A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

Find Resorts & Hotels with Spas in O'Fallon, MO

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Check availability on O'Fallon Resorts & Hotels with Spas

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for O'Fallon hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bakery display case with various pastries and cakes.
A bar area with multiple seating arrangements, a stage, and a chandelier.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
AED 631
AED 798 total
includes taxes & fees
3 Nov - 4 Nov
Ameristar Casino Resort and Spa
View all properties

Choose what matters most at spa hotels in O'Fallon

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top O'Fallon Hotel Reviews

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

10/10 Excellent
"Rooms were nice, spacious and clean. We got in late so didn't use many of the amenities. Breakfast was nice. Rooms were very clean, well lit and roomy. Great value for the money."
Scott 1-night trip
Posted 4 days ago
Holiday Inn Express St. Louis West - O'Fallon by IHG

Frequently asked questions

Looking for a spa hotel in O'Fallon?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the lakeside setting in O'Fallon - worth a picture or two! Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Take in some sights and attractions while you're in O'Fallon by visiting CarShield Field, Mississippi River, and Alligator Creek Aquatic Center. If you have a bit of extra time while you're in the area, you might want to check out 9-11 Memorial and Golf Headquarters Family Golfplex.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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