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Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov
In one month
4 Dec - 6 Dec
In two months
1 Jan - 3 Jan

Our top choices for Santa Isabel apartments

A swimming pool with lounge chairs and a covered area, surrounded by buildings.

1. Cozy 1-bedroom apartment in nice Mexicali/Campestre

Cozy 1-bedroom apartment in nice Mexicali/Campestre
Mexicali
The price is AED 184
AED 266 total
includes taxes & fees
7 Nov - 8 Nov
Cozy 1-bedroom apartment in nice Mexicali/Campestre
A hallway with a patterned floor, a sofa, and a wall with vertical wooden slats and greenery.

2. Downtown Apartment | 4 Guests

Downtown Apartment | 4 Guests
Mexicali
The price is AED 397
AED 524 total
includes taxes & fees
7 Nov - 8 Nov
Downtown Apartment | 4 Guests
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top reviews in Santa Isabel

A modern kitchen with a large island, bar stools, pendant lighting, and a staircase leading to an upper level.
Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali
Mexicali

10/10 Excellent

From the moment we checked in, I was amazed at the incredible staff, they were friendly, knowledgeable, and friendly. The complimentary breakfast was delicious, with anything you would want.
United States
Gabriel
Reviewed September 13, 2025
Fairfield Inn & Suites by Marriott Mexicali

Frequently Asked Questions

What's it like to stay at an apartment in Santa Isabel?

There are plenty of places to stay with in Mexicali, with 73 accommodation choices including 18 apartments.

How do you know if an apartment is a good option for you?

An apartment features a kitchen for convenient meals, and is often more spacious than a traditional hotel room. Apartments are a good option for couples looking to stay away from the tourist areas, but also for families wanting the conveniences of home.

What's a favorite apartment for my stay in Santa Isabel?

Below is a popular apartment in the area to consider: Casa Movil tipo estudio: Located 11.9 mi/19.2 km away in Mexicali. Amenities include free WiFi. Access to free parking is available on site.

What can I expect from the weather when I travel to Santa Isabel?

Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Santa Isabel. The hottest months are usually July and August with an average temp of 93°F, while the coldest months are December and January with an average of 61°F. Average annual precipitation for Santa Isabel is 3 inches.

What should I see and do in Santa Isabel?

Explore the area and family-friendly sights such as City Forest and Zoo, or get out into nature at a spot like Vicente Guerrero Park. In the larger area, you’ll find Mexicali Border Port I and Plaza Comercial La Cachanilla.

What's the best way to get to and around Santa Isabel?

Knowing a bit about the transportation options can save you time when you get to your destination. Fly into El Centro, CA (IPL-Imperial County), which is located 14.1 mi (22.7 km) from the heart of the city. You can also search for flights into Mexicali, Baja California Norte (MXL-General Rodolfo Sanchez Taboada Intl.), which is 18.7 mi (30.2 km) away. If you'd like to explore around the area, you may want a rental car for your journey.