Vacation Homes in South Carolina
Compare and save
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Top Cities in South Carolina
Myrtle Beach
Our top choices for South Carolina vacation homes
8.0 out of 10, Very good, (234 reviews)
"Nice place to stay for a vacation! Right on the beach and strip!"
William
The price is AED 298
AED 1,042 total
includes taxes & fees
27 Sep - 28 Sep
3. Beach side vacation house
Beach side vacation houseMyrtle Beach
9.2 out of 10, Wonderful, (64 reviews)
"Nice location, good price"
Tammy W.
The price is AED 327
AED 660 total
includes taxes & fees
28 Sep - 29 Sep
4. Lakefront on Lake Murray, Private Dock, Pet Friendly, Kayaks, 2 King Suites
Lakefront on Lake Murray, Private Dock, Pet Friendly, Kayaks, 2 King SuitesLeesville
9.4 out of 10, Exceptional, (47 reviews)
"Amazing place to unplug and really, really relax. Beautiful house and property."
Lonnie
5. 1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!
1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!Columbia
9.8 out of 10, Exceptional, (49 reviews)
"Great place we enjoyed "
Dawn L.
The price is AED 437
AED 631 total
includes taxes & fees
4 Oct - 5 Oct
6. Luxury Designer Home, Pool & Hot Tub, Elevator, Across From Beach Access
Luxury Designer Home, Pool & Hot Tub, Elevator, Across From Beach AccessIsle of Palms
10.0 out of 10, Exceptional, (66 reviews)
"Awesome place "
Eddie M.
7. Luxury Retreat with 4 King Suites
Luxury Retreat with 4 King SuitesDowntown Charleston
10.0 out of 10, Exceptional, (25 reviews)
"Place was spectacular."
Daryl L.
8. Pier View Home | Sleeps 10 | Pet Friendly
Pier View Home | Sleeps 10 | Pet FriendlyMyrtle Beach
9.0 out of 10, Wonderful, (14 reviews)
"Home away from home! Perfect proximity to attractions. Very accommodating, clean & spacious. "
Stephanie J.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find vacation rentals that suit your style
Cabins
Apartments
Save an average of 15% on thousands of hotels when you're signed in
Top South Carolina Hotel Reviews
Hilton Grand Vacations Club Ocean 22 Myrtle Beach.
10/10 Excellent
Explore a world of travel with Expedia
- Edgemoor Hotels
- Apartments in Piedmont
- Motels in Blenheim
- 3 Star Hotels in Hemingway
- Vacation Homes in Irmo
- Cottages in Denmark
- Apartments in North Augusta
- Accor Hotels in Myrtle Beach
- Fairfax Hotels
- Cabin Rentals in Little Mountain
- Motel 6 Hotels in Conway
- Myrtle Beach Hotels
- Cabin Rentals in Mount Pleasant
- Hotels with smoking rooms in Columbia
- Cabin Rentals in Townville
- Apartments in Blythewood
- Motels in Sumter
- Marriott Hotels & Resorts in Honea Path
- Resorts & Hotels with Spas in Little River
- Cottages in Boiling Springs
- Villas in Liberty
- Hilton Hotels in Seabrook Island
- 4 Star Hotels in Saluda
- Condo Rentals in Folly Beach
- Hilton Hotels in Ridgeville
- 4 Star Hotels in Walterboro
- Apartments in McConnells
- B&B in Camden
- Best Western Hotels in Florence
- Resorts in Port Royal
- Cabin Rentals in Nesmith
- Wyndham Hotels in Seneca
- Hotels with a Pool in North Charleston
- Villas in Hilton Head Island
- Villas in Saint Helena Island
- Cabin Rentals in Union
- B&B in Pawleys Island
- B&B in West Columbia
- Apartments in Santee
- Marriott Hotels & Resorts in McCormick
- Apartments in Ballentine
- Condo Rentals in Harbor Island
- Marriott Hotels & Resorts in Georgetown
- Romantic Hotels in Kiawah Island
- Villas in Seabrook Island
- Walt Disney World Resort in Hilton Head Island
- Cabin Rentals in North Augusta
- 4 Star Hotels in Branchville
- 4 Star Hotels in York
- Condo Rentals in Bluffton
- 5 Star Hotels in Landrum
- Cabin Rentals in Greenwood
- Apartments in Duncan
- Cabin Rentals in Edgefield
- Rv Parks in Gaffney
- Rv Parks in Trenton
- Hilton Hotels in Harleyville
- Fingerville Hotels
- Cabin Rentals in Joanna
- Apartments in Summerville
- Hotels with WiFi in North Charleston
- B&B in Andrews
- Business Hotels in Columbia
- Saint Helena Island Hotels
- Waterpark Hotels in Charleston
- Cottages in Chapin
- 5 Star Hotels in Beaufort
- Villas in Mount Pleasant
- Condo Rentals in Santee
- Blenheim Hotels
- Easley Hotels
- Vacation Homes in Myrtle Beach
- Flights from Elloree
- Flights from Inman
- Flights to Murrells Inlet
- Flights to Hardeeville
- Flights from Gilbert
- Flights from Murrells Inlet
- Flights from Aynor
- Flights from Walhalla
- Flights from Liberty
- Flights to Edgemoor
- Flights to Elloree
- Flights to Lugoff
- Flights to Kiawah Island
- Flights to Garden City