Search Vacation Homes in Roxboro

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
27 Mar - 29 Mar
In two months
8 May - 10 May
In three months
5 Jun - 7 Jun
In four months
3 Jul - 5 Jul

Our top choices for Roxboro vacation homes

Exterior

4BR Farm House | Chef's Kitchen | Firepit

4BR Farm House | Chef's Kitchen | Firepit
Bahama
10.0 out of 10, Exceptional, (1 review)
"We had the most wonderful stay at this beautiful farmhouse while celebrating my daughter's 17th birthday. The home was spotless, charming, and even more stunning in person than in the photos. One of the biggest highlights was the chef's kitchen-spacious, beautifully designed, and fully stocked. Emily went above and beyond to make sure everything was perfect, and we truly appreciated the attention to detail. My daughter and her friends absolutely loved it-there was plenty of room to relax,...
United States
Christy H.
The price is AED 1,001
AED 2,470 total
includes taxes & fees
12 Mar - 13 Mar
4BR Farm House | Chef's Kitchen | Firepit
Living area

3-bedroom house in fantastic North Durham with cool AC and comfort

3-bedroom house in fantastic North Durham with cool AC and comfort
Durham
3-bedroom house in fantastic North Durham with cool AC and comfort
Dining

Dog-Friendly Lakeside Escape w/ Hammock & Fire Pit

Dog-Friendly Lakeside Escape w/ Hammock & Fire Pit
Bahama
Dog-Friendly Lakeside Escape w/ Hammock & Fire Pit
Outdoor dining

*Pet Friendly* Charming-Single story | Fenced Yard, Outdoor Dining, Near Duke

*Pet Friendly* Charming-Single story | Fenced Yard, Outdoor Dining, Near Duke
Durham
10.0 out of 10, Exceptional, (1 review)
*Pet Friendly* Charming-Single story | Fenced Yard, Outdoor Dining, Near Duke
Interior

Cozy Ranch New Build 3 bed 2 bath

Cozy Ranch New Build 3 bed 2 bath
Durham
9.8 out of 10, Exceptional, (21 reviews)
"great location to the city"
United States
joe d.
The price is AED 665
AED 1,559 total
includes taxes & fees
1 Apr - 2 Apr
Cozy Ranch New Build 3 bed 2 bath
Microwave, oven, stovetop, dishwasher

Cozy & Stylish Retreat Near Duke- Quiet Unit C

Cozy & Stylish Retreat Near Duke- Quiet Unit C
Durham
10.0 out of 10, Exceptional, (1 review)
"This new, sparkling, thoughtfully outfitted home made our girl’s weekend just perfect. The location was easy to access off the interstate, close to plenty of shopping, but tucked into a quiet little alcove that made it feel very private. We enjoyed a walk on the Duke campus, then explored the Hillsboro arts district. It was all within a few miles and so easy. We would definitely return and completely recommend this VRBO! "
United States
Dearsley V.
Cozy & Stylish Retreat Near Duke- Quiet Unit C
Interior

Charming 3-bedroom house, in pleasant North Durham

Charming 3-bedroom house, in pleasant North Durham
Durham
8.0 out of 10, Very Good, (1 review)
"house has nice open space , excellent kitchen space as well. I have given owner some suggestions on improvements with regards to supplies and some better instructions . Overall an excellent place to stay and would not hesitate to stay again if in Durham again"
United States
neville c.
Charming 3-bedroom house, in pleasant North Durham
Private kitchen

Duke Hospital 3BR Zero Stairs, Wheelchair access ramp with handrails

Duke Hospital 3BR Zero Stairs, Wheelchair access ramp with handrails
Durham
The price is AED 328
AED 1,243 total
includes taxes & fees
15 Mar - 16 Mar
Duke Hospital 3BR Zero Stairs, Wheelchair access ramp with handrails
Room

Duke Stayhouse

Duke Stayhouse
Durham
Duke Stayhouse
Private kitchen

Duke Captains’ Quarters 3BR 2.5BA @ American Village

Duke Captains’ Quarters 3BR 2.5BA @ American Village
Durham
8.0 out of 10, Very Good, (8 reviews)
"The home is older, but the beds are comfortable, the home is adequately furnished, and the kitchen is fully stocked. The location is close to so many restaurants and stores - perfect for using delivery services such as Door Dash. The neighborhood was quiet and safe. The owners were responsive."
United States
April R.
Duke Captains’ Quarters 3BR 2.5BA @ American Village
Terrace/patio

Duke Hospital Zero-Step 1BR

Duke Hospital Zero-Step 1BR
Durham
9.4 out of 10, Exceptional, (8 reviews)
"Tge location was perfect for my appointments and shopping I needed to do. Very quiet and peaceful location."
United States
Jasper R.
Duke Hospital Zero-Step 1BR
Dining

10min to Cameron | Near Duke Hospital, Univ, Dtwn

10min to Cameron | Near Duke Hospital, Univ, Dtwn
Durham
10.0 out of 10, Exceptional, (1 review)
"We very much enjoyed our stay at this property. The rental space looks like it was recently built and the furniture, household goods and appliances all look like they are brand new. The host sent us suggestions for things to do in the area and places to eat. I highly recommend this lovely VRBO."
United States
Teri P.
10min to Cameron | Near Duke Hospital, Univ, Dtwn
Living area

10min to Duke University + downtown. Dogs welcome!

