Hotels near San Diego Santa Fe Depot

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Feb - 10 Feb
Tomorrow
10 Feb - 11 Feb
This weekend
13 Feb - 15 Feb
Next weekend
20 Feb - 22 Feb

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego Santa Fe Depot hotels

Restaurant

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,004 reviews)
"Great Stay"
Canada
Carol
The price is AED 724
AED 841 total
includes taxes & fees
8 Mar - 9 Mar
Springhill Suites San Diego Downtown/Bayfront
Lobby sitting area

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,005 reviews)
"Great location and stay. "
United States
Simran
The price is AED 380
AED 547 total
includes taxes & fees
22 Feb - 23 Feb
Staypineapple, Hotel Z, Gaslamp San Diego
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,002 reviews)
"Great place to stay!"
Canada
Rose Marie JOy
The price is AED 654
AED 758 total
includes taxes & fees
22 Feb - 23 Feb
Marriott Vacation Club®, San Diego
Restaurant

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (652 reviews)
"Very nice hotel… Great little outdoor restaurant on the fifth floor"
United States
Kim
The price is AED 988
AED 1,147 total
includes taxes & fees
16 Feb - 17 Feb
Residence Inn by Marriott San Diego Downtown/Bayfront
Terrace/patio

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
0.1 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,117 reviews)
"The staff was awesome!! "
United States
Paolo
The price is AED 657
AED 762 total
includes taxes & fees
15 Feb - 16 Feb
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Lobby

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
0.4 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,011 reviews)
"Clean rooms, friendly staff, hotel close to eateries "
United States
Debbie
The price is AED 534
AED 618 total
includes taxes & fees
22 Feb - 23 Feb
Best Western Plus Bayside Inn
Reception

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (807 reviews)
"The room was clean!"
United States
Jiho
Stay Classy Hostel
Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 1.4 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (672 reviews)
"Great place to stay "
United States
KELLY
The price is AED 496
AED 682 total
includes taxes & fees
12 Feb - 13 Feb
Sentral Gaslamp Quarter
Front of property

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 0.8 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (668 reviews)
"excellent stay "
United States
Griselda
The price is AED 621
AED 720 total
includes taxes & fees
16 Feb - 17 Feb
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
0.9 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,033 reviews)
"Clean rooms and friendly staff"
United States
Topeka
The price is AED 426
AED 494 total
includes taxes & fees
22 Feb - 23 Feb
The DEXTRO Little Italy, BW Premier Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to San Diego Santa Fe Depot

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Restaurant
Springhill Suites San Diego Downtown/Bayfront
3.5 star property
9.2
Wonderful
1,004 reviews
View
Lobby sitting area
Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
9.4
Exceptional
1,005 reviews
View
Exterior
Marriott Vacation Club®, San Diego
3.5 star property
9.4
Exceptional
1,002 reviews
View
Restaurant
Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
9.2
Wonderful
652 reviews
View
Terrace/patio
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
9.0
Wonderful
1,117 reviews
View

Top San Diego Santa Fe Depot Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

10/10 Excellent
"Room did have a dirty carpet stain from previous people. Other than that service was great, great environment. Definitely will return in future. Beautiful aesthetic!!! "
Brianda 2-night trip
Posted 17 hours ago
Lafayette Hotel & Club

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 845 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, The Sofia Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good options close by include Manchester Grand Hyatt San Diego and Hard Rock Hotel San Diego.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 845 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Casa de Balboa are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.