Find Family Hotels in Santee, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santee Family Hotels

Top Santee Family Hotels

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
  • Cribs/infant beds
  • Outdoor pool
9.8 out of 10, Exceptional, (1002)
Family adventures thrive at this hotel, featuring a sparkling outdoor pool, premium TV channels, and movie options for kids. Located a 2-minute drive from Santee State Park, families enjoy free breakfast daily while appreciating the convenient firepit for evening gatherings.
The price is AED 426
AED 473 total
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Santee
Lobby
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 star property
Santee
  • Cribs/infant beds provided
8.0 out of 10, Very Good, (1001)
Sparkling clean accommodations await families at this recently remodeled hotel steps from Santee State Park. Children splash in the seasonal outdoor pool while parents appreciate the fitness center, free breakfast buffet, and helpful staff that consistently receives praise from travelers.
The price is AED 393
AED 436 total
includes taxes & fees
4 Dec - 5 Dec
Comfort Inn & Suites Santee
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 star property
Santee
  • Outdoor pool
8.8 out of 10, Excellent, (1000)
Splash into the outdoor pool or explore Santee State Park just a 2-minute drive away. Premium TV channels keep kids entertained while parents appreciate the comfortable beds, free breakfast, and convenient parking options.
The price is AED 434
AED 482 total
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Santee Inn
Exterior
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2.0 star property
Santee
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
7.0 out of 10, Good, (666)
The price is AED 224
AED 249 total
includes taxes & fees
4 Dec - 5 Dec
Travelodge by Wyndham Santee
Smart TV, offices
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee
  • Kitchen
  • Washer
  • Dryer
  • Pet friendly
  • Free WiFi
  • Air conditioning
10.0 out of 10, Exceptional, (36)
The price is AED 370
AED 1,210 total
includes taxes & fees
23 Nov - 24 Nov
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Exterior
Econo Lodge

Econo Lodge

2.0 star property
Santee
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • 24/7 front desk
  • Microwave
6.4 out of 10, (309)
The price is AED 231
AED 256 total
includes taxes & fees
7 Dec - 8 Dec
Econo Lodge
Desk, iron/ironing board, free cribs/infant beds, free WiFi
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

2.5 star property
Orangeburg
  • Cribs/infant beds provided
  • Indoor pool
8.0 out of 10, Very Good, (536)
Families delight in this Orangeburg retreat's indoor swimming pool where kids can play while parents use the fitness center. Spacious, comfortable rooms accommodate cribs, and the friendly staff ensures a welcoming environment, all with convenient access to the nearby planetarium.
The price is AED 350
AED 388 total
includes taxes & fees
23 Nov - 24 Nov
Comfort Inn & Suites Orangeburg
Exterior
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

2.5 star property
Orangeburg
  • Cribs/infant beds provided
8.6 out of 10, Excellent, (790)
Seasonal outdoor pool invites kids to splash and play while parents workout at the 24-hour fitness center. Spacious, quiet rooms feature premium TV channels and free cribs. Just 8 minutes from I.P. Stanback Museum & Planetarium for educational family fun.
The price is AED 448
AED 497 total
includes taxes & fees
24 Nov - 25 Nov
Holiday Inn Express & Suites Orangeburg by IHG
Free daily continental breakfast
Days Inn by Wyndham St George

Days Inn by Wyndham St George

2.5 star property
St. George
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
7.6 out of 10, Good, (1003)
The price is AED 275
AED 306 total
includes taxes & fees
23 Nov - 24 Nov
Days Inn by Wyndham St George
Front of property
Peach Tree Inn

Peach Tree Inn

2.5 star property
St. George
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Housekeeping
7.4 out of 10, Good, (129)
Peach Tree Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Friendly staff room was clean"
Lisa 2-night trip
Posted 4 days ago
Comfort Inn & Suites Santee

Explore a world of travel with Expedia

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you might want to check out some kid-friendly attractions such as Santee Indian Mound and Fort Watson Site and Orangeburg County Library Mentor Branch. Make sure you have lots of time for activities like Lake Marion and Taw Caw Creek.