Photo by Pat Long
Find all hotels by Best Western in Panhandle, TX from AED 328
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Compare rooms and suites by Best Western in Panhandle with rates, reviews, and availability. Most hotels are fully refundable.

Best Western Santa Fe
Best Western Santa Fe
8.8 out of 10, Excellent, (954)
The price is AED 328
AED 377 total
includes taxes & fees
18 May - 19 May

Best Western Borger Inn
Best Western Borger Inn
8.4 out of 10, Very Good, (232)
The price is AED 404
AED 465 total
includes taxes & fees
16 May - 17 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Panhandle hotels
Recent reviews of Panhandle hotels

Ashmore Inn & Suites
5/5 Excellent
Great/Safe/Comfortable Stay
"From the check in, to the quality of the room, and comfort of the bed, ALL OF THESE THINGS WERE GREAT!!! Only complaint is getting ice was inconvenient, I was on the 4th floor but the ice machine was only on the 1st floor"
A verified traveler stayed at Ashmore Inn & Suites
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Panhandle Hotels by Brand
Hotels near popular Panhandle Attractions
- Hotels near VW Slug Bug Ranch
- Hotels near Square House Museum
- Hotels near Palo Duro Canyon State Park
- Hotels near Palo Duro Canyon
- Hotels near Amarillo Civic Center
- Hotels near Northwest Texas Hospitals
- Hotels near Wonderland Amusement Park
- Hotels near American Quarter Horse Association
- Hotels near Texas Tech University Health Sciences Center
- Hotels near Baptist St. Anthony's Health Care System
More Hotel Options in Panhandle
Explore more hotels
- Tru By Hilton Amarillo West
- My Place Hotel - Amarillo West/ Medical Center, TX
- Best Western Plus Medical Center
- La Quinta Inn & Suites by Wyndham Amarillo Airport
- Comfort Inn And Suites Amarillo
- Ashmore Inn & Suites
- Best Western Plus Amarillo East Hotel
- The Barfield, Autograph Collection
- Holiday Inn Amarillo West Medical Center by IHG
- La Quinta Inn by Wyndham Amarillo West Medical Center
- Courtyard by Marriott Amarillo Downtown
- Hampton Inn & Suites Amarillo West
- Home2 Suites by Hilton Amarillo
- Residence Inn Amarillo by Marriott
- Holiday Inn Express & Suites Amarillo by IHG
- Courtyard by Marriott Amarillo West/Medical Center
- Motel 6 Amarillo, TX - Airport
- Econo Lodge Amarillo East
- WoodSpring Suites Amarillo East I-40
- TownePlace Suites by Marriott Amarillo West/Medical Center