The Alamo, a historic building with a prominent arched entrance and a flagpole in front.

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Our top choices for Jefferson hotels

1. Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center
2.5 star property
2.6 km from Jefferson
7.2 out of 10, Good, (2,231 reviews)
"Great hotel,great staff"
United States
Masumbuko
The price is AED 205
AED 254 total
includes taxes & fees
25 Aug - 26 Aug
Comfort Inn and Suites Near Medical Center

2. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District, 4.9 km from Jefferson
8.6 out of 10, Excellent, (1,149 reviews)
"Great hotel"
United States
Mario
The price is AED 342
AED 407 total
includes taxes & fees
18 Sep - 19 Sep
San Antonio Marriott Northwest Medical Center

3. DoubleTree by Hilton San Antonio Downtown

DoubleTree by Hilton San Antonio Downtown
4.0 star property
5.4 km from Jefferson
8.4 out of 10, Very Good, (1,011 reviews)
"It was a great location easily walkable to everything"
United States
Vijay
The price is AED 328
AED 388 total
includes taxes & fees
26 Aug - 27 Aug
DoubleTree by Hilton San Antonio Downtown

4. La Quinta Inn by Wyndham San Antonio Market Square

La Quinta Inn by Wyndham San Antonio Market Square
3.0 star property
Downtown San Antonio, 5.5 km from Jefferson
8.0 out of 10, Very Good, (1,352 reviews)
"Very clean room and convenient to walk to the Market Square as well as Mi Tierra Restaurant."
United States
LETICIA
The price is AED 262
AED 309 total
includes taxes & fees
23 Aug - 24 Aug
La Quinta Inn by Wyndham San Antonio Market Square

5. InterContinental San Antonio Riverwalk by IHG

InterContinental San Antonio Riverwalk by IHG
4.5 star property
Downtown San Antonio, 5.6 km from Jefferson
9.2 out of 10, Wonderful, (759 reviews)
"Great location loved it"
United States
ALMA
The price is AED 558
AED 808 total
includes taxes & fees
24 Aug - 25 Aug
InterContinental San Antonio Riverwalk by IHG

6. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District, 6.3 km from Jefferson
8.4 out of 10, Very Good, (3,593 reviews)
"Great location and very clean/nice."
United States
Melissa
The price is AED 326
AED 386 total
includes taxes & fees
20 Aug - 21 Aug
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

7. Embassy Suites San Antonio Riverwalk-Downtown

Embassy Suites San Antonio Riverwalk-Downtown
3.5 star property
Downtown San Antonio, 5.8 km from Jefferson
9.0 out of 10, Wonderful, (1,486 reviews)
"Breakfast was great ,staff was amazing and the happy hour just rocks"
United States
Blake
The price is AED 509
AED 605 total
includes taxes & fees
6 Sep - 7 Sep
Embassy Suites San Antonio Riverwalk-Downtown

8. AC Hotel by Marriott San Antonio Riverwalk

AC Hotel by Marriott San Antonio Riverwalk
4.0 star property
Main - Military Plaza, 5.9 km from Jefferson
9.0 out of 10, Wonderful, (1,262 reviews)
"Great location"
United States
Jose Martinez
The price is AED 433
AED 512 total
includes taxes & fees
27 Aug - 28 Aug
AC Hotel by Marriott San Antonio Riverwalk

9. Element by Marriott San Antonio Riverwalk

Element by Marriott San Antonio Riverwalk
4.0 star property
Main - Military Plaza, 5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,309 reviews)
"Great stay !"
United States
Zully
The price is AED 465
AED 550 total
includes taxes & fees
24 Aug - 25 Aug
Element by Marriott San Antonio Riverwalk

10. Hampton Inn & Suites by Hilton San Antonio Riverwalk

Hampton Inn & Suites by Hilton San Antonio Riverwalk
2.5 star property
Main - Military Plaza, 5.9 km from Jefferson
8.8 out of 10, Excellent, (1,556 reviews)
"Pool could’ve been bigger but over all we had a great stay!"
United States
Anthony
The price is AED 419
AED 495 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites by Hilton San Antonio Riverwalk

11. Home2 Suites by Hilton San Antonio Riverwalk, TX

Home2 Suites by Hilton San Antonio Riverwalk, TX
3.0 star property
Main - Military Plaza, 5.9 km from Jefferson
9.0 out of 10, Wonderful, (1,570 reviews)
"The space of our room was great for our family and the variety in breakfast!"
United States
Maricarmen
The price is AED 434
AED 506 total
includes taxes & fees
30 Aug - 31 Aug
Home2 Suites by Hilton San Antonio Riverwalk, TX

