Find Family Hotels in Santee, SC

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Check availability on Santee Family Hotels

Tonight
29 Apr - 30 Apr
Tomorrow
30 Apr - 1 May
This weekend
1 May - 3 May
Next weekend
8 May - 10 May

Our top choices for Santee family-friendly hotels

Exterior

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Family vacation paradise with an outdoor pool, fitness center, and quiet, pet-friendly atmosphere for your whole family.
The price is AED 437
AED 485 total
includes taxes & fees
10 May - 11 May
Best Western Plus Santee Inn
Property amenity

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
The price is AED 493
AED 547 total
includes taxes & fees
24 May - 25 May
Fairfield Inn & Suites by Marriott Santee
Seasonal outdoor pool

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,007 reviews)
  • cleanliness
    Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
The price is AED 414
AED 459 total
includes taxes & fees
27 May - 28 May
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, free WiFi, bed sheets

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (724 reviews)
The price is AED 231
AED 257 total
includes taxes & fees
10 May - 11 May
Travelodge by Wyndham Santee
Interior

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (42 reviews)
The price is AED 437
AED 1,301 total
includes taxes & fees
4 May - 5 May
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (313 reviews)
The price is AED 231
AED 256 total
includes taxes & fees
25 May - 26 May
Econo Lodge Santee
Desk, blackout drapes, iron/ironing board, free WiFi

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (199 reviews)
The price is AED 248
AED 268 total
includes taxes & fees
3 May - 4 May
Peach Tree Inn
Free WiFi

Suburban Studios Orangeburg

Suburban Studios Orangeburg
2.0 star property
Orangeburg
6.6 out of 10, (20 reviews)
The price is AED 194
AED 215 total
includes taxes & fees
31 May - 1 Jun
Suburban Studios Orangeburg
Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, iron/ironing board

Days Inn by Wyndham St George

Days Inn by Wyndham St George
2.5 star property
St. George
7.4 out of 10, Good, (1,001 reviews)
The price is AED 367
AED 408 total
includes taxes & fees
6 May - 7 May
Days Inn by Wyndham St George
Property grounds

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (142 reviews)
The price is AED 413
AED 760 total
includes taxes & fees
12 May - 13 May
Pet friendly country cottage with large fenced-in yard & horses on property
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool

Top Santee Hotel Reviews

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

8/10 Good
"The breakfast staff ladies were wonderful. They made the last moments of our stay so much nicer."
Bob 1-night trip
Posted 2 days ago
Hampton Inn Santee-I-95

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Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it's a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Taw Caw Creek. Make sure you have lots of time for activities like Goat Island and Edisto Memorial Gardens.