O Brien, FL Vacation Homes from AED 506

O Brien Vacation Homes
Florida
United States of America
Expedia.ae

A calm river with clear water, surrounded by dense trees and rocky banks.

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Our top choices for O Brien vacation homes

A bedroom with a bed, bedside lamps, a headboard, a window with curtains, and a wall sign.

1. Cozy Lake House, Hot Tub & Close to FL Springs

Cozy Lake House, Hot Tub & Close to FL Springs

Branford

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "

Ashley L.

Cozy Lake House, Hot Tub & Close to FL Springs

A modern kitchen with wooden cabinets, a central island with stools, a stove, and a dining area with chairs.

Our open-concept kitchen and island seating make it easy to stay part of the conversation while you cook. Bathed in natural light and styled with contemporary finishes, it’s as beautiful as it is functional.

Sleek design meets ultimate comfort. With clean lines, soothing green accents, and plenty of natural light, this bedroom offers a sophisticated space to unwind after a day of adventures.

A modern living room with a grey sofa, a coffee table, and a TV. There is a kitchen area with wooden cabinets and a dining space with patterned chairs.

2. The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill

Fort White

9.4 out of 10, Exceptional, (17 reviews)

9.4/10

Exceptional

(17 reviews)

"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "

Nicole

The price is AED 386

AED 386

AED 1,033 total

includes taxes & fees

18 Oct - 19 Oct

The Riverhead | Springs • Pavilion • Grill

A wooden deck with two benches and a table, surrounded by a wooden fence and trees.

A compact kitchen with wooden cabinets, a microwave, a coffee maker, a sink, and a refrigerator.

A wooden bench and table on a wooden deck with a green railing, a beige wall, and a door in the background.

3. SpringHouse at Convict Springs

SpringHouse at Convict Springs

Mayo

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

The price is AED 404

AED 404

AED 506 total

includes taxes & fees

18 Oct - 19 Oct

SpringHouse at Convict Springs

A house with a porch and a garden with yellow flowers.

A dining area with a wooden table and four chairs, a stone fireplace, and motivational wall art.

A wooden deck with steps leading to a house, surrounded by greenery and a small garden area.

A bedroom with a bed, a TV, an air conditioner, and a window with curtains.

4. Nature Cabin Itchetucknee Springs Private Access ~ Nature Lovers Only

Nature Cabin Itchetucknee Springs Private Access ~ Nature Lovers Only

Fort White

The price is AED 367

AED 367

AED 982 total

includes taxes & fees

18 Oct - 19 Oct

Nature Cabin Itchetucknee Springs Private Access ~ Nature Lovers Only

A living room with a television on a wooden stand, a wicker chair, a dark sofa, and a door to another room.

A compact kitchen with wooden cabinets, a white refrigerator, a stove, and a sink.

A picnic table and a mailbox in a wooded area with a small building in the background.

A bedroom with a bed, a ceiling fan, a nightstand, a lamp, and a wall decoration.

5. O'LE LADYBUG COTTAGE

O'LE LADYBUG COTTAGE

Lake City

9.6 out of 10, Exceptional, (57 reviews)

9.6/10

Exceptional

(57 reviews)

"Everything was great will stay again if I’m ever in the area"

regina

The price is AED 357

AED 357

AED 771 total

includes taxes & fees

19 Oct - 20 Oct

O'LE LADYBUG COTTAGE

A kitchen area with a wicker basket containing folded towels, a bottle of dish soap, and a sponge.

A living room with a grey sofa, wooden chairs, a dining table with chairs, a chandelier, and large windows with blinds.

A dining area with a chandelier, white chairs, and a table with floral placemats.

A modern kitchen with white cabinets, a stainless steel dishwasher, a sink with a faucet, and a countertop with a basket and jars.

6. Nature + Music + Town - Cozy Farmhouse Retreat

Nature + Music + Town - Cozy Farmhouse Retreat

Live Oak

10.0 out of 10, Exceptional, (22 reviews)

10/10

Exceptional

(22 reviews)

"It feels just like staying with family "

Starr T.

