The Best Business Hotels in Rochester, MN from AED 282 in 2026 | Expedia

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Check availability on Rochester Business Hotels

Tonight

20 Oct - 21 Oct

Tomorrow

21 Oct - 22 Oct

This weekend

23 Oct - 25 Oct

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Our top choices for Rochester business-friendly hotels

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

1. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

United States

James

AED 419

AED 532 total

includes taxes & fees

23 Oct - 24 Oct

A modern dining area with high tables, chairs, and pendant lighting.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

2. Hampton Inn & Suites Rochester-North

Rochester

United States

Mark

AED 376

AED 433 total

includes taxes & fees

6 Nov - 7 Nov

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

An outdoor dining area with wooden beams, tables, and chairs.

3. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

United States

Hernan

AED 393

AED 452 total

includes taxes & fees

23 Oct - 24 Oct

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

4. Econo Lodge Mayo Clinic Area

Rochester

United States

Ashley

AED 245

AED 282 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

Property amenity

5. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

United States

Brien

AED 443

AED 510 total

includes taxes & fees

6 Nov - 7 Nov

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

6. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

United States

Christine

AED 419

AED 483 total

includes taxes & fees

23 Oct - 24 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

7. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Canada

Cory

AED 503

AED 579 total

includes taxes & fees

6 Nov - 7 Nov

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A hotel room with two beds, a desk, a chair, and a mirror.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A bar with wooden stools and a neon sign.

8. AmericInn by Wyndham Rochester Near Mayo Clinic

Rochester

United States

blake

AED 268

AED 309 total

includes taxes & fees

25 Oct - 26 Oct

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Top Rochester Hotel Reviews

Aspen Select

Aspen Select

8/10 Good

"Small area to park in and not easy to get to"

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good

"Everything is immaculately clean, staff is friendly and helpful. Good morning breakfast is just a very basics, bagels muffins toast cereal. But it worked out well"

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"It was a great experience"

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Has been updated a bit since our last stay. Has been clean and newer items in the room. Staff always helpful. Breakfast dinning has been upgraded too! nice to see the change in the stations. Excellent to take the subway to Mayo apts. Caribou coffee downstairs, Jimmy John's, Chinese in the hotel restaurant. Have stayed here 15+ times in the past 2 years. Would recommend."

Quality Inn near Medical Center

Quality Inn near Medical Center

8/10 Good

"Property seemed to be in the middle of an upgrade"