Seneca Vacations
Book a Hotel + Flight together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to AED 148 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Find the Best Seneca Vacation Packages
Seneca Hotel Deals
Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is AED 400 per night from May 20 to May 21
AED 400
AED 494 total
20 May - 21 May
includes taxes & fees
8.8/10 Excellent! (871 reviews)
"Great Location"
Reviewed on 17 May 2025
Tru by Hilton Seneca Clemson
13050 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
The price is AED 403 per night from Jun 1 to Jun 2
AED 403
AED 443 total
1 Jun - 2 Jun
includes taxes & fees
9.2/10 Wonderful! (714 reviews)
"We love this hotel when visiting family in the area. Good location, fun atmosphere, excellent staff."
Reviewed on 9 May 2025
Postcard Cabins Lake Hartwell
299 Outpost Rd, Seneca, SC
The price is AED 327 per night from Jun 1 to Jun 2
AED 327
AED 501 total
1 Jun - 2 Jun
includes taxes & fees
10/10 Exceptional! (6 reviews)
"The view of the woods out of the large window as you lay in bed is relaxing and surprising even at night."
Reviewed on 9 May 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.