The price is AED 520

AED 520

AED 1,097 total

includes taxes & fees

26 Oct - 27 Oct

Nature + Music + Town - Cozy Farmhouse Retreat

A kitchen with a black induction cooktop, hanging utensils, and a small shelf with kitchen items.

A living room with a sectional sofa, ottoman, and a kitchen in the background.

A green door with a white window, a 'HOME' sign, and a red brick wall.

A compact kitchen with white cabinets, a microwave, and a sink. There is a vase with flowers on the table.

7. Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.

Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.

Lake City

9.2 out of 10, Wonderful, (7 reviews)

9.2/10

Wonderful

(7 reviews)

"Amenities were surprisingly good, glad to have coffee available "

Cindy M.

The price is AED 386

AED 386

AED 673 total

includes taxes & fees

18 Oct - 19 Oct

Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.

A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

A kitchen with wooden cabinets, a central island, a stove, and a microwave.

A bedroom with a bed, a ceiling fan, a window with curtains, a painting, a bathroom door, a small table with a lamp, and a blue chair.

A dining area with a round wooden table, four chairs, and a window with curtains.

8. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai

Old Town

The price is AED 404

AED 404

AED 1,372 total

includes taxes & fees

18 Oct - 19 Oct

< 1 Mi From Suwannee River, Hideaway w/ Lanai

Screened-In Lanai | Dining Table | Bar Area | Private Pool (Not Heated)

A two-story building with a covered porch and a staircase leading to the upper level.

A wooden bar area with a ceiling fan, concrete pillars, and a view of the outdoors.

9. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock

Branford

9.8 out of 10, Exceptional, (9 reviews)

9.8/10

Exceptional

(9 reviews)

"A nice little getaway for a couple of days - great change of pace.While we didn’t bring children, I could see this an ideal place to bring kids and/or a large family to have plenty of space. Our dog (passed after we booked it) would have loved the ability to roam around in a gated area.Owner was very attentive. A tree fell on the wood bridge to the river right before we arrived and she had it fixed within the hour."

Matt W.

The price is AED 966

AED 966

AED 2,242 total

includes taxes & fees

18 Oct - 19 Oct

Suwannee River Retreat: Pet Friendly, Private Dock

A two-story house with a porch, surrounded by trees and a body of water.

A two-story house with a porch and outdoor seating area.

A wooden bed with a quilt, two bedside tables, and lamps.

A kitchen with white cabinets, a wooden island, a stove, and a dining area with a chair and a sofa.

10. Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Live Oak

10.0 out of 10, Exceptional, (85 reviews)

10/10

Exceptional

(85 reviews)

"Perfect home base for my daughter’s wedding weekend! Owner was responding e and accommodating for my questions and needs!"

Lisa P.

The price is AED 493

AED 493

AED 933 total

includes taxes & fees

19 Oct - 20 Oct

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

A spacious living area with a high ceiling, wooden flooring, a dining table with chairs, a sofa, a bookshelf, and a staircase.

A two-story building with a covered porch and a staircase leading to an upper level.

A sunlit room with a tiled floor, a table with chairs, and a window with a view of trees.

A compact kitchen with wooden cabinets, a microwave, a stove, and a dining area with a table and chairs.

11. Beautiful memories are made on the Suwannee River in Mayo Fl

Beautiful memories are made on the Suwannee River in Mayo Fl

Mayo

The price is AED 496

AED 496

AED 1,023 total

includes taxes & fees

27 Oct - 28 Oct

Beautiful memories are made on the Suwannee River in Mayo Fl

A wooden house with a porch and stairs, surrounded by trees.

A spacious living room with a dark wood floor, a leather sofa, a wicker coffee table, and a brown armchair.

A modern kitchen with wooden cabinets, a refrigerator, a coffee maker, and a dining area with wooden chairs and a glass table.

A modern kitchen with wooden cabinets, stainless steel appliances, and a granite countertop.

12. Hillside Abode in the Heart of Historic White Springs and the Suwannee River

Hillside Abode in the Heart of Historic White Springs and the Suwannee River

White Springs

10.0 out of 10, Exceptional, (36 reviews)

10/10

Exceptional

(36 reviews)

"Well worth the cost place was clean organized and a nice little safe haven during our trip "

Cory P.

The price is AED 496

AED 496

AED 1,000 total

includes taxes & fees

18 Oct - 19 Oct

Hillside Abode in the Heart of Historic White Springs and the Suwannee River

A wooden staircase leading to a riverbank with a view of the water and surrounding trees.

A wooden deck leading to a lake with a bench and a lifebuoy.

A spacious hallway with wooden flooring, a bench with floral cushions, a door with a window, and a cabinet with glass doors.

A spacious living room with a wooden staircase, a bookshelf, and a coffee table.

13. The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River

Mayo

9.8 out of 10, Exceptional, (58 reviews)

9.8/10

Exceptional

(58 reviews)

"Was there for a family reunion and was great for what we needed."

Anonymous traveler

The price is AED 496

AED 496

AED 1,034 total

includes taxes & fees

29 Oct - 30 Oct

The Best memories are made on the Suwannee River

A small cabin with a porch, two windows, and a door.

A kitchen with white cabinets, a stainless steel refrigerator, a dining table with chairs, and a clock on the wall.

A modern kitchen with white cabinetry, stainless steel appliances, a granite countertop, and a wooden floor.

A bedroom with a bed, a dresser, a mirror, and a painting on the wall.

14. 3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

Fort White

10.0 out of 10, Exceptional, (5 reviews)

10/10

Exceptional

(5 reviews)

"We loved our stay !"

Melissa R.

The price is AED 551

AED 551

AED 1,259 total

includes taxes & fees

2 Nov - 3 Nov

3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

An outdoor patio with wicker furniture, a grill, and a ceiling fan.

A black Toyota Land Cruiser LS7 parked on a gravel driveway with a white fence and trees in the background.

A compact kitchen with a white countertop, a coffee maker, a toaster, and shelves with kitchenware.

A modern bedroom with a bed, a TV, a small table, and a chair.

15. Cozy 1-bedroom house in delightful High Springs

Cozy 1-bedroom house in delightful High Springs

High Springs

10.0 out of 10, Exceptional, (12 reviews)

10/10

Exceptional

(12 reviews)

"Close to everything, super clean, great hosts."

Sabrina D.

The price is AED 331

AED 331

AED 611 total

includes taxes & fees

18 Oct - 19 Oct

Cozy 1-bedroom house in delightful High Springs

A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

A spacious living room with a floral sofa, a round coffee table, and a ceiling fan.

A rustic cabin with a wooden deck and a staircase leading to a porch.

16. A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous

Mayo

6.0 out of 10, (1 review)

6.0/10

(1 review)

"Overnight night enroute"

Doug M.

The price is AED 863

AED 863

AED 1,034 total

includes taxes & fees

17 Oct - 18 Oct

A-frame on the Suwannee River Rendezvous

A bedroom with a bed, a television mounted on the wall, and a door leading to another room.

A bedroom with two beds, a television, and large windows with blinds.

A single-story house with a metal roof, a front porch, and a small attached garage.

A modern kitchen with grey cabinets, a black refrigerator, stainless steel appliances, and a window with blinds.

17. Downtown three bedroom house with game room and outside lounge area.

Downtown three bedroom house with game room and outside lounge area.

Lake City

9.6 out of 10, Exceptional, (5 reviews)

9.6/10

Exceptional

(5 reviews)

"Great place"

Angie L.

The price is AED 502

AED 502

AED 1,336 total

includes taxes & fees

2 Nov - 3 Nov

Downtown three bedroom house with game room and outside lounge area.

A living room with two black leather sofas, a glass coffee table, a patterned rug, and a painting on the wall.

A modern kitchen with stainless steel appliances, white cabinetry, and a window providing natural light.

A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a stove.

A wooden staircase with white paneling on the walls and a handrail on the left.

18. Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!

Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!

Live Oak

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"We were in town for a baseball state tournament. This was a fantastic place to stay for multiple families. This house has been newly updated and is beautiful in the inside. It was a very short distance to the Sportsplex. The host is very responsive and helpful. I highly recommend this house to all those families coming into Live Oak!"

Tara W.

The price is AED 1,050

AED 1,050

AED 2,448 total

includes taxes & fees

17 Oct - 18 Oct

Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!

