A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

Find Resorts & Hotels with Spas in O'Fallon, MO

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Check availability on O'Fallon Resorts & Hotels with Spas

Our top choices for O'Fallon hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,006 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is AED 542
AED 694 total
includes taxes & fees
3 Aug - 4 Aug
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in O'Fallon

Pool
Breakfast included

Top O'Fallon Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"We stay there almost every month. Great staff and location. Highly recommend them"
Thomas 5-night trip
Posted 8 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

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Frequently asked questions

Looking for a spa hotel in O'Fallon?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the lakeside setting in O'Fallon - worth a picture or two! Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
What's there to see and do in O'Fallon?
Take in some sights and attractions while you're in O'Fallon by visiting CarShield Field, Mississippi River, and Alligator Creek Aquatic Center. If you have a bit of extra time while you're in the area, you might want to check out Golf Headquarters and 9-11 Memorial.
What is a O'Fallon spa hotel?
Spa hotels in O'Fallon provide lodging and have a full on-site spa which offers services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.