A calm river surrounded by dense trees reflecting the greenery.

Vacation Homes in Pike County

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Check prices for these dates

In two weeks
30 Oct - 1 Nov
In two months
11 Dec - 13 Dec
In three months
8 Jan - 10 Jan
In four months
5 Feb - 7 Feb

Our top choices for Pike County vacation homes

A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

1. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (68 reviews)
"Great location for downtown exploring."
United States
Lisa B.
The price is AED 415
AED 688 total
includes taxes & fees
3 Nov - 4 Nov
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A modern living room with two dark sofas, a glass coffee table, and a decorative plant.

2. Amazing Hannibal Home - Eitaly’s on Paris

Amazing Hannibal Home - Eitaly’s on Paris
Hannibal
6.4 out of 10, (16 reviews)
"House is located very close to Main Street which features lots of shops, food, and historical sights in close proximity! The inside is very clean and the owner has thought of everything you could possibly need! We stayed here for the second time this year, in fact."
United States
Heather N.
Amazing Hannibal Home - Eitaly’s on Paris
A porch with a wicker chair, a rocking chair, and a table with a vase of flowers.

3. Charming 2-bedroom house at Mark Twain Lake

Charming 2-bedroom house at Mark Twain Lake
Stoutsville
10.0 out of 10, Exceptional, (43 reviews)
"Very clean and nice spot for a fishing vacation"
United States
Melissa H.
Charming 2-bedroom house at Mark Twain Lake
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

4. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (225 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
The price is AED 477
AED 907 total
includes taxes & fees
13 Oct - 14 Oct
Peaceful, Country Cottage with Open Floor Plan
A lodge with a stone exterior, large windows, and a green roof.

5. Mark Twain lake getaway at Blue Lagoon!

Mark Twain lake getaway at Blue Lagoon!
Monroe City
10.0 out of 10, Exceptional, (52 reviews)
"Place was great for our fishing tournament."
United States
Richard P.
Mark Twain lake getaway at Blue Lagoon!
A living room with a sofa, a coffee table, and a wooden door leading to a kitchen area with a refrigerator, microwave, and cabinets.

6. Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown
Hannibal
9.6 out of 10, Exceptional, (23 reviews)
"It was very cozy and well stocked and organized as well! Neat experience to stay in a historic home like this! "
United States
Ashley S.
Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown
A modern kitchen with a coffee machine, wooden countertop, and a large mirror.

7. The Chicken Coop on Highway H

The Chicken Coop on Highway H
Troy
10.0 out of 10, Exceptional, (30 reviews)
"This was the most relaxing place that I have ever stayed. The host made the stay feel very personalized with a welcome note. I will definitely stay here again in the future. Highly recommend this for anyone wanting a relaxing stay. Thank you for being a gracious host."
United States
Brenda A.
The Chicken Coop on Highway H
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

8. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.6 out of 10, Exceptional, (27 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
The price is AED 618
AED 943 total
includes taxes & fees
13 Oct - 14 Oct
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A modern interior with a sectional leather sofa, a dining area with wooden cabinets, and a kitchen with a refrigerator.

9. Relaxing, Quiet get away where you can enjoy the outdoors.

Relaxing, Quiet get away where you can enjoy the outdoors.
Elsberry
10.0 out of 10, Exceptional, (36 reviews)
"This is the 3rd time that our family has stayed here. It is perfect for our family. Great place!"
United States
Pam S.
Relaxing, Quiet get away where you can enjoy the outdoors.
A spacious living area with a large wooden dining table, comfortable seating, and a staircase leading to an upper level.

10. Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake

Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake
Monroe City
10.0 out of 10, Exceptional, (9 reviews)
"The property was perfect for sitting and relaxing at the end of the day, and the owners were very helpful and communicative. :-)"
United States
Beth B.
Totally Renovated Home on 5 Acres - Just 4 Miles From Mark Twain Lake
A bedroom with a bed, a chair, a window with curtains, a wall-mounted mirror, and a painting.

