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Go beyond your typical stay in Santa Cruz

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Check prices for these dates

Tonight
13 Nov - 14 Nov
Tomorrow
14 Nov - 15 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Santa Cruz hotels

A hotel sign with a sun emblem, a modern glass building, and flags.

1. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
9.0 out of 10, Wonderful, (1,002 reviews)
"Location, service is wonderful"
United States
Rene
The price is AED 234
AED 234 total
14 Dec - 15 Dec
La Quinta by Wyndham Medellin
A modern hotel room with a large bed, bedside table with a lamp, a desk with a chair, and a potted plant.

2. Moa Select

Moa Select
3.0 star property
Laureles
9.4 out of 10, Exceptional, (449 reviews)
"I stay here ones a month and it’s always a great experience. Great staff and clean bedrooms. Also very convenient location close to malls and restaurants"
United States
Jose
The price is AED 178
AED 178 total
14 Dec - 15 Dec
Moa Select
A buffet with various fruits, vegetables, and beverages.

3. ibis Medellin

ibis Medellin
3.0 star property
El Poblado
8.8 out of 10, Excellent, (1,000 reviews)
"Everything was great about this hotel. The staff super friendly and helpful. Clean and room cleaning was excellent. The breakfast buffet was out this world!!! While it not the most fancy of hotels it is very comfortable. Cant beat the price and location!"
United States
Martha Lucia
The price is AED 176
AED 176 total
6 Dec - 7 Dec
ibis Medellin
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.

4. Hotel Dorado La 70

Hotel Dorado La 70
4.0 star property
Laureles
9.0 out of 10, Wonderful, (1,916 reviews)
"Very good place to stay."
United States
Gregson
The price is AED 251
AED 251 total
24 Nov - 25 Nov
Hotel Dorado La 70
A modern interior with a wooden ceiling, a reception desk, and a display of baked goods.

5. Eutopiq Hotel

Eutopiq Hotel
3.5 star property
Laureles
9.4 out of 10, Exceptional, (365 reviews)
"Breakfasts, clean room, excellent customer service"
United States
Ramiro
The price is AED 234
AED 234 total
14 Dec - 15 Dec
Eutopiq Hotel
A modern bar with a long counter, shelves with decorative items, and a coffee machine.

6. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,484 reviews)
"Great stay!"
United States
Haydee
The price is AED 461
AED 461 total
27 Nov - 28 Nov
Novotel Medellín El Tesoro
A hotel lobby with a reception desk, seating area, and a large chandelier.

7. Hotel Egina Medellín

Hotel Egina Medellín
3.0 star property
Laureles - Estadio
8.4 out of 10, Very good, (1,000 reviews)
"Great service, friendly people"
United States
David
The price is AED 219
AED 219 total
14 Dec - 15 Dec
Hotel Egina Medellín
A pathway leading to a building with a modern design, surrounded by lush greenery and trees.

8. Hotel centro logistico del norte

Hotel centro logistico del norte
2.0 star property
Bello
10.0 out of 10, Exceptional, (4 reviews)
"Excelente muy buena atención"
United States
Sergio
The price is AED 54
AED 100 total
18 Nov - 19 Nov
Hotel centro logistico del norte
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and a brick building.

9. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
El Poblado
8.8 out of 10, Excellent, (1,008 reviews)
"Very nice hotel !!!"
United States
jaime
The price is AED 305
AED 305 total
15 Nov - 16 Nov
Hotel Dann Carlton Belfort Medellin
A rooftop bar with tables and chairs, a bar counter, and a city view at night.

10. Indie Universe Creative Hotel

Indie Universe Creative Hotel
4.5 star property
Laureles
8.6 out of 10, Excellent, (225 reviews)
"Great place to stay"
United States
Sypoutha Michael
The price is AED 160
AED 160 total
16 Nov - 17 Nov
Indie Universe Creative Hotel
A restaurant with wooden tables and benches, a bar area, and large windows offering a view of greenery.

11. V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
3.5 star property
El Poblado
9.2 out of 10, Wonderful, (1,355 reviews)
"I love this place, great breakfast and beautiful views from the rooms."
United States
James
The price is AED 347
AED 347 total
27 Nov - 28 Nov
V Grand Hotel, a member of Radisson Individuals
A modern interior with a circular window, a seating area with a cushioned bench, and a small table.

12. Garden Hotel by Urbit

Garden Hotel by Urbit
3.0 star property
Laureles
9.2 out of 10, Wonderful, (109 reviews)
"Great place to stay!"
United States
Elio Rafael
The price is AED 187
AED 187 total
15 Nov - 16 Nov
Garden Hotel by Urbit
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.

13. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (291 reviews)
"It was a really good stay. Thought it was inconvenient not to be able to charge expenses to the room like in most hotels, but it was nice regardless. The staff in general were very nice, Oscar especially was very attentive and helpful."
United States
Estefania
The price is AED 316
AED 316 total
11 Dec - 12 Dec
Fairfield by Marriott Medellin Sabaneta
A hotel room with a bed, a glass-enclosed bathtub, a small table with a chair, and a window with a view of buildings.

14. Arame Hotel

Arame Hotel
3.0 star property
Envigado
9.2 out of 10, Wonderful, (231 reviews)
"I would stay there again without a doubt"
United States
David
The price is AED 294
AED 294 total
16 Nov - 17 Nov
Arame Hotel
A modern bathroom with a hot tub, large windows, and a view of greenery.

15. Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
3.0 star property
Laureles
9.6 out of 10, Exceptional, (192 reviews)
"I have stayed several times and enjoyed each stay. The hotel is conveniently located in a nice neighborhood"
United States
Richard
The price is AED 154
AED 154 total
14 Dec - 15 Dec
Hotel Ryo 74B Suites by Growing Group
A bedroom with a large bed, a chair, and a view through a glass door.

16. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.4 out of 10, Exceptional, (788 reviews)
"GREAT LOCATION"
United States
Emilia
The price is AED 289
AED 289 total
27 Nov - 28 Nov
Isak Hotel & Golf Airport
A modern kitchen with a central island, a buffet setup, and a view of the city through large windows.

17. Hotel BH El Poblado

Hotel BH El Poblado
3.5 star property
El Poblado
9.2 out of 10, Wonderful, (1,001 reviews)
"Great Hotel"
United States
Francisco
The price is AED 216
AED 216 total
14 Dec - 15 Dec
Hotel BH El Poblado
A reception desk with a computer, potted plants, and a television screen.

18. Hotel Sauces Del Estadio

Hotel Sauces Del Estadio
3.0 star property
Laureles - Estadio
8.4 out of 10, Very good, (197 reviews)
"Absolutely love this hotel, incredible staff "
United States
luz
The price is AED 160
AED 160 total
16 Nov - 17 Nov
Hotel Sauces Del Estadio
A modern kitchen with a central island, bar area, and seating.

19. Loma, Medellin, a Tribute Portfolio Hotel

Loma, Medellin, a Tribute Portfolio Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (468 reviews)
"Such a gem of a hotel reasonably priced food in the restaurant which was delicious. Free breakfast had many options. The gym was functional and decently equipped. The most important the place was spotless and the staff is A1"
United States
Ace Amari
The price is AED 367
AED 367 total
20 Nov - 21 Nov
Loma, Medellin, a Tribute Portfolio Hotel
A modern hotel room with a large bed, a separate bathroom with a bathtub, and a large window offering a city view.

20. Hotel Lincoln

Hotel Lincoln
3.5 star property
Laureles
8.6 out of 10, Excellent, (564 reviews)
"Very guest service, and the rooms are very clean"
United States
Leonardo
The price is AED 203
AED 203 total
15 Nov - 16 Nov
Hotel Lincoln
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

A modern bedroom with a large bed, a small table, and a chair.
Firenze Lofts

Firenze Lofts

Firenze Lofts
La América

10/10 Excellent

The rooms were very accommodating and clean with a very comfortable bed and usable kitchenette.
United States
Alan
Reviewed April 9, 2025
Firenze Lofts

Frequently Asked Questions

What's the top vacation rental that Santa Cruz has to offer?

6 Bedrooms House near Tourist Spots with backyard, Bar, Jacuzzi and heated pool: This vacation home rental near Santa Cruz offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You can relax into your vacation with a garden and a hot tub. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

For additional details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What is staying in Santa Cruz like?

Visitors are sure to enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 4 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What are the top places to visit in Santa Cruz?

Places to visit in the wider area include Medellin Botanical Garden, Arvi Park, and Antioquia Museum. You'll also find Botero Plaza and Atanasio Giradot Stadium in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

How can I get around Santa Cruz?

Head over to Andalucía MetroCable Station for metro transit.

What's the weather like in Santa Cruz?

The hottest months are usually August and July with an average temp of 66°F, while the coldest months are December and January with an average of 64°F. The rainiest months in Santa Cruz are May, April, October, and November, with each month seeing an average of 16 inches of rainfall.

Where is the best place to stay in Santa Cruz?

Located 6.2 mi (10 km) from the heart of Santa Cruz, Calle Flora Hotel by Jalo is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in Santa Cruz.