An aerial view of a coastal landscape with a dam, farmland, and dense forests.

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Check availability on Santee Family Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Santee family-friendly hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,004 reviews)
"Convenient location close to the highway and restaurants. Large parking , excellent breakfast and comfortable room."
United States
Victor
The price is AED 509
AED 565 total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
"Nice place to stay"
United States
sandra
The price is AED 453
AED 503 total
includes taxes & fees
25 Nov - 26 Nov
Hampton Inn Santee-I-95
A modern lounge area with a mural, pool table, comfortable seating, and a large TV screen.

3. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (1,010 reviews)
"Nice little hotel conveniently located."
United States
Armando
The price is AED 372
AED 412 total
includes taxes & fees
22 Nov - 23 Nov
Tru By Hilton Santee
A hotel entrance with a sign reading "Best Western PLISS."

4. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,003 reviews)
"Nice location and very convenient parking, Breakfast was very good."
United States
Johnny
The price is AED 437
AED 485 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Plus Santee Inn
A hotel room with a bed, bedside table, lamp, and a mirror.

5. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,507 reviews)
"Good one night stay Staff was wonderful"
United States
Thomas
The price is AED 294
AED 326 total
includes taxes & fees
5 Nov - 6 Nov
Baymont by Wyndham Santee
A water park with a pool, slides, and umbrellas.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"Great staff and really clean room!"
United States
Traci
The price is AED 404
AED 448 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Santee by IHG
A swimming pool with a 5 ft depth marker, surrounded by lounge chairs and a building with multiple windows.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,006 reviews)
"Great hotel"
United States
Alexis
The price is AED 365
AED 405 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn & Suites Santee
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (787 reviews)
"Extremely good value for money, room was clean, tidy and very well appointed. Will absolutely come here again."
United States
Robert
The price is AED 235
AED 261 total
includes taxes & fees
5 Nov - 6 Nov
Travelodge by Wyndham Santee
A modern bathroom with a sink, toilet, and shower area.

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (477 reviews)
"An older fecility but certainly well maintained. Loved Mr. Patel!"
United States
William
The price is AED 234
AED 260 total
includes taxes & fees
10 Nov - 11 Nov
Super 8 by Wyndham Santee/I-95
A cabin with a porch, surrounded by trees and a body of water.

10. Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (668 reviews)
"Everything was adequate or good."
United States
Sharyn
The price is AED 231
AED 257 total
includes taxes & fees
8 Nov - 9 Nov
Red Roof Inn Santee
A hotel room with two beds, a desk, a chair, and a view of the hallway.

11. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (597 reviews)
"The price rate was great"
United States
Stevenson
The price is AED 282
AED 313 total
includes taxes & fees
30 Nov - 1 Dec
Ramada by Wyndham Santee I-95
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

12. Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (317 reviews)
"Pretty nice and clean with a comfortable bed at a great rate."
United States
Arthur
The price is AED 250
AED 277 total
includes taxes & fees
24 Nov - 25 Nov
Econo Lodge Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

13. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
5.8 out of 10, (613 reviews)
"Clean room and nice staff"
United States
Louis
The price is AED 200
AED 240 total
includes taxes & fees
24 Nov - 25 Nov
Quality Inn & Suites Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool

Family-friendly hotels with free breakfast in Santee

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1004)
The price is AED 509
AED 565 total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Santee
View all properties

Family-friendly hotels with pools in Santee

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1004)
The price is AED 509
AED 565 total
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

10/10 Excellent
"Nice new mattress, comfy bed... decent bathroom with nice products... clean and very affordable"
Tina 1-night trip
Posted 4 hours ago
SureStay Hotel by Best Western Manning

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Taw Caw Creek Park. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.