Hotels near San Diego Santa Fe Depot

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
5 Feb - 6 Feb
Tomorrow
6 Feb - 7 Feb
This weekend
6 Feb - 8 Feb
Next weekend
13 Feb - 15 Feb

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego Santa Fe Depot hotels

Reception

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (805 reviews)
"The room was clean!"
United States
Jiho
Stay Classy Hostel
Restaurant

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,001 reviews)
"Great Stay"
Canada
Carol
The price is AED 724
AED 841 total
includes taxes & fees
8 Mar - 9 Mar
Springhill Suites San Diego Downtown/Bayfront
Lobby sitting area

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,001 reviews)
"Great location and stay. "
United States
Simran
The price is AED 380
AED 547 total
includes taxes & fees
22 Feb - 23 Feb
Staypineapple, Hotel Z, Gaslamp San Diego
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,000 reviews)
"Great place to stay!"
Canada
Rose Marie JOy
The price is AED 621
AED 720 total
includes taxes & fees
23 Feb - 24 Feb
Marriott Vacation Club®, San Diego
Restaurant

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (652 reviews)
"Very nice hotel… Great little outdoor restaurant on the fifth floor"
United States
Kim
The price is AED 939
AED 1,090 total
includes taxes & fees
22 Feb - 23 Feb
Residence Inn by Marriott San Diego Downtown/Bayfront
Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 1.4 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (664 reviews)
"Great place to stay "
United States
KELLY
The price is AED 434
AED 610 total
includes taxes & fees
12 Feb - 13 Feb
Sentral Gaslamp Quarter
Lobby

Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection
4.0 star property
0.3 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,212 reviews)
"The location is convenient and the hotel ambiance is great. Food and drinks in the hotel restaurant is also really good. "
Canada
Evelyn
The price is AED 477
AED 723 total
includes taxes & fees
15 Feb - 16 Feb
Hotel Republic San Diego, Autograph Collection
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (115 reviews)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Terrace/patio

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
0.1 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,114 reviews)
"The staff was awesome!! "
United States
Paolo
The price is AED 657
AED 762 total
includes taxes & fees
7 Feb - 8 Feb
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Interior

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 0.9 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (553 reviews)
"The staff was always so nice and friendly, breakfast options were just cereals. The room and bathrooms were always clean so 10/10 "
United States
Adriana
Gaslamp Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Diego Santa Fe Depot Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Room was very clean and luxurious "
lisa 1-night trip
Posted 1 day ago
Hard Rock Hotel San Diego

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 845 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, The Sofia Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good options close by include Manchester Grand Hyatt San Diego and Hard Rock Hotel San Diego.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 845 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Casa de Balboa are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.