10min to Duke University + downtown. Dogs welcome!
Durham
10.0 out of 10, Exceptional, (16 reviews)
"The place was as advertised and in a good location. We enjoyed our stay"
United States
Malik H.
10min to Duke University + downtown. Dogs welcome!
Interior

Charming remodeled historic home in the small town of South Boston, Virginia.

Charming remodeled historic home in the small town of South Boston, Virginia.
South Boston
10.0 out of 10, Exceptional, (5 reviews)
"The property was not available, but the owner took great care of us and made sure that we had everything we needed. The owner was great and we were well pleased. "
United States
Ricky L.
The price is AED 661
AED 1,244 total
includes taxes & fees
11 Mar - 12 Mar
Charming remodeled historic home in the small town of South Boston, Virginia.
Fridge, microwave, oven, stovetop

Modern And Cozy House In The Heart Of Hillsborough

Modern And Cozy House In The Heart Of Hillsborough
Hillsborough
10.0 out of 10, Exceptional, (2 reviews)
"Great location and included everything we needed "
United States
Debra Delois C.
The price is AED 514
AED 1,258 total
includes taxes & fees
11 Mar - 12 Mar
Modern And Cozy House In The Heart Of Hillsborough
Fridge, microwave, oven, stovetop

Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.

Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.
Semora
10.0 out of 10, Exceptional, (20 reviews)
"Great quiet location with scenic lake view"
United States
Keith R.
The price is AED 826
AED 1,516 total
includes taxes & fees
23 Mar - 24 Mar
Charming 4-bedroom 3-bath house on beautiful Hyco Lake with boat dock.
Exterior

Lake Days Getaway Sum

Lake Days Getaway Sum
Hillsborough
10.0 out of 10, Exceptional, (1 review)
"The location did not disappoint. On a beautiful lake. Very quiet. We spent a lot of time just sitting on the dock with a cup of coffee or a glass of wine. Our group was compromised of 10 adults and one 6 yr old. My niece was thrilled with the bunk beds. In the same room with the bunk beds are some books for reading and a reading nook. She absolutely loved the nook. The sunroom is absolutely beautiful. Tastefully decorated. And the view from the sunroom is stunning. I did reach out to the host...
United States
Diane S.
The price is AED 1,410
AED 3,347 total
includes taxes & fees
11 Mar - 12 Mar
Lake Days Getaway Sum
Exterior

Beautiful Modern Home Retreat with Private Lake on 15 acres

Beautiful Modern Home Retreat with Private Lake on 15 acres
Hillsborough
10.0 out of 10, Exceptional, (1 review)
"We had a wonderful stay at this Hillsboro VRBO! The home was spotless and well-maintained, making it easy to relax and enjoy our time. The location was perfect—close to everything we needed, yet peaceful enough to truly unwind. It was an ideal spot for a girlfriends’ getaway, and we loved how comfortable and inviting it felt. We left feeling refreshed and full of great memories. Highly recommend"
United States
Christi G.
The price is AED 764
AED 1,867 total
includes taxes & fees
11 Mar - 12 Mar
Beautiful Modern Home Retreat with Private Lake on 15 acres
Property grounds

Lakefront Hygge: Dock|Marine Hammock|Screen Porch

Lakefront Hygge: Dock|Marine Hammock|Screen Porch
Prospect Hill
9.2 out of 10, Wonderful, (30 reviews)
"Great stay, house is super cute and comfortable! "
United States
Ashley T.
The price is AED 441
AED 1,133 total
includes taxes & fees
11 Mar - 12 Mar
Lakefront Hygge: Dock|Marine Hammock|Screen Porch
Smart TV, DVD player, stereo

Fortress of Solitude

Fortress of Solitude
prospect hill
10.0 out of 10, Exceptional, (7 reviews)
"Lovely house and beautiful property!"
United States
Elizabeth W.
The price is AED 437
AED 943 total
includes taxes & fees
10 Apr - 11 Apr
Fortress of Solitude
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Eid al-Fitr Sale

Members save up to 40% on hotels. Plan this year’s big trip and save.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Roxboro Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

4/10 Poor
"Fire alarm went off late at night, none of the workers acknowledged it or explained what was going on after the fact. The lady working that night was rude and barely acknowledged me when I asked what caused it to go off. Room was decent and clean but had a very old smell to it. Won’t be back."
Mason 1-night trip
Posted 9 hours ago
Comfort Inn & Suites Durham near Duke University