A single-story house with a front porch, a small yard, and a tree in front.

A bedroom with two wooden beds, a ceiling fan, a window with blinds, a nightstand with a lamp, and a map on the wall.

A kitchen with a brick wall, wooden shelves, a microwave, a kettle, and a fire extinguisher.

A kitchen with a brick wall, wooden shelves, a microwave, a wooden cabinet, and a countertop with a basket.

19. Cute, Cozy & Near Downtown! Updated Home w/ Porch

Cute, Cozy & Near Downtown! Updated Home w/ Porch

Live Oak

The price is AED 893

AED 893

AED 1,949 total

includes taxes & fees

29 Oct - 30 Oct

Cute, Cozy & Near Downtown! Updated Home w/ Porch

A laundry area with a washing machine, dryer, and shelves with baskets.

A bedroom with a bed, a desk with a computer, and three framed pictures on the wall.

A wooden deck with a stone fireplace, outdoor seating, and a covered grill area.

A compact kitchen with a microwave, coffee maker, and a refrigerator.

20. Nature Cabin Itchetucknee Springs Private Access

Nature Cabin Itchetucknee Springs Private Access

Columbia County

10.0 out of 10, Exceptional, (1 review)

10/10

Exceptional

(1 review)

"Charming place to stay and enjoy the local rivers!"

Shawn

The price is AED 498

AED 498

AED 982 total

includes taxes & fees

1 Nov - 2 Nov

Nature Cabin Itchetucknee Springs Private Access

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top O Brien Hotel Reviews

Hampton Inn & Suites Lake City

10/10 Excellent

"We stopped here last year on our trek to southern Florida too. Such a comfortable beds, friendly staff, and great hotel. Recommend to all our friends da. Breakfast is also very good and included with your stay."

Barbara 1-night trip

Posted 1 day ago

Hampton Inn & Suites Lake City

BlueGem Motel

10/10 Excellent

"Very clean rooms and homey atmosphere!"

Myra 1-night trip

Posted 1 day ago

BlueGem Motel

Baymont by Wyndham Lake City I-75

8/10 Good

"Hotel is in need of major remodeling"

Tom 1-night trip

Posted 3 days ago

Baymont by Wyndham Lake City I-75

Tru by Hilton Lake City

8/10 Good

"Room was clean- shampoo and conditioner were included. Beds were comfortable. Breakfast was also good. Better than most breakfast buffets I have been too. Friendly and helpful staff."

ELIZABETH 1-night trip

Posted 4 days ago

Tru by Hilton Lake City

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10/10 Excellent

"Great for my sons and grandsons to play for a long weekend. Lots of room and games inside and huge yard to play in. Ideal if you have a boat to enjoy the river."

Richard H. 2-night trip

Posted 1 month ago

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Search Vacation Homes in O Brien

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for O Brien vacation homes

1. Cozy Lake House, Hot Tub & Close to FL Springs

2. The Riverhead | Springs • Pavilion • Grill

3. SpringHouse at Convict Springs

4. Nature Cabin Itchetucknee Springs Private Access ~ Nature Lovers Only

5. O'LE LADYBUG COTTAGE

6. Nature + Music + Town - Cozy Farmhouse Retreat

7. Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.

8. < 1 Mi From Suwannee River, Hideaway w/ Lanai

9. Suwannee River Retreat: Pet Friendly, Private Dock

10. Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

11. Beautiful memories are made on the Suwannee River in Mayo Fl

12. Hillside Abode in the Heart of Historic White Springs and the Suwannee River

13. The Best memories are made on the Suwannee River

14. 3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

15. Cozy 1-bedroom house in delightful High Springs

16. A-frame on the Suwannee River Rendezvous

17. Downtown three bedroom house with game room and outside lounge area.

18. Modern 5BR Live Oak Haven – Minutes from Suwannee Music Park & Springs!

19. Cute, Cozy & Near Downtown! Updated Home w/ Porch

20. Nature Cabin Itchetucknee Springs Private Access

Find vacation rentals that suit your style

Top O Brien Hotel Reviews

Hampton Inn & Suites Lake City