Santo Spirito Vacations

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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Uffizi Gallery and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Find hotels in Historic Centre of Florence

Santo Spirito Hotel Deals

Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AED 799 per night from Jul 6 to Jul 7
AED 799
AED 937 total
6 Jul - 7 Jul
includes taxes & fees
9.6/10 Exceptional! (519 reviews)
"All good"

Reviewed on 28 May 2025

Hotel Horto Convento
Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
9.2/10 Wonderful! (985 reviews)
"Highly recommend! AMAZING location - lots of cute coffee shops and restaurants nearby. Very clean. Lots of room. The staff working here are also super friendly and went out of their way to welcome me!"

Reviewed on 1 June 2025

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Palazzo Mannaioni Suites
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
The price is AED 627 per night from Jun 8 to Jun 9
AED 627
AED 749 total
8 Jun - 9 Jun
includes taxes & fees
8.4/10 Very Good! (988 reviews)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice"

Reviewed on 31 May 2025

UNA HOTELS Vittoria Firenze
See all 458 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santo Spirito

Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the churches in this vibrant area.

Brancacci Chapel