Find Family Hotels in Santee, SC

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Our top choices for Santee family-friendly hotels

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Family vacation paradise with an outdoor pool, fitness center, and quiet, pet-friendly atmosphere for your whole family.
The price is AED 437
AED 485 total
includes taxes & fees
15 Apr - 16 Apr
Best Western Plus Santee Inn

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
The price is AED 478
AED 530 total
includes taxes & fees
26 Apr - 27 Apr
Fairfield Inn & Suites by Marriott Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
The price is AED 410
AED 455 total
includes taxes & fees
4 May - 5 May
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (714 reviews)
The price is AED 231
AED 257 total
includes taxes & fees
12 Apr - 13 Apr
Travelodge by Wyndham Santee

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (41 reviews)
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (312 reviews)
The price is AED 232
AED 258 total
includes taxes & fees
21 Apr - 22 Apr
Econo Lodge Santee

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (187 reviews)
The price is AED 248
AED 268 total
includes taxes & fees
9 Apr - 10 Apr
Peach Tree Inn

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,000 reviews)
The price is AED 290
AED 322 total
includes taxes & fees
9 Apr - 10 Apr
Travelodge by Wyndham Orangeburg

Days Inn by Wyndham St George

Days Inn by Wyndham St George
2.5 star property
St. George
7.6 out of 10, Good, (1,000 reviews)
The price is AED 323
AED 359 total
includes taxes & fees
10 Apr - 11 Apr
Days Inn by Wyndham St George

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (139 reviews)
The price is AED 413
AED 744 total
includes taxes & fees
9 Apr - 10 Apr
Pet friendly country cottage with large fenced-in yard & horses on property
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at family-friendly hotels in Santee

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Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you might want to check out some kid-friendly attractions such as Santee Indian Mound and Fort Watson Site and Orangeburg County Library Mentor Branch. Make sure you have lots of time for activities like Lake Marion and Taw Caw Creek.