The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

A grand room with a chandelier, a fireplace, and ornate furniture.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

AED 506

AED 580 total

includes taxes & fees

9 Nov - 10 Nov

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

AED 1,196

AED 1,391 total

includes taxes & fees

12 Oct - 13 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Grace

AED 426

AED 587 total

includes taxes & fees

12 Oct - 13 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A pool table in a room with patterned carpet, a dining table with chairs, and a red sofa.

4. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

AED 724

AED 831 total

includes taxes & fees

18 Oct - 19 Oct

A two-story building with a white exterior, a red door, and large windows.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A hot tub with a wooden fence and a brick building in the background.

5. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

AED 562

AED 645 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.

6. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

Michael

AED 856

AED 1,000 total

includes taxes & fees

18 Oct - 19 Oct

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

7. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

John

AED 933

AED 1,090 total

includes taxes & fees

9 Nov - 10 Nov

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

A gym with treadmills and a rowing machine, large windows, and a city view.

A spacious lobby with a stone fireplace, comfortable seating, large windows, and a modern design.

The Westin hotel entrance with a glass facade and a sign indicating it's now open.

8. The Westin Buffalo

Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute

Sarah

AED 871

AED 1,016 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

9. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Julian

AED 579

AED 675 total

includes taxes & fees

12 Oct - 13 Oct

A modern hotel lobby with a bar area, seating, and a large TV screen.

A modern hotel lobby with seating areas, a flat-screen TV, and a bookshelf.

A modern restaurant with a long counter, bar stools, and a refrigerated display.

A modern building with a Starbucks on the ground floor, featuring large windows and a flat roof.

10. Residence Inn by Marriott Buffalo Downtown

Allentown, 0.7 km from Roswell Park Cancer Institute

Karen

AED 871

AED 1,017 total

includes taxes & fees

18 Oct - 19 Oct

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

11. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

AED 746

AED 871 total

includes taxes & fees

18 Oct - 19 Oct

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A breakfast buffet with various pastries, fruits, and bread.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

12. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Gerald D

AED 621

AED 725 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

13. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

John

AED 559

AED 652 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

A lobby area with a reception desk, seating arrangements, a coffee station with beverages and snacks, and a decorative wall with a fireplace.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

14. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

AED 584

AED 682 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

A Starbucks coffee shop with a modern design, featuring wooden furniture and a spacious layout.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

15. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Joseph

AED 503

AED 587 total

includes taxes & fees

25 Oct - 26 Oct

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

A modern hotel room with a fireplace, a flat-screen TV, a sofa, and a bed.

A spacious lobby with a central seating area, large columns, and a chandelier.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

16. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Angela

AED 568

AED 663 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A hotel room with a large bed, a TV mounted on the wall, a city view through the window, and a wooden shelf.

A modern hotel room with a dining area, a large bed, and a view of the city.

A modern bar area with seating, a counter with bottles, and a large window.

17. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Michelle

AED 653

AED 762 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A buffet with various food items, including omelets and other dishes, served in metal trays.

A gym with exercise equipment, a mirror, and a television.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

18. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

Charles

AED 562

AED 656 total

includes taxes & fees

19 Oct - 20 Oct

A lobby with a staircase, seating area, and a view of the outdoors.

A hotel room with two beds, a desk, a television, and a window.

A bathroom with a toilet, sink, and shower curtain.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

19. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Thomas

AED 388

AED 445 total

includes taxes & fees

25 Oct - 26 Oct

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

20. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute

Anthony T

AED 804

AED 939 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,004 reviews	View
Buffalo Guesthouse	9.4 Exceptional 219 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

10/10 Excellent

"Staff was great. Loved the room. The breakfast was amazing. Not used to the city so the sounds of city life woke us up a couple times. Overall great experience"

Buffalo Guesthouse

10/10 Excellent

"First time in Buffalo. I was here for the game. Allentown is apparently a pretty safe neighborhood, which is why I chose this place. You can either stay here or pay $200 more dollars for a more sterile environment across the street. Anyways, the room is not the best I've ever stayed at, but definitely not the worst. To give you an idea -- the doors are lock & key (and don't block sound), the bathroom tiles were a bit chippy, there's no space in the bathroom to put your toiletries bag except on top of the toilet, But it was clean. If you need a meal, go to Cafe 59 down the street and get the soup & salad. If you're going to the game, here's a little secret: there's a shuttle from the Utica Station to the New Highmark Stadium. To get to Utica Station, just walk 20 minutes via Linwood Ave, a safer street. (Utica Station is a little rough, so don't bring your whole wallet, just your $5 bills to get on the shuttle.) Would I stay here again? Yes. Would I put my parents in a room here? Probably not."

Lenox Hotel and Suites

10/10 Excellent

"Enjoyed our stay"

Cozy & Modern Victorian in Historic Allentown, Buffalo

10/10 Excellent

"Brandon's home was the absolute perfect location for a long weekend in Buffalo. We were able to walk just steps to one of our favorite restaurants (Gabriel's Gate), and all the bars and markets on Allen Street/Elmwood Ave.. The house had everything we needed and was decorated/furnished so nicely. The beds were super comfy, I slept like baby. The backyard garden was an oasis and I worked for two days from the table in the backyard, wifi was great! The neighbor was very nice too, which is par for the course in Buffalo. Love this city!! Go Bills."

Hilton Garden Inn Buffalo Downtown

8/10 Good

"I didn't like that it was cashless. Also the lobby coffee, while cheap, was not good."

Hampton Inn & Suites Buffalo Downtown

10/10 Excellent

"Clean Comfortable Good breakfast"

The Westin Buffalo

10/10 Excellent

"."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"Loved it, we actually rerouted our return trip home to stay here again :)"

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Friendly staff, excellent breakfast buffet, convenient location. I would definitely stay here again."

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from AED 445

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. The Mansion On Delaware Ave

5. Buffalo Guesthouse

6. Buffalo Marriott at LECOM HARBORCENTER

7. Curtiss Hotel, an Ascend Collection Hotel

8. The Westin Buffalo

9. Wyndham Garden Buffalo Downtown

10. Residence Inn by Marriott Buffalo Downtown

11. Courtyard Buffalo Downtown / Canalside

12. Hampton Inn & Suites Buffalo Downtown

13. Best Western on the Avenue

14. Hilton Garden Inn Buffalo Downtown

15. Hyatt Regency Buffalo / Hotel and Conference Center

16. Hotel at the Lafayette Trademark Collection by Wyndham

17. Embassy Suites Buffalo

18. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

19. Lenox Hotel and Suites

20. Aloft by Marriott Buffalo Downtown

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

Buffalo Guesthouse

Lenox Hotel and Suites

Cozy & Modern Victorian in Historic Allentown, Buffalo

Hilton Garden Inn Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

The Westin Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Residence Inn by Marriott Buffalo Downtown

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions