Photo by Leonardo De Leon
Find all hotels by Wyndham Hotels in Otay Mesa West, CA from AED 397
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Wyndham Hotels in Otay Mesa West with rates, reviews, and availability. Most hotels are fully refundable.

Wyndham San Diego Bayside
Wyndham San Diego Bayside
8.4 out of 10, Very Good, (5949)
The price is AED 559
AED 754 total
includes taxes & fees
5 Oct - 6 Oct

Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
7.4 out of 10, Good, (4019)
The price is AED 345
AED 397 total
includes taxes & fees
8 Oct - 9 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Otay Mesa West Hotel Reviews

Handlery Hotel
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Otay Mesa West Hotels by Brand
Hotels in Otay Mesa West Neighborhoods
Hotels near popular San Diego Attractions
More Accommodation Types in Otay Mesa West
Explore more hotels
- Hilton San Diego Mission Valley
- Hotel del Coronado, Curio Collection by Hilton
- Pendry San Diego
- Bay Club Hotel & Marina
- The Sofia Hotel
- Legacy Resort Hotel & Spa
- Marriott Marquis San Diego Marina
- Sheraton San Diego Resort
- California Suites Hotel
- Hyatt Regency Mission Bay Spa and Marina
- The Little Italy Hotel Downtown San Diego
- Kings Inn San Diego
- DoubleTree by Hilton Hotel San Diego - Mission Valley
- Omni San Diego Hotel at the Ballpark
- Embassy Suites by Hilton San Diego Bay Downtown
- Paradise Point Resort & Spa
- The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
- The Horton Grand, Downtown/Gaslamp Quarter
- Little Italy Inn - Limited Service Apart Hotel
- GreenTree Inn San Diego Mission Bay