Top Wyndham Hotels in Seneca, SC

A calm lake with mountains in the background.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Save an average of 15% on thousands of hotels when you're signed in

Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

10/10 Excellent

"Staff were nice and accommodating"

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

10/10 Excellent

"Loved the lake house. The view of the lake from the house is beautiful. The dock was in great shape and we enjoyed kayaking and swimming in the warm water. It was very quiet and peaceful. The home had everything we needed for a two day getaway. We enjoyed eating our meals in the screened in porch with a view of the lake. Communication and getting in and out of the home was easy. We’d stay here again and have no hesitation recommending the home. Great value! Wonderful memories made!"

Quality Inn Seneca US-123

10/10 Excellent

"Convenient location. Reasonably priced. Staff is very friendly and helpful."

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

10/10 Excellent

"Amazing lake views and beautiful home!"

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

10/10 Excellent

"Fantastic!"

Beautiful large family home with dock on Lake Keowee!

10/10 Excellent

"Large lake house with a beautiful view. We took 16 people (8 adults & 8 children 2-12yr) and had room for everyone. Kitchen was well stocked with pots and pans. Had to run the dishwasher twice a day for everyone. Had plenty of plates but sometimes we had to wash forks and spoons. Plenty of lake towels. Comes with one bath towel, hand towel and washcloth per person. Two washing machines and dryers there! They had a highchair and pack n play at the house.Games were a great plus. Early risers could play in the garage - ping pong & foosball table. Downstairs had large chess, foosball, pool table, large connect four and corn hole. Has two refrigerators which was wonderful! We cook all our meals so fridge space is a necessity.Back sun porch had a large table and chairs. We were able to eat our meals together out there. It got a little warm but there were two box fans at the house.We rented a boat from High Rock - boat was older and cover leaked. (We had rain every day.) We got a tube but it was only good for two people. Boat wasn’t as good as we expected. (Large tri-toon that held 18)Swimming from the dock was great! Would suggest you bring life jackets and floats to use. House is in a cove and you don’t have to stress as much about boat traffic. Has kayaks and canoes. We used the kayaks a lot. Only two kayak paddles.It is about 20-25 minutes to grocery/walmart.Overall - it was a great week! Wouldn’t hesitate to rent again. Scott was great to communicate with."

Lakefront home with private beach & unbelievable sunsets on Lake Keowee

10/10 Excellent

"We had a fantastic stay! The house was clean, comfortable, and the dock was perfect for fishing, kayaking, and paddleboarding. Our boys had an absolute blast tubing on the lake and exploring the nearby island was one of the highlights of the trip. We made so many great family memories and would definitely stay here again. Highly recommend!"

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

10/10 Excellent

"Great property I wish there was more lighting around the stairs and where you park at night think that would be helpful. Very clean."

Fabulous Tiny House with AC in charming Seneca

8/10 Good

"Pros: property was stunning, felt very private. Extremely easy entry and home was spotless, temperature inside was set perfectly (no needing to turn on air and wait for it to cool down), stocked kitchen with everything you could need, utensils, cups, napkins, plates, soap, etc., bathroom was also stocked with towels, washcloths, soap, shampoo, blow dryer, toilet paper, there was a blackstone outside on deck (wish we had known this!) keurig (along with provided kcups), & microwave. All bed linens as well as extra pillows provided. My husband and I were very happy with this tiny home!Cons: wifi did not work, and after a day of host trying to fix it remotely it still never worked, listing says it sleeps 4 however I do not see how this is possible, theres one queen bed, in my opinion this is a perfect home for two people. Speaking of the bed it is up a set of very steep steps, something to keep in mind if your not spring chickens like ourselves... we felt very wobbly and scared climbing up and down everytimeAll in all I would definitely recommend this home, I am sure the host will fix the wifi, he made it right with us because he couldn't fix it. I am sure you'd enjoy this home as long as your comfortable with the steep steps to the bed"

Explore a world of travel with Expedia

Clemson Vacations

Find all hotels by Wyndham Hotels in Seneca, SC

Change your mind

Treat yourself

Be picky

Check prices for these dates

Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

Quality Inn Seneca US-123

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

Beautiful large family home with dock on Lake Keowee!

Lakefront home with private beach & unbelievable sunsets on Lake Keowee

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fabulous Tiny House with AC in charming Seneca

Explore a world of travel with Expedia