Search Vacation Homes in Santee

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Vacation Homes in Santee with updated reviews, rates, and availability.

Other property types in Santee

Interior
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
10.0 out of 10, Exceptional, (33)
"We had a great vacation here and Jerry was easily available for any questions we had. This unit had everything we needed for our stay. Great place to stay for family to enjoy time together and go fishing as well."
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
Multiple seating options make this deck a space that your whole group can enjoy.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, (18)
"This place is now our go to on our way and back to and from Cocoa Beach. Love it! Thanks so much Michael"
The price is AED 506
AED 1,357 total
includes taxes & fees
29 May - 30 May
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Exterior
Two Palms Lakehouse in Santee Just minutes from I95
7.6 out of 10, Good, (8)
"Great place for a couple days. We took advantage of the lake. Fishing was great for the grandchildren. I highly recommend this place if you enjoy being by the lake. Thank you."
Two Palms Lakehouse in Santee Just minutes from I95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent reviews of Santee hotels
Expedia verified reviews

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

5/5 Excellent
"The staff was friendly, room clean and breakfast hot. "
A verified traveler stayed at Fairfield Inn & Suites by Marriott Santee
Posted 2 hours ago
Fairfield Inn & Suites by Marriott Santee