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Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov
In one month
4 Dec - 6 Dec
In two months
1 Jan - 3 Jan
No exact matches found, but these alternatives could be just right

Recommended hotels in Santa Cruz

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

1. Lido Hotel

Lido Hotel
3.0 star property
Centro Histórico
9.2 out of 10, Wonderful, (57 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is AED 86
AED 86 total
14 Nov - 15 Nov
Lido Hotel
A modern hotel lobby with a reception desk, seating area, and a large glass wall with a sign.

2. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Equipetrol
9.4 out of 10, Exceptional, (159 reviews)
"Good location and value for money."
United States
Hui Hua
The price is AED 131
AED 131 total
25 Nov - 26 Nov
Ibis Santa Cruz DE LA Sierra
A multi-level indoor space with a pool, wooden flooring, and potted plants.

3. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Centro Histórico
9.2 out of 10, Wonderful, (140 reviews)
"Small but beautiful and very much in the center"
United States
Rajendra
The price is AED 196
AED 196 total
29 Nov - 30 Nov
Cosmopolitano Hotel Boutique
A swimming pool with a decorative center, surrounded by a building with a blue roof and a mural.

4. Gran Hotel Santa Cruz

Gran Hotel Santa Cruz
4.5 star property
Centro Histórico
The price is AED 205
AED 205 total
10 Nov - 11 Nov
Gran Hotel Santa Cruz
A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

5. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (418 reviews)
"The room and the bed, towels were very clean.The breakfast was very complete and very good."
Canada
Andre Leo
The price is AED 387
AED 387 total
9 Nov - 10 Nov
Sun Hotel
A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

6. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (261 reviews)
"Amazing hotel"
United States
Deivis
The price is AED 453
AED 453 total
14 Nov - 15 Nov
Marriott Santa Cruz de la Sierra Hotel
A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (292 reviews)
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
United States
Scott
The price is AED 270
AED 270 total
13 Nov - 14 Nov
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
A hotel room with a bed, a desk, a chair, a large window, and a plant.

8. 518 RENT

518 RENT
3.0 star property
Centro Histórico
The price is AED 41
AED 60 total
9 Nov - 10 Nov
518 RENT
A poolside area with lounge chairs and a palm tree.

9. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (426 reviews)
"I love how nice and helpful staff was."
United States
Lizzie
The price is AED 559
AED 559 total
14 Nov - 15 Nov
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

10. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (61 reviews)
"Clean room, good staff,"
United States
Neftali
The price is AED 161
AED 161 total
9 Nov - 10 Nov
HOTEL OSHO
A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

11. Hotel Las Américas

Hotel Las Américas
3.0 star property
Centro Histórico
8.0 out of 10, Very good, (35 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is AED 89
AED 89 total
9 Nov - 10 Nov
Hotel Las Américas
The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

12. Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (81 reviews)
"clean close to restaurants friendly staff shop nearby overall excellent place to stay"
United States
Luis
The price is AED 174
AED 174 total
14 Nov - 15 Nov
Chairú Eco Hotel
A modern bedroom with a bed, bedside table, and a desk with a laptop.

13. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (112 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is AED 83
AED 83 total
7 Dec - 8 Dec
Hotel G
A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

14. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
The price is AED 154
AED 154 total
10 Nov - 11 Nov
Premium Suites Deluxe Aparthotel Equipetrol
Breakfast area

15. Gran Hotel Mediterráneo

Gran Hotel Mediterráneo
3.5 star property
Centro Histórico
10.0 out of 10, Exceptional, (1 review)
"Desde a recepção, a equipe da limpeza e o pessoal do café da manhã, foram sempre muito prestativos e disponíveis para ajudar no que foi necessário, voltaremos. A localização é bem próxima a praça central."
Brazil
Emerson
The price is AED 201
AED 201 total
9 Nov - 10 Nov
Gran Hotel Mediterráneo
A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

16. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
The price is AED 86
AED 86 total
10 Nov - 11 Nov
Apart Hotel Premium Suites Santa Cruz
A rooftop pool with clear skies and a city view.

17. Hotel Pascana centro

Hotel Pascana centro
3.5 star property
Centro Histórico
9.4 out of 10, Exceptional, (3 reviews)
"El hotel se encuentra en el Centro histórico de la ciudad, es una estructura dentro del marco historico de la ciudad, pero se encuentra en buenas condiciones. Con facil acceso al transporte. Camina el centro de la ciudad histórica con tranquilidad."
United States
Miguel
The price is AED 239
AED 239 total
17 Nov - 18 Nov
Hotel Pascana centro
A hotel room with a large bed, a bedside table, a lamp, and artwork on the walls.

18. Sarao

Sarao
3.0 star property
Centro Histórico
The price is AED 83
AED 101 total
9 Nov - 10 Nov
Sarao
A resort with a large swimming pool, lounge chairs, and a building labeled 'MARA GRANDE Country Club'.

19. Mora Grande

Mora Grande
3.0 star property
Santa Cruz
The price is AED 204
AED 204 total
10 Nov - 11 Nov
Mora Grande
A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

20. Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (456 reviews)
"The food is excellent quality and delicious! Friendly staff"
United States
Wendy
The price is AED 450
AED 450 total
6 Dec - 7 Dec
Camino Real Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Top reviews in Santa Cruz

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.
Chairú Eco Hotel

Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz

10/10 Excellent

Nice and clean
United States
Brian
Reviewed October 28, 2026
Chairú Eco Hotel

Frequently Asked Questions

What can I expect from a motel trip to Santa Cruz?

If you're having trouble locating a motel in Santa Cruz, expand your search to find motels in the surrounding area or let us help you find a similar property from over 312 hotels and other lodging options. Simply use our search tools to filter by nightly room rate or cost-effective amenities such as free parking and free airport transportation.

What are motels like?

Motels often offer free parking, and many also include an outdoor pool. Often one or two stories tall, motel properties usually have outdoor access to guestrooms from the parking lot. Introduced in the early 1950s, customized neon signs often lit up the roadside motels, and you can see these today along the historic U.S. Route 66.

What are the best motels in Santa Cruz?

Here are some budget-friendly accommodations to book in Santa Cruz. Ibis Santa Cruz DE LA Sierra - Hotel Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel - Hotel Marriott Santa Cruz de la Sierra Hotel - Guesthouse Novotel Santa Cruz De La Sierra - Hotel Sun Hotel - Hotel

What things can I to do in Santa Cruz?

Visitors like Santa Cruz for its shops. As you're sightseeing around the area, be sure to enjoy all there is to see and do. These are some of the parks and outdoorsy places: Arenal Park, Guembe Biocenter, and Lomas de Arena Regional Park. Attractions the whole family can enjoy include Santa Cruz Zoo and Play Land Amusement Park. During your trip, here are some other places to visit: Plaza 24 de Septiembre, Blacutt Square, and Ramon Tahuichi Aguilera Stadium.

What's the weather like in Santa Cruz?

Weather can make or break a roadtrip, so here's some data about year-round temperatures in Santa Cruz to help you plan yours: The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

What are my options for getting around Santa Cruz when staying in a motel?

We’ve gathered some information about local transportation options in Santa Cruz to help you navigate your stay: Fly into Santa Cruz (SRZ-El Trompillo), which is located 1.2 mi (1.9 km) away from the heart of the city. You can also search for flights into Santa Cruz (VVI-Viru Viru Intl.), which is 9.8 mi (15.8 km) away. To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station.