A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

Find Resorts & Hotels with Spas in O'Fallon, MO

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Check availability on O'Fallon Resorts & Hotels with Spas

Tonight
24 Aug - 25 Aug
Tomorrow
25 Aug - 26 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Our top choices for O'Fallon hotels with a spa

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AED 542
AED 694 total
includes taxes & fees
7 Sep - 8 Sep
Ameristar Casino Resort and Spa
View all properties

Choose what matters most at spa hotels in O'Fallon

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top O'Fallon Hotel Reviews

The Wildwood Hotel

The Wildwood Hotel

10/10 Excellent
"The front desk staff, housekeepers and Breakfast area were stellar."
Martha 1-night trip
Posted 8 hours ago
The Wildwood Hotel
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

10/10 Excellent
"Enjoyed our short stay"
Reeshemah 3-night trip
Posted 9 hours ago
Drury Inn & Suites St. Louis Airport
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Great location and atmosphere! Rooms are so spacious and nice. Will definitely stay again!"
Brittni 1-night trip
Posted 12 hours ago
Ameristar Casino Resort and Spa
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

8/10 Good
"It’s was like a castle but finding rooms was a doozy"
ShaMarla 1-night trip
Posted 3 days ago
Hilton St. Louis Frontenac

Frequently asked questions

Looking for a spa hotel in O'Fallon?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the lakeside setting in O'Fallon - worth a picture or two! Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Take in some sights and attractions while you're in O'Fallon by visiting CarShield Field, 9-11 Memorial, and Mississippi River. If you have a bit of extra time while you're in the area, you might want to check out Alligator Creek Aquatic Center and Golf Headquarters.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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