A train crossing a stone bridge over a river, surrounded by lush greenery.

Perryville Vacation Rentals

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Check prices for these dates

In two weeks
28 Aug - 30 Aug
In two months
9 Oct - 11 Oct
In three months
6 Nov - 8 Nov
In four months
4 Dec - 6 Dec

Our top choices for Perryville vacation rentals

Interior

1. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (4 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is AED 278
AED 586 total
includes taxes & fees
11 Aug - 12 Aug
The Atrium - A Boutique Hotel
Outdoor spa tub

2. Retreat Air - King Bed, Swim Spa & No cleaning fee

Retreat Air - King Bed, Swim Spa & No cleaning fee
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"Great host. Would stay again."
United States
Chris E.
The price is AED 569
AED 702 total
includes taxes & fees
21 Aug - 22 Aug
Retreat Air - King Bed, Swim Spa & No cleaning fee
Coffee/tea maker, full-size fridge, microwave, oven

3. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is AED 740
AED 1,142 total
includes taxes & fees
11 Aug - 12 Aug
Urban Lofts
Interior

4. Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants
Perryville
The price is AED 716
AED 1,164 total
includes taxes & fees
17 Aug - 18 Aug
Downtown Urban Loft above Restaurants
Coffee/tea maker, fridge, microwave, oven

5. Downtown Loft w/ Amazing Bath Tub & Shower

Downtown Loft w/ Amazing Bath Tub & Shower
Perryville
10.0 out of 10, Exceptional, (7 reviews)
"Amazing place. "
United States
Brandy P.
The price is AED 716
AED 1,164 total
includes taxes & fees
11 Aug - 12 Aug
Downtown Loft w/ Amazing Bath Tub & Shower
Property grounds

6. TreeLoft at BaseCamp

TreeLoft at BaseCamp
Perryville
10.0 out of 10, Exceptional, (5 reviews)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
The price is AED 1,139
AED 1,868 total
includes taxes & fees
12 Aug - 13 Aug
TreeLoft at BaseCamp
Private kitchen

7. Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1 review)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is AED 1,873
AED 3,215 total
includes taxes & fees
11 Aug - 12 Aug
Gorgeous, downtown house!
Property grounds

8. New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"Had the best stay. Loved the cozy feel. Loved the hot tub right outside the bedroom. "
United States
Kathleen F.
The price is AED 1,194
AED 1,886 total
includes taxes & fees
24 Aug - 25 Aug
New! Luxury Meets Nature - TreeRise at BaseCamp
TV

9. Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants
Perryville
The price is AED 716
AED 1,149 total
includes taxes & fees
16 Aug - 17 Aug
Downtown Urban Loft above Restaurants
Exterior

10. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (287 reviews)
"The place was easy to find. Cute, clean, and relaxing. It was the perfect stay for our trip. Highly recommend. "
United States
Shayna P.
The price is AED 544
AED 744 total
includes taxes & fees
20 Aug - 21 Aug
Beautiful Modern Loft In Wine Country!
Exterior

11. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is AED 331
AED 602 total
includes taxes & fees
18 Aug - 19 Aug
The Weber Farm - Enjoy a beautiful 100 acre farm!
Dining

12. Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (15 reviews)
"Beautiful and perfect for travelers!!!!!"
United States
Elizabeth
The price is AED 281
AED 699 total
includes taxes & fees
11 Aug - 12 Aug
Cozy 1-bedroom house with AC and WiFi in charming Farmington
Exterior

13. 5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana

5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
Ste. Genevieve
10.0 out of 10, Exceptional, (3 reviews)
"5 Charles Farms was the perfect location to stay following a wedding at Charleville Brewery & Winery. Everything was clean and tidy, and the snacks were a great bonus! Would definitely stay here again if coming to the area."
United States
Nicole T.
The price is AED 654
AED 964 total
includes taxes & fees
17 Aug - 18 Aug
5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
Exterior

14. Cozy 2-bedroom cottage in charming Ste. Genevieve

Cozy 2-bedroom cottage in charming Ste. Genevieve
Ste. Genevieve
10.0 out of 10, Exceptional, (4 reviews)
"Great location!"
United States
Katie M.
The price is AED 551
AED 685 total
includes taxes & fees
12 Aug - 13 Aug
Cozy 2-bedroom cottage in charming Ste. Genevieve
Exterior

15. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (154 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
The price is AED 878
AED 1,293 total
includes taxes & fees
12 Aug - 13 Aug
Silo Farm Haus- located in the heart of wine country!
1 bedroom, bed sheets

16. Conestoga Covered Wagon on Working Farm - Willowmere

Conestoga Covered Wagon on Working Farm - Willowmere
Fredericktown
The price is AED 423
AED 895 total
includes taxes & fees
11 Aug - 12 Aug
Conestoga Covered Wagon on Working Farm - Willowmere
Coffee/tea maker, fridge, microwave, oven

17. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (25 reviews)
"Very nice stay we enjoyed would definitely stay again"
United States
Ben C.
The price is AED 444
AED 875 total
includes taxes & fees
11 Aug - 12 Aug
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Exterior

18. 5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana

5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
New Offenburg
The price is AED 646
AED 957 total
includes taxes & fees
2 Sep - 3 Sep
5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
Living area

19. St Francis River: The Blue Yurt and Hot Tub

St Francis River: The Blue Yurt and Hot Tub
Fredericktown
8.8 out of 10, Excellent, (26 reviews)
"Loved this rental - great property!"
United States
Julie S.
The price is AED 459
AED 794 total
includes taxes & fees
11 Aug - 12 Aug
St Francis River: The Blue Yurt and Hot Tub
Interior

20. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (13 reviews)
"Our stay was amazing. Everything was so clean organized, and anything you would possibly need was in the room. We will definitely be staying there again when in the area!!"
United States
Karen P.
The price is AED 551
AED 663 total
includes taxes & fees
11 Aug - 12 Aug
Villa B offers peace and quiet with beautiful views of the countryside.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Perryville Hotel Reviews

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"Breakfast menu was limited but ok for most people. The room was very comfortable, cozy and clean."
Lois 1-night trip
Posted 23 hours ago
Tru By Hilton Cape Girardeau

Frequently asked questions

Can I find a vacation rental in Perryville?

Yes, you can find vacation rentals near top local attractions in Perryville, or you can choose a more secluded option if you'd like a relaxing place to stay. Perryville is known for its wineries and golf courses. Make sure you have time to check out the coffeehouses and festivals during your trip.

What are some of the best vacation rentals that Perryville has to offer?

Silo Farm Haus- located in the heart of wine country!: This vacation home rental outside of Perryville is in a rural location and offers a Smart TV to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Perryville?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Perryville stay.

What’s there to see and do in Perryville?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. While here, National Shrine of Our Lady of the Miraculous Medal and Saint Marys Lake are other places worth a visit.

What’s a vacation rental in Perryville like?

Vacation rentals are privately owned properties you can book for short or long periods in Perryville. Vacation rentals offer amenities such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a clean environment, vacation rentals can provide a sense of security away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for family gatherings.