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Find hotels in Santa Ana, Panama City from AED 202

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Discover 1,540 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Casco View Apartments
3.5 star property
9.2 out of 10, Wonderful, (50)
"Great stay, would recommend."
United States
Brooke
Casco View Apartments
Hotel República
2.0 star property
6.6 out of 10, (178)
"Fantastic customer service"
United States
OLGA
Hotel República
ART CASCO The Hotel
2.0 star property
6.4 out of 10, (9)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel
Hostal La Cigarra
2.5 star property
7.6 out of 10, Good, (54)
"Helpful staff, secure, close to sights"
Australia
Suzanne
Hostal La Cigarra
Hotel Riazor
3.0 star property
3.8 out of 10, (11)
"Rough neighborhood "
Canada
Del
Hotel Riazor
La Manzana by Wynwood House
3.0 star property
7.2 out of 10, Good, (15)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is AED 195
AED 288 total
includes taxes & fees
23 Nov - 24 Nov
La Manzana by Wynwood House
Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is AED 537
AED 591 total
includes taxes & fees
11 Nov - 12 Nov
Room-sofa Bed Stay Rooftop Pool & Gym, A
Crowne Plaza Panama Airport by IHG
4.0 star property
8.4 out of 10, Very Good, (2278)
"Good place right next to the airport"
United States
alejandro
The price is AED 444
AED 489 total
includes taxes & fees
2 Nov - 3 Nov
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo
4.0 star property
9.2 out of 10, Wonderful, (1000)
"Very beautiful hotel with helpful staff. Very good dining options. "
United States
Joseph
The price is AED 1,052
AED 1,157 total
includes taxes & fees
28 Nov - 29 Nov
Central Hotel Panama Casco Viejo
La Concordia Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (189)
"Clean, safety, nice staff, decoration and quite building "
United States
Claudia
The price is AED 805
AED 886 total
includes taxes & fees
16 Nov - 17 Nov
La Concordia Boutique Hotel
Hotel Coral Suites
3.5 star property
9.0 out of 10, Wonderful, (1005)
"This place is nice for a overnight stay"
United States
Gwendolyn
The price is AED 255
AED 280 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Coral Suites
TRYP by Wyndham Panamá Centro
3.5 star property
9.2 out of 10, Wonderful, (1007)
"Great affordable dining and service "
United States
Sean
The price is AED 329
AED 362 total
includes taxes & fees
31 Oct - 1 Nov
TRYP by Wyndham Panamá Centro
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (4446)
"Great stay, clean, great restaurants, nearby for business travels"
United States
Christian
The price is AED 420
AED 462 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Riu Plaza Panama
Principe Hotel and Suites
3.0 star property
9.0 out of 10, Wonderful, (1554)
"A nice hotel with plenty of shopping and restaurants in the area"
United States
Neil
The price is AED 184
AED 202 total
includes taxes & fees
1 Nov - 2 Nov
Principe Hotel and Suites
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (652)
"Yes Ac work well and everything works out well Place is lovely and great service "
United States
Sandy
The price is AED 198
AED 218 total
includes taxes & fees
2 Nov - 3 Nov
Hospedium Princess Hotel Panama
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very Good, (1160)
"Great stay "
United States
Mark
The price is AED 474
AED 521 total
includes taxes & fees
21 Nov - 22 Nov
Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2124)
"great property and staff "
United States
Yunior
The price is AED 581
AED 639 total
includes taxes & fees
5 Nov - 6 Nov
Plaza Paitilla Inn Hotel
Novotel Panama City
4.0 star property
9.2 out of 10, Wonderful, (1046)
"Friendly staff and a great variety in the buffet."
United States
Zoraida
The price is AED 360
AED 396 total
includes taxes & fees
2 Nov - 3 Nov
Novotel Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (621)
"The staff were fantastic. The service was great. "
United States
SANDRO
The price is AED 756
AED 832 total
includes taxes & fees
23 Nov - 24 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Riande Aeropuerto Hotel & Casino
4.0 star property
8.6 out of 10, Excellent, (1889)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is AED 632
AED 695 total
includes taxes & fees
31 Oct - 1 Nov
Riande Aeropuerto Hotel & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Ana with free breakfast

