The Best Business Hotels in Rochester, MN from AED 297 in 2026 | Expedia

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Check availability on Rochester Business Hotels

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16 Oct - 18 Oct

Our top choices for Rochester business-friendly hotels

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

1. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

United States

Rici

AED 433

AED 549 total

includes taxes & fees

6 Nov - 7 Nov

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A laundry area with two Whirlpool washers and a dryer, a wooden shelf above, and a white ceiling.

A modern living room with a sofa, two armchairs, a coffee table, and a large window offering a view of the outdoors.

A gym with treadmills, elliptical machines, and a stationary bike.

2. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

United States

Phil

AED 318

AED 366 total

includes taxes & fees

10 Oct - 11 Oct

A modern dining area with high tables, chairs, and pendant lighting.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

3. Hampton Inn & Suites Rochester-North

Rochester

United States

Dr. Tim

AED 358

AED 413 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A restaurant interior with wooden tables, chairs, and a stone wall.

4. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

United States

Christina

AED 396

AED 456 total

includes taxes & fees

10 Oct - 11 Oct

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

A modern hotel room with a bed, desk, and kitchenette.

A modern restaurant with a counter, seating area, and a TV screen.

5. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

United States

Vickie

AED 449

AED 517 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern bar area with seating and a counter.

6. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

United States

Kathy

AED 433

AED 499 total

includes taxes & fees

17 Oct - 18 Oct

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

Property amenity

7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

United States

Jon

AED 410

AED 472 total

includes taxes & fees

17 Oct - 18 Oct

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

An outdoor dining area with wooden beams, tables, and chairs.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

8. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

United States

thomas

AED 393

AED 452 total

includes taxes & fees

24 Oct - 25 Oct

View all properties

Top Rochester Hotel Reviews

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Staff was good, rooms were clean but needing some updates"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Excellent location. Great shuttle service to mayo gonna. No working wifi in my room but other than that was fine."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"We had a very nice stay. We were able to Walk to Mayo and enjoyed the attached Twigs restaurant."

Aspen Select

Aspen Select

10/10 Excellent

"Very close to the North entrance of St. Mary's. Construction is there but still very convenient."

Brentwood Inn & Suites

Brentwood Inn & Suites

10/10 Excellent

"Staff was very helpful and kind. Desk chair worn and could use a replacement-normally would not care but was working remote while there. Wi-Fi great"

Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent

"The staff were amazingly friendly and helpful. Joey went above and beyond to adjust my room. I loved getting a cold bottle of water at check in."