12. Hotel Valencia Riverwalk

Hotel Valencia Riverwalk
4.5 star property
Downtown San Antonio, 5.9 km from Jefferson
9.4 out of 10, Exceptional, (3,034 reviews)
"Really enjoyed my stay!"
United States
Kenny
The price is AED 415
AED 596 total
includes taxes & fees
7 Sep - 8 Sep
Hotel Valencia Riverwalk

13. Holiday Inn Express & Suites San Antonio-Dtwn Market Area by IHG

Holiday Inn Express & Suites San Antonio-Dtwn Market Area by IHG
2.5 star property
6 km from Jefferson
8.0 out of 10, Very Good, (1,013 reviews)
"Staff is very friendly and courteous. Rooms are very clean."
United States
Olga L
The price is AED 257
AED 300 total
includes taxes & fees
14 Sep - 15 Sep
Holiday Inn Express & Suites San Antonio-Dtwn Market Area by IHG

14. Holiday Inn San Antonio - Riverwalk by IHG

Holiday Inn San Antonio - Riverwalk by IHG
3.0 star property
Downtown San Antonio, 5.9 km from Jefferson
8.4 out of 10, Very Good, (1,558 reviews)
"Best hotel"
United States
Irasema
The price is AED 397
AED 476 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn San Antonio - Riverwalk by IHG

15. Hampton Inn & Suites San Antonio-Downtown/Market Square

Hampton Inn & Suites San Antonio-Downtown/Market Square
2.5 star property
Downtown San Antonio, 6.1 km from Jefferson
9.0 out of 10, Wonderful, (1,345 reviews)
"Hotel & staff were amazing."
United States
ANITA
The price is AED 313
AED 382 total
includes taxes & fees
27 Aug - 28 Aug
Hampton Inn & Suites San Antonio-Downtown/Market Square

16. La Quinta Inn & Suites by Wyndham San Antonio Downtown

La Quinta Inn & Suites by Wyndham San Antonio Downtown
3.0 star property
Arsenal, 6.1 km from Jefferson
9.0 out of 10, Wonderful, (3,615 reviews)
"Great place to stay"
United States
Alyssa
The price is AED 320
AED 381 total
includes taxes & fees
30 Aug - 31 Aug
La Quinta Inn & Suites by Wyndham San Antonio Downtown

17. Canopy San Antonio Riverwalk

Canopy San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 6 km from Jefferson
9.4 out of 10, Exceptional, (1,708 reviews)
"The place was nice and clean!"
United States
Byron
The price is AED 605
AED 814 total
includes taxes & fees
23 Aug - 24 Aug
Canopy San Antonio Riverwalk

18. Best Western Alamo Suites

Best Western Alamo Suites
2.5 star property
6.2 km from Jefferson
8.6 out of 10, Excellent, (1,006 reviews)
"It was a very pleasant stay 5 min drive to the river walk."
United States
Miesha
The price is AED 279
AED 326 total
includes taxes & fees
20 Aug - 21 Aug
Best Western Alamo Suites

19. Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 6.1 km from Jefferson
9.4 out of 10, Exceptional, (5,124 reviews)
"Great Stay"
United States
Jesse
The price is AED 470
AED 556 total
includes taxes & fees
23 Aug - 24 Aug
Drury Plaza Hotel San Antonio Riverwalk

20. Riverwalk Plaza

Riverwalk Plaza
4.0 star property
Main - Military Plaza, 6.1 km from Jefferson
8.0 out of 10, Very Good, (6,484 reviews)
"Will definitely stay there again"
United States
Lauro
The price is AED 314
AED 371 total
includes taxes & fees
8 Sep - 9 Sep
Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Jefferson

Find the best Jefferson areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Uptown

While visiting Uptown, you might make a stop by sights like Alamo Quarry Market and San Antonio Zoo and Aquarium.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and Cinemark San Antonio 16.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Top Jefferson Hotel Reviews

Frequently asked questions

What is Jefferson like?
Travelers to San Antonio's Jefferson neighborhood will be sure to enjoy a stay in this neighborhood. Consider a visit to Woodlawn Lake Park as part of your Jefferson travel plans.
How many hotels will I be able to find in Jefferson?
Expedia has 43 hotels and other accommodations in Jefferson to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Jefferson, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review the best options available in Jefferson.
Where can I learn more about changing or cancelling my trip to Jefferson?
To access more information about picking new dates or cancelling your trip to Jefferson, click here.
What are the top things to see and do in Jefferson?
Woodlawn Lake Park is an attraction you might want to check out while you're in Jefferson. While you're out sightseeing in San Antonio, be sure to visit other sights like Woodlawn Theater or The Starlighter.