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Vacation Homes in Scott County

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Our top choices for Scott County vacation homes

1. “Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

“Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses
Cape Girardeau
9.4 out of 10, Exceptional, (15 reviews)
"Clean, homey, family friendly!"
United States
Merry J.
“Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

2. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO
Dexter
10.0 out of 10, Exceptional, (4 reviews)
"Perfect place for our stay on the way to North Carolina! Clean, cozy and convenient!"
United States
Robert G.
The price is AED 492
AED 577 total
includes taxes & fees
16 Nov - 17 Nov
The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

3. “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (51 reviews)
"Spectacular place and great host! Highly recommend!"
United States
Eric P.
“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

4. Urban 2-bedroom Escape in Downtown Cape Girardeau

Urban 2-bedroom Escape in Downtown Cape Girardeau
Cape Girardeau
10.0 out of 10, Exceptional, (12 reviews)
"Great location and a cozy stay for a weekend trip. Highly recommend. "
United States
Connor c.
Urban 2-bedroom Escape in Downtown Cape Girardeau

5. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (15 reviews)
"The place was nice and clean and the hosts were great. Would definitely stay there again!"
United States
Katlynn R.
The price is AED 505
AED 1,003 total
includes taxes & fees
24 Nov - 25 Nov
Stunning 2 bedroom in town, close to Shawnee National Forest

6. 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Cape Girardeau
9.8 out of 10, Exceptional, (40 reviews)
"We truly enjoyed our stay and we would stay there again."
United States
Daniel W.
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

7. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 368 total
includes taxes & fees
13 Nov - 14 Nov
Little Blue Cottage on Spanish

8. Charming, historic Fuerth House in Downtown Cape Girardeau, 2 bedrooms, 1 bath.

Charming, historic Fuerth House in Downtown Cape Girardeau, 2 bedrooms, 1 bath.
Cape Girardeau
10.0 out of 10, Exceptional, (5 reviews)
Charming, historic Fuerth House in Downtown Cape Girardeau, 2 bedrooms, 1 bath.

9. Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
10.0 out of 10, Exceptional, (21 reviews)
"Everything was beautiful, and although we weren’t there for a long time, enjoyed an Incredible sleep in the most comfortable beds!"
United States
Rachel H.
The price is AED 652
AED 1,225 total
includes taxes & fees
15 Nov - 16 Nov
Magical Victorian near hiking / wine trail

10. Wandering the wineries or hitting the hills? We got you! Come stay!

Wandering the wineries or hitting the hills? We got you! Come stay!
Tamms
10.0 out of 10, Exceptional, (36 reviews)
"Great communication and perfect location for what we were looking for."
United States
David P.
Wandering the wineries or hitting the hills? We got you! Come stay!

11. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is AED 591
AED 816 total
includes taxes & fees
13 Nov - 14 Nov
The Little Cape Lofted Cottage | Creek & Nature

12. Quaint, Beautiful Home next to SEMO and Hospital

Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
9.8 out of 10, Exceptional, (52 reviews)
"Would stay here again!"
United States
Michelle C.
Quaint, Beautiful Home next to SEMO and Hospital

13. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is AED 1,653
AED 2,413 total
includes taxes & fees
12 Dec - 13 Dec
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

14. Deck & Large Yard! Family Haven in Cape Girardeau

Deck & Large Yard! Family Haven in Cape Girardeau
Cape Girardeau
9.6 out of 10, Exceptional, (4 reviews)
"Fantastic Property!!!"
United States
Kerwin U.
Deck & Large Yard! Family Haven in Cape Girardeau

15. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
8.0 out of 10, Very good, (40 reviews)
"Overall, it was a good experience. I would stay again."
United States
Tammy G.
The price is AED 393
AED 756 total
includes taxes & fees
15 Nov - 16 Nov
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

16. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AED 658
AED 1,103 total
includes taxes & fees
15 Nov - 16 Nov
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

17. Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri
Jackson
9.8 out of 10, Exceptional, (8 reviews)
"Nice, clean place, a home away from Home for the entire family."
United States
John B M.
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

18. Charming 2-bedroom house in delightful Jackson with AC, WiFi

Charming 2-bedroom house in delightful Jackson with AC, WiFi
Jackson
10.0 out of 10, Exceptional, (8 reviews)
"Absolutely loved the location quiet country location but easy to get to everything. If we are in the area again would definitely stay here again"
United States
Tom
Charming 2-bedroom house in delightful Jackson with AC, WiFi

19. Charming 3-bedroom house in delightful Advance with AC, WiFi

Charming 3-bedroom house in delightful Advance with AC, WiFi
Advance
10.0 out of 10, Exceptional, (13 reviews)
"Very nice and cute house with plenty of room and amenities. Would definitely stay here again!"
United States
Dakota D.
Charming 3-bedroom house in delightful Advance with AC, WiFi

20. Charming 3-bedroom house near downtown

Charming 3-bedroom house near downtown
Cape Girardeau
10.0 out of 10, Exceptional, (4 reviews)
"Great house for our stay in Cape! Close to downtown and SEMO. We would definitely stay here again! Sydney was great to communicate with!"
United States
Jason L.
Charming 3-bedroom house near downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Scott County Hotel Reviews

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