Find Resorts & Hotels with Spas in O'Fallon, MO

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on O'Fallon Resorts & Hotels with Spas

Tonight
27 Oct - 28 Oct
Tomorrow
28 Oct - 29 Oct
This weekend
31 Oct - 2 Nov
Next weekend
7 Nov - 9 Nov

Top O'Fallon Resorts & Hotels with Spas

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
8.4 out of 10, Very Good, (1010)
"Great place to stay.Will visit again."
United States
Shameka
The price is AED 684
AED 860 total
includes taxes & fees
28 Oct - 29 Oct
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top O'Fallon Hotel Reviews

La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport

10/10 Excellent
"Updated "
HENRY 1-night trip
Posted 17 hours ago
La Quinta Inn & Suites by Wyndham St. Louis Westport

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in O'Fallon?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the lakeside setting in O'Fallon - worth a picture or two! Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Take in some sights and attractions while you're in O'Fallon by visiting CarShield Field, 9-11 Memorial, and Mississippi River. If you have a bit of extra time while you're in the area, you might want to check out Alligator Creek Aquatic Center and Golf Headquarters.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.