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Check prices for these dates

Next weekend
23 Jan - 25 Jan
In two weeks
30 Jan - 1 Feb
In one month
13 Feb - 15 Feb
In two months
13 Mar - 15 Mar

Our top choices for East Prairie apartments

Outdoor dining

Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (1 review)
"Nice place. "
United States
Andrew E.
The price is AED 367
AED 596 total
includes taxes & fees
16 Jan - 17 Jan
Vacation rental attached to our house out in the country.
Smart TV

Tranquil charming Tiny House in Clinton

Tranquil charming Tiny House in Clinton
2.0 star property
Clinton
The price is AED 331
AED 551 total
includes taxes & fees
15 Feb - 16 Feb
Tranquil charming Tiny House in Clinton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Prairie Hotel Reviews

Best Western Plus Sikeston

Best Western Plus Sikeston

10/10 Excellent
"The breakfast menu was fresh except for some of the Half and Half creamer was curdled, spoiled. And the coffee was luke warm."
Michael 1-night trip
Posted 4 days ago
Best Western Plus Sikeston

Frequently asked questions

What's it like to stay at an apartment in East Prairie?
You might not have many choices within the heart of East Prairie, but Expedia can help you find accommodations in the area with similar amenities to an apartment. When you search on Expedia, you can use the filters to search for conveniences you might find in an apartment like a kitchen. Even filter by similar property types like condos, vacation homes, or cottages.
Why would you choose an apartment versus a traditional hotel?
An apartment features a kitchen for convenient meals, and usually is more spacious than a traditional hotel room. Apartments are a good option for couples who want a more local feel, and also for families wanting the conveniences of home.
What's a favorite apartment for a stay in East Prairie?
Below is a popular apartment in the area to consider: Dog-friendly Cabin w/ Cornhole & Fire Pit: It's situated in Tiptonville, 29.7 mi/47.7 km from East Prairie.
What will the weather be like when I travel to East Prairie?
Weather is only one factor, but it can really affect your travel plans, especially when you're planning an extended stay in East Prairie. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.
What are the must-see places to visit in East Prairie?
Big Oak Tree State Park and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you'll find Sikeston Depot Museum and New Madrid Historical Museum.
What's the best way to get to and around East Prairie?
Knowing a bit about the transportation options can make your trip smoother when you get to your destination. Fly into Cairo, IL (CIR-Cairo Regional), which is located 21.4 mi (34.4 km) away from the city center. You can also search for flights into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 32.4 mi (52.2 km) away. If you'd like to explore around the area, consider renting a car to take in more sights.