The Best Family Hotels in Sikeston, MO from AED 239 in 2026

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Our top choices for Sikeston family-friendly hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

1. Drury Inn & Suites Sikeston, MO

Sikeston

Children's paradise awaits with splash-worthy indoor and outdoor pools, free breakfast buffet, and family-focused amenities all day long.

AED 345

AED 397 total

includes taxes & fees

11 Oct - 12 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

2. Hampton Inn Sikeston

Sikeston

AED 387

AED 440 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

AED 364

AED 414 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

4. Best Western Plus Sikeston I-55

Sikeston

AED 311

AED 355 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

5. TownePlace Suites by Marriott Sikeston

Sikeston

AED 386

AED 437 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious lobby with a central atrium, a piano, and a reception desk.

6. Days Inn and Suites by Wyndham Sikeston

Sikeston

AED 244

AED 278 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

7. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

AED 210

AED 239 total

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

8. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

A family paradise with splash-worthy fun awaits, where complimentary breakfast and an indoor pool create lasting memories for all ages.

AED 367

AED 414 total

includes taxes & fees

8 Oct - 9 Oct

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Choose what matters most at family-friendly hotels in Sikeston

Breakfast included

Pool

All-inclusive

4 stars

5 stars

Family-friendly hotels with free breakfast in Sikeston

Drury Inn & Suites Sikeston, MO

Sikeston

AED 345

AED 397 total

includes taxes & fees

11 Oct - 12 Oct

Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

AED 367

AED 414 total

includes taxes & fees

8 Oct - 9 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

AED 372

AED 419 total

includes taxes & fees

8 Oct - 9 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

AED 293

AED 318 total

includes taxes & fees

2 Nov - 3 Nov

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

Pear Tree Inn Cape Girardeau West

Cape Girardeau

AED 264

AED 298 total

includes taxes & fees

11 Oct - 12 Oct

A building with a fountain and flower beds in front.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

The Riverstone Hotel Charleston-Sikeston

Charleston

AED 244

AED 271 total

includes taxes & fees

6 Oct - 7 Oct

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

AED 219

AED 243 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

Comfort Suites Jackson-Cape Girardeau

Jackson

AED 278

AED 301 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

Econo Lodge Dexter

Dexter

AED 187

AED 210 total

includes taxes & fees

2 Nov - 3 Nov

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

Dexter Inn

Dexter

AED 253

AED 285 total

includes taxes & fees

17 Oct - 18 Oct

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