned rug, a brick wall, a framed picture, and a potted plant.

15. Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (180 reviews)
"Great place!"
United States
Arthur S.
The price is AED 272
AED 589 total
includes taxes & fees
29 Oct - 30 Oct
Centrally located in the Tower Grove East neighborhood!
A living room with a wooden entertainment center, a white sofa, and a dining area with a white railing.

16. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (46 reviews)
"Excellent communication and service, very clean, and nice place to stay. We enjoyed our stay!"
United States
Jennifer M.
The price is AED 716
AED 1,153 total
includes taxes & fees
26 Oct - 27 Oct
Spacious, cozy home in Saint Louis
A living room with a sofa, coffee table, and patterned rug. There is a dining area with a bar and stools.

17. Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters

Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters
St. Peters
10.0 out of 10, Exceptional, (20 reviews)
"What a great place to stay! Clean, well stocked, and very spacious. Would definitely book again."
United States
Lynn D.
The price is AED 350
AED 1,073 total
includes taxes & fees
26 Oct - 27 Oct
Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters
A two-story house with a covered porch, stone exterior, and a large tree in the foreground.

18. Pet and kid friendly duplex with 2 bedrooms

Pet and kid friendly duplex with 2 bedrooms
Pacific
9.6 out of 10, Exceptional, (49 reviews)
"Unit was very clean and comfortable. Lots of space inside and outside for yard and parking. Host was responsive to our questions. Local restaurants with good food and service were nearby."
United States
John D.
The price is AED 528
AED 678 total
includes taxes & fees
25 Oct - 26 Oct
Pet and kid friendly duplex with 2 bedrooms
A brick house with a front porch, a Christmas wreath, and a Christmas tree.

19. Schoolhouse: Dog-friendly, Large Yard, near Purina, Wheelchair friendly

Schoolhouse: Dog-friendly, Large Yard, near Purina, Wheelchair friendly
Washington
10.0 out of 10, Exceptional, (13 reviews)
"Another wonderful stay at Pikes Peak Schoolhouse. We love the heritage, and the close proximity to things."
United States
Todd R.
The price is AED 965
AED 1,169 total
includes taxes & fees
26 Oct - 27 Oct
Schoolhouse: Dog-friendly, Large Yard, near Purina, Wheelchair friendly
A two-story house with a covered porch, a stone facade, and a well-maintained lawn.

20. Kid and pet friendly 2 nd floor duplex

Kid and pet friendly 2 nd floor duplex
Pacific
9.0 out of 10, Wonderful, (31 reviews)
"Very clean, nicely decorated."
United States
Amanda Q.
The price is AED 650
AED 829 total
includes taxes & fees
7 Nov - 8 Nov
Kid and pet friendly 2 nd floor duplex
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Northeast Missouri Hotel Reviews

21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"Had a great time from Valet to the front desk and housekeepers everyone was nice and attentive the room was excellent. The museum with the art was amazing a lot of places to take pictures and take everything in. Great downtown location as well. 10/10 would recommend"
Zerell 3-night trip
Posted 1 hour ago
21C Museum Hotel St Louis

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