11. Cozy 3 bed, 2 bath home close to historic downtown Hannibal

Cozy 3 bed, 2 bath home close to historic downtown Hannibal
Hannibal
10.0 out of 10, Exceptional, (70 reviews)
"Clean and cozy just like advertised! Four ladies, very comfortable stay! "
United States
Melissa W.
Cozy 3 bed, 2 bath home close to historic downtown Hannibal
A laundry area with washing machines, a wooden cabinet, and a bar stool area.

12. Papa's Cabin - 40 acres & 5 acre lake!

Papa's Cabin - 40 acres & 5 acre lake!
Middletown
10.0 out of 10, Exceptional, (4 reviews)
"Overall stay was amazing! The property was just like described and the hostess was easy to communicate with."
United States
Prisilla B.
Papa's Cabin - 40 acres & 5 acre lake!
A set of outdoor steps leading to a building entrance, with a white railing and a decorative flag.

13. Hannibal House ~ Walking Distance From Historic District

Hannibal House ~ Walking Distance From Historic District
Hannibal
8.4 out of 10, Very good, (55 reviews)
"Close to downtown. "
United States
Paula L.
Hannibal House ~ Walking Distance From Historic District
A living room with a fireplace, a sofa, a table, and a staircase leading to another room.

14. Admiral Fuqua House - Large downtown Hannibal Home

Admiral Fuqua House - Large downtown Hannibal Home
Hannibal
9.6 out of 10, Exceptional, (39 reviews)
"Fun Fourth of July Weekend!Perfect location for holiday event!"
United States
Betty M.
Admiral Fuqua House - Large downtown Hannibal Home
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

15. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21 reviews)
"House was perfect for our stay."
United States
Brent W.
The price is AED 361
AED 1,094 total
includes taxes & fees
15 Oct - 16 Oct
Modern and comfy home five minutes from downtown
A modern kitchen with white cabinetry, a stainless steel sink, and a dishwasher.

16. Historic Main Street Cottage

Historic Main Street Cottage
Troy
10.0 out of 10, Exceptional, (46 reviews)
"We have stayed before and come back when we see family in the area. Great as usual."
United States
Ivy B.
Historic Main Street Cottage
A spacious room with hardwood flooring, a grand piano, a comfortable armchair, and a chandelier.

17. The Yellow Rose Historic Home

The Yellow Rose Historic Home
Louisiana
9.8 out of 10, Exceptional, (19 reviews)
"Everything was great!"
United States
Brendan R.
The price is AED 767
AED 1,162 total
includes taxes & fees
13 Oct - 14 Oct
The Yellow Rose Historic Home
A bedroom with a large bed, a fireplace, a TV, and a window.

18. Experience Hannibal, MO from this historic home built in 1844

Experience Hannibal, MO from this historic home built in 1844
Hannibal
10.0 out of 10, Exceptional, (18 reviews)
"Very nice charming historic home. Close to all the places we wanted to visit. Would recommend to my friends."
United States
Marcia L.
Experience Hannibal, MO from this historic home built in 1844
Two chairs and a small table outside a building with a brick wall and a window.

19. Historic Charm Meets Modern Comfort in This 1906 Historic Home

Historic Charm Meets Modern Comfort in This 1906 Historic Home
Hannibal
10.0 out of 10, Exceptional, (1 review)
"It was a beautiful house with enough room for everyone. The location was great!"
United States
Tara
Historic Charm Meets Modern Comfort in This 1906 Historic Home
A house with a covered porch, a stone fireplace, and a view of a lake.

20. Newly Remodeled 3BR Riverfront Apartment w/ WiFi & Private Access

Newly Remodeled 3BR Riverfront Apartment w/ WiFi & Private Access
Hamburg
10.0 out of 10, Exceptional, (2 reviews)
"Very nice, everything was brand new, lots of nature. Nature lovers this is your place. Had a deer with triplets in the front yard one evening. If you are looking for a place to get away from it all, you will love this place."
United States
Bill G.
Newly Remodeled 3BR Riverfront Apartment w/ WiFi & Private Access
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pike County Hotel Reviews

Bay Inn & Suites Troy

Bay Inn & Suites Troy

10/10 Excellent
"The staff was exceptionally helpful & the hotel was newly remodeled & very clean."
Marsha 1-night trip
Posted 9 hours ago
Bay Inn & Suites Troy

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