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Check prices for these dates

In two weeks
10 Jul - 12 Jul
In two months
21 Aug - 23 Aug
In three months
18 Sep - 20 Sep
In four months
16 Oct - 18 Oct

Our top choices for Southeast Missouri vacation homes

Terrace/patio

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (5 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
United States
Chris
The price is AED 817
AED 1,244 total
includes taxes & fees
29 Jun - 30 Jun
Tiny Houses of French Village
Interior

Charming 2-bedroom house with AC, WiFi in serene Van Buren

Charming 2-bedroom house with AC, WiFi in serene Van Buren
Van Buren
8.8 out of 10, Excellent, (20 reviews)
"It was beautiful and homey. We really enjoyed our stay. "
United States
Jessica
The price is AED 257
AED 620 total
includes taxes & fees
2 Jul - 3 Jul
Charming 2-bedroom house with AC, WiFi in serene Van Buren
Outdoor spa tub

Retreat Air - King Bed, Hot Tub & No cleaning fee

Retreat Air - King Bed, Hot Tub & No cleaning fee
Perryville
10.0 out of 10, Exceptional, (7 reviews)
"Great host. Would stay again."
United States
Chris E.
The price is AED 514
AED 631 total
includes taxes & fees
3 Jul - 4 Jul
Retreat Air - King Bed, Hot Tub & No cleaning fee
Exterior

Secluded Log Cabin

Secluded Log Cabin
Annapolis
9.8 out of 10, Exceptional, (28 reviews)
"Stay was fine, nice peaceful setting, enjoyed our stay and would come back or recommend to others, thank you"
United States
Glen J.
The price is AED 422
AED 774 total
includes taxes & fees
6 Jul - 7 Jul
Secluded Log Cabin
Dining

Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (14 reviews)
"Beautiful and perfect for travelers!!!!!"
United States
Elizabeth
The price is AED 312
AED 737 total
includes taxes & fees
12 Jul - 13 Jul
Cozy 1-bedroom house with AC and WiFi in charming Farmington
Property grounds

Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (98 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveler
The price is AED 386
AED 481 total
includes taxes & fees
29 Jun - 30 Jun
Get Away Acres 1/2 mile off highway 60 extra sanitized
Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
8 Jul - 9 Jul
Little Blue Cottage on Spanish
Fridge, microwave, oven, stovetop

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (22 reviews)
"Great little place and perfect forOur stay "
United States
kara S.
The price is AED 444
AED 872 total
includes taxes & fees
30 Jun - 1 Jul
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Terrace/patio

Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (36 reviews)
"Great stay, very clean and comfortable."
United States
Chris G.
The price is AED 459
AED 560 total
includes taxes & fees
28 Jun - 29 Jun
Clifford's Country Cottage
Fridge, microwave, oven, stovetop

Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.8 out of 10, Exceptional, (31 reviews)
"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"
United States
Jody C.
The price is AED 397
AED 931 total
includes taxes & fees
26 Jun - 27 Jun
Cozy Three bedroom home in Central Farmington
Smart TV, fireplace, books

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.0 out of 10, Wonderful, (7 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
The price is AED 248
AED 543 total
includes taxes & fees
29 Jun - 30 Jun
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Exterior detail

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
8.8 out of 10, Excellent, (12 reviews)
"The house was very clean and nicely decorated. The huge TV in the living room was a plus and the mattress was very comfortable. We would stay again!"
United States
Brian
The price is AED 422
AED 1,051 total
includes taxes & fees
6 Jul - 7 Jul
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Terrace/patio

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Ironton
10.0 out of 10, Exceptional, (37 reviews)
"Great place to stay!"
United States
Derek R.
The price is AED 497
AED 1,008 total
includes taxes & fees
14 Jul - 15 Jul
*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Beach