Find all hotels by Motel 6 in Sikeston, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
24 Aug - 25 AugTomorrow
25 Aug - 26 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sep - 6 Sep
Save an average of 15% on thousands of hotels when you're signed in
Top Sikeston Hotel Reviews
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"The room was clean and quiet. Staff was friendly and professional and helpful. Breakfast was very good with plenty of options. Second time I have stayed here and felt safe as a woman traveling with her daughter. Only minor complaint is that the pillows aren't the best. Recommend bringing your own from home if you can."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Clean rooms, friendly staff, I would definitely stay here again next time I’m in town."
Best Western Plus Sikeston I-55
10/10 Excellent
"I really loved everything about my stay and the hotel in general. Nice Job"
The Riverview
8/10 Good
"Nice view of the river. The staff was nice."
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Great value, very clean and breakfast was actually good."
Super 8 by Wyndham Sikeston/Miner Area
10/10 Excellent
"Good price."
Explore a world of travel with Expedia
- Independent Hotels in Sikeston
- Wyndham Hotels in Oran
- Premier Inn Hotels in Cape Girardeau
- Best Western Hotels in East Prairie
- Catron Hotels
- Cheap Hotels in Dexter
- Aimbridge Hospitality Hotels in Cape Girardeau
- Cabin Rentals in New Madrid
- Cheap Hotels in Sikeston
- Hotels with a Pool in Charleston
- Drury Inn & Suites Hotels in Sikeston
- Cabin Rentals in East Prairie
- Aimbridge Hospitality Hotels in Oran
- 2 Star Hotels in Dexter
- Aimbridge Hospitality Hotels in Bertrand
- 2 Star Hotels in Bertrand
- Aparthotels in Sikeston
- Cottages in Catron
- 4 Star Hotels in Bloomfield
- Hotel Wedding Venues Hotels in Dexter
- Premier Inn Hotels in Malden
- New Madrid Hotels
- Motels in Charleston
- Hilton Hotels in Sikeston
- 3 Star Hotels in Bloomfield
- 5 Star Hotels in New Madrid
- Cottages in Sikeston
- Cabin Rentals in Bloomfield
- 2 Star Hotels in Charleston
- Country Hearth Inn Hotels in Bertrand
- Best Western Hotels in Oran
- 4 Star Hotels in Dexter
- Rv Parks in Sikeston
- Blodgett Hotels
- Apartments in East Prairie
- Independent Hotels in Wardell
- 3 Star Hotels in Catron
- Best Western Hotels in Bloomfield
- Cabin Rentals in Dexter
- Hotels with smoking rooms in Sikeston
- 3 Star Hotels in Bertrand
- Best Western Hotels in Charleston
- 5 Star Hotels in Canalou
- Aimbridge Hospitality Hotels in Wappapello
- Motels in Oran
- Hotel Wedding Venues Hotels in Sikeston
- Red Carpet Inn Hotels in Bloomfield
- Hotels with a Pool in Sikeston
- Cabin Rentals in Sikeston
- Apartments in Dexter
- Drury Inn & Suites Hotels in Cape Girardeau
- Hotels with an Indoor Pool in Sikeston
- Motels in Bloomfield
- Independent Hotels in Marble Hill
- B&B in Sikeston
- 2 Star Hotels in East Prairie
- Wyndham Hotels in Bloomfield
- 3 Star Hotels in Charleston
- Drury Inn & Suites Hotels in Jackson
- 4 Star Hotels in Oran
- Wyndham Hotels in Bertrand
- Flights from Vopnafjordur (VPN) to Cape Girardeau (CGI)
- Flights from Bridgeport (BDR) to Cape Girardeau (CGI)
- Flights from Stuttgart (STR) to Cape Girardeau (CGI)
- Flights from Gulfport (GPT) to Cape Girardeau (CGI)
- Flights from Palm Springs (PSP) to Cape Girardeau (CGI)
- Flights from Lac La Martre (YLE) to Cape Girardeau (CGI)
- Flights from Milan (MIL) to Cape Girardeau (CGI)
- Flights from Sikeston
- Flights from Dexter
- Flights to Bertrand
- Flights from Cape Girardeau Municipal
- Flights from Orlando (MCO) to Cape Girardeau (CGI)
- Flights from Charleston
- Flights from Leeds (LBA) to Cape Girardeau (CGI)
- Flights from Cat Cay (CXY) to Cape Girardeau (CGI)
- Flights from White Plains (HPN) to Cape Girardeau (CGI)
- Flights from Oran
- Flights from Blodgett
- Flights from Louisville (LOU) to Cape Girardeau (CGI)
- Flights from Muskegon (MKG) to Cape Girardeau (CGI)
- Flights from Bellingham (BLI) to Cape Girardeau (CGI)
- Flights from Yakima (YKM) to Cape Girardeau (CGI)
- Flights from Corinth (CRX) to Cape Girardeau (CGI)
- Flights from Cold Bay (CDB) to Cape Girardeau (CGI)
- Flights from Baltimore (BWI) to Sikeston (SIK)
- Flights from East Prairie
- Flights from Cortez (CEZ) to Cape Girardeau (CGI)
- Flights from Eek (EEK) to Cape Girardeau (CGI)
- Flights from Catron
- Flights from New Madrid
- Flights from Bloomfield
- Flights from Grand Island (GRI) to Cape Girardeau (CGI)
- Flights from Nairobi (NBO) to Cape Girardeau (CGI)
- Flights from Qingdao (TAO) to Cape Girardeau (CGI)
- Flights from Argostolion (EFL) to Cape Girardeau (CGI)
- Flights from Bowling Green (BWG) to Sikeston (SIK)