Hotels in Santa Ana with a pool

Top guest rated hotels in Santa Ana

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Vibrant Nightlife: Experience the lively bar scene in Santa Ana, perfect for those looking to enjoy Panama City's nightlife.
  • Cultural Attractions: Visit historical sites such as Santa Ana Casco Viejo and local museums to immerse yourself in Panama's rich heritage.
  • Stunning Views: Enjoy picturesque hilltop views that provide a breathtaking backdrop for your vacation.
  • Family-Friendly Activities: Explore various attractions and parks that cater to visitors of all ages.
  • Diverse Accommodations: Choose from a range of hotels and apartments that meet different needs and preferences.

Find great hotels near Santa Ana

Santa Ana offers a diverse selection of accommodations, including hotels and apartments, perfect for every traveler. Whether you seek a pet-friendly stay, a business-friendly environment, or a relaxed vacation experience, you'll find suitable options. With popular choices like Hotel El Panama and various city-themed hotels, Santa Ana is an ideal base for exploring Panama City while enjoying modern amenities and a welcoming atmosphere.

  • Central Hotel Panama Casco Viejo: Experience romance and luxury at the Central Hotel Panama Casco Viejo, a 4-star gem located a mere 805m from Santa Ana. This hotel is an ideal choice for couples seeking a romantic getaway, featuring enticing romance packages and exquisite food and beverage services, including 24-hour room service and champagne service. Guests can indulge in rejuvenating spa treatments, with amenities like facial treatments and a full-service spa available. The hotel’s central location makes it a perfect base for exploring the vibrant city while enjoying a serene retreat.
  • American Trade Hotel: The American Trade Hotel, a stylish 4.5-star property located 644m from Santa Ana, caters to business travelers and pet owners alike. This city-themed hotel provides a blend of comfort and convenience, allowing some pets on-site with waived fees for service animals. Guests can enjoy modern amenities and a prime location in the heart of the city, making it easy to conduct business or explore nearby attractions. With its elegant design and thoughtful services, the American Trade Hotel is perfect for those combining work and leisure.
  • Innfiniti Hotel & Suites: Offering a welcoming atmosphere, the Innfiniti Hotel & Suites is a 3.5-star accommodation located 1.4km from Santa Ana. This city-themed hotel is tailored for business travelers, providing essential amenities and a convenient location in the bustling city center. With comfortable rooms and a focus on guest satisfaction, Innfiniti is an excellent choice for those looking to balance work and relaxation during their stay in Panama City.

Where to stay near Santa Ana

Santa Ana, a vibrant neighborhood in Panama City, offers a unique blend of family-friendly attractions and business opportunities. Visitors can enjoy the welcoming atmosphere and explore nearby areas that showcase the rich culture of Panama. From local markets to luxurious accommodations, Santa Ana caters to all types of travelers seeking relaxation or adventure. Immerse yourself in the charm of this lively neighborhood while discovering the diverse experiences that Panama City has to offer.

  • Panama City: The vibrant heart of Panama, Panama City boasts a unique blend of modern skyscrapers and historic neighborhoods. Santa Ana is situated within its bustling limits, making it a convenient base for your adventures. Travelers flock here year-round, with peak visits in January, July, and September, drawn by its family-friendly atmosphere and urban experiences. Don't miss the chance to explore shopping centers and malls, while local attractions like beaches, parks, and lively streets offer a perfect backdrop for relaxation and exploration.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a historic neighborhood filled with charming cobblestone streets and colonial architecture. This area is particularly popular in January and the spring months, catering to families and outdoor enthusiasts alike. Visitors can indulge in shopping at local markets and enjoy the vibrant atmosphere of cafes and restaurants. With close proximity to beautiful parks and stunning beachfront views, Casco Viejo is a must-visit for those looking to soak in the culture and history of Panama City.
  • San Felipe: Also located 644m from Santa Ana, San Felipe is known for its rich history and cultural landmarks. This neighborhood attracts families and outdoor lovers, especially during peak seasons in February, March, and December. Explore local resorts and shopping areas, and take a leisurely stroll through picturesque parks or along the beach. With historic sites nearby, San Felipe offers a delightful mix of recreation and education, making it an enriching stop on your Panama journey.

