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Check availability on Rochester Business Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Rochester business-friendly hotels

A Comfort Inn & Suites hotel with a modern design, featuring a prominent signage and a parking lot.

1. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,009 reviews)
"Surprisingly clean, pleasant staff, comfortable and quiet. Will definitely stay again next time I am in town"
United States
Terri
The price is AED 262
AED 302 total
includes taxes & fees
27 Nov - 28 Nov
Comfort Inn & Suites Rochester South Mayo Clinic
A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

2. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,013 reviews)
"The staff was extremely friendly!"
United States
Ashley
The price is AED 247
AED 285 total
includes taxes & fees
28 Nov - 29 Nov
Econo Lodge Mayo Clinic Area
A modern dining area with high tables, chairs, and pendant lighting.

3. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean room great facilities."
United States
Mark
The price is AED 376
AED 433 total
includes taxes & fees
6 Nov - 7 Nov
Hampton Inn & Suites Rochester-North
An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

4. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,007 reviews)
"Nice stay"
United States
Arlan
The price is AED 433
AED 499 total
includes taxes & fees
27 Nov - 28 Nov
Hyatt House Rochester/Mayo Clinic Area
An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

5. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, very nice staff and nice atmosphere."
United States
howard
The price is AED 403
AED 464 total
includes taxes & fees
7 Nov - 8 Nov
Home2 Suites by Hilton Rochester Mayo Clinic Area
A modern indoor patio with a fire feature, seating, and large windows.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (1,008 reviews)
"Great hotel and very clean!"
United States
James
The price is AED 419
AED 532 total
includes taxes & fees
6 Nov - 7 Nov
EVEN Hotel Rochester - Mayo Clinic Area by IHG
An outdoor patio area with a concrete floor, wooden fence, and string lights.

7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (749 reviews)
"The staff was extremely helpful making for a comfortable stay."
United States
Brien
The price is AED 426
AED 491 total
includes taxes & fees
6 Nov - 7 Nov
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Room

8. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1,579 reviews)
"Very nice we had a great stay"
United States
blake
The price is AED 277
AED 319 total
includes taxes & fees
8 Nov - 9 Nov
AmericInn by Wyndham Rochester Near Mayo Clinic
A modern hotel lobby with a reception desk, seating area, and a dining space.

9. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,001 reviews)
"Nice location, easy access and good breakfast."
United States
Rick
The price is AED 316
AED 364 total
includes taxes & fees
7 Nov - 8 Nov
Holiday Inn Express Rochester South - Mayo Area by IHG
A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

10. Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,002 reviews)
"Everyone was very helpful even the guests. Breakfast was good. Parking was great."
United States
Elaine
The price is AED 441
AED 507 total
includes taxes & fees
29 Oct - 30 Oct
Brentwood Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Rochester Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"A"
Darlene 2-night trip
Posted 1 hour ago
Med City Inn & Suites - Mayo Clinic Area