A calm lake with mountains in the background.

Find Adventure Hotels in Seneca, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Seneca Adventure Hotels

Our top choices for Seneca adventure hotels

Free daily on-the-go breakfast

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (760 reviews)
"Staff was very nice and accommodating, we moved rooms from the back to the front due to noise, the 2nd room we were in the bath tub and sink took forever to drain so you were standing in a puddle the whole time you showered."
United States
Karl
The price is AED 256
AED 282 total
includes taxes & fees
13 Jul - 14 Jul
Days Inn by Wyndham Seneca / Clemson Area
Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (675 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is AED 356
AED 392 total
includes taxes & fees
12 Jul - 13 Jul
Best Western Seneca-Clemson
Terrace/patio

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Seneca
The price is AED 621
AED 1,213 total
includes taxes & fees
12 Jul - 13 Jul
Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University
Smart TV, video games, table tennis

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Seneca
10.0 out of 10, Exceptional, (25 reviews)
"Very nice accommodations and great location for stay in Clemson. "
United States
Marisa G.
The price is AED 480
AED 1,413 total
includes taxes & fees
15 Jul - 16 Jul
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Fridge, microwave, oven, stovetop

Carolina Cottage Retreat-12 Minutes from Clemson University

Carolina Cottage Retreat-12 Minutes from Clemson University
Seneca
The price is AED 714
AED 1,355 total
includes taxes & fees
13 Jul - 14 Jul
Carolina Cottage Retreat-12 Minutes from Clemson University
Exterior

Adorable 2-bedroom 1- full bath mobile home with AC close to Lake Keowee, SC

Adorable 2-bedroom 1- full bath mobile home with AC close to Lake Keowee, SC
Seneca
8.8 out of 10, Excellent, (3 reviews)
"A little further out than I thought. Other than that, everything else was great. Would stay there again. The host was super nice and answered any question that I had. I had a very pleasant stay."
United States
Randy M.
The price is AED 430
AED 659 total
includes taxes & fees
16 Jul - 17 Jul
Adorable 2-bedroom 1- full bath mobile home with AC close to Lake Keowee, SC
Fridge, microwave, oven, stovetop

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.6 out of 10, Exceptional, (10 reviews)
"This was a WONDERFUL place, very comfortable and welcoming! The host was accommodating and super responsive! I would stay here again! "
United States
Shauna S.
The price is AED 826
AED 1,309 total
includes taxes & fees
12 Jul - 13 Jul
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Smart TV, fireplace, books

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (20 reviews)
"Immaculate home very close to cute shops and restaurants. Perfect setup for our dog! "
United States
Joy B.
The price is AED 559
AED 1,216 total
includes taxes & fees
15 Jul - 16 Jul
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Property grounds

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Seneca
9.8 out of 10, Exceptional, (62 reviews)
"We had a beautiful stay over Thanksgiving in this very cozy lake house. "
United States
Felicia L.
The price is AED 1,047
AED 1,988 total
includes taxes & fees
22 Jul - 23 Jul
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Microwave, oven, stovetop, dishwasher

The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is AED 1,593
AED 2,884 total
includes taxes & fees
21 Jul - 22 Jul
The Big Golf House- 10 miles to Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Seneca Hotel Reviews

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

8/10 Good
"Just overnight stay, calling front desk didn’t provide help or the best rate, but Expedia did, and the lady the morning of check out was awesome! Will stay again."
Christopher 1-night trip
Posted 9 days ago
Days Inn by Wyndham Seneca / Clemson Area
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

10/10 Excellent
"Very quiet and peaceful! Grill was great! Great location."
Robert C. 3-night trip
Posted 1 month ago
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Explore a world of travel with Expedia