Things to do near Santa Ana

Santa Ana offers a vibrant mix of family-friendly and business-themed activities perfect for any traveler. Explore nearby shopping malls and centers, or indulge in the local bar crawl to experience Panama City's lively nightlife. Whether you're looking to shop or enjoy entertainment, Santa Ana provides a variety of options to make your vacation enjoyable and memorable.

Shopping

For a great shopping experience in Santa Ana, visit Albrook Shopping Mall, just 1.6km away, offering a mix of entertainment and family vibes. Avenida Central, only 483m away, features a lively atmosphere, while Uruguay Street, 3.2km away, is perfect for exploring local shops.

Recreation

In Santa Ana, you can visit Maracana Stadium for an energetic atmosphere, perfect for sports enthusiasts. Estadio Rommel Fernandez and Estadio Nacional Rod Carew offer vibrant sports experiences, making them excellent spots to enjoy local games and immerse yourself in Panama's sports culture.

Adventure

Explore the Honeycreeper Ridge Trail, a stunning hiking trail 43.5km from Santa Ana, offering breathtaking scenery and a chance to connect with nature. For an adrenaline rush, visit Gatun Eco Adventures, a thrilling zipline ropes course located 48.3km away, perfect for adventure seekers.

Nightlife

In Santa Ana, the vibrant nightlife features venues like the National Theater, Anita Villalaz Theater, and Amador Theater, all within 1.6km's reach. Each offers a unique blend of romance, culture, and entertainment, making for an enchanting evening in Panama City.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

To save money on your trip to Santa Ana, consider visiting between September and November, when prices are lower. Book your stay on a Tuesday for the best rates, as Saturdays tend to be the most expensive. Use Expedia’s search tool to filter options by budget and location, and arrange results from lowest to highest price. Additionally, combining hotel reservations with flights and activities through an Expedia package deal can lead to significant savings. Don't forget to look for expedia coupons to maximize your budget.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana offers a delightful mix of family-friendly, city-themed, and business vacation options. Visitors can explore fascinating attractions like hilltop views, history museums, and cathedrals. Key points of interest include Santa Ana Casco Viejo, Plaza Santa Ana, Panama City Beach, Santa Ana Square, and Playa Bonita. These sites provide a rich cultural experience, stunning scenery, and a taste of local history, ensuring a memorable visit for travelers.

  • Metropolitan Cathedral of Panama: An architectural marvel, this cathedral features stunning colonial design and intricate details. Visitors can immerse themselves in the rich history and vibrant cultural atmosphere that surrounds this sacred space.
  • Interoceanic Canal Museum: Delve into the fascinating history of the Panama Canal at this engaging museum. With interactive exhibits and informative displays, you'll gain insights into the canal's significance and impact on global trade and travel.
  • Ancon Hill: Offering breathtaking panoramic views of Panama City and the canal, Ancon Hill is perfect for outdoor enthusiasts. Enjoy a scenic hike or leisurely stroll amidst lush greenery and diverse wildlife, making it a peaceful retreat from urban life.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Traveling to Santa Ana, Panama is convenient with access to major airports. Panama City (PTY-Tocumen Intl.) is located 20.9km away, with nearby hotels like The Santa Maria, a Luxury Collection Hotel, 8.0km from the airport, and JW Marriott Panama, 16.1km away. Alternatively, Panama City (PAC-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as Waldorf Astoria Panama and Sofitel Legend Casco Viejo, both within 3.2km of the airport. For a more remote option, Rio Hato (RIH-Scarlett Martinez Intl.) is 91.7km away, with resorts like The Buenaventura Golf & Beach Resort offering transport services to the airport.

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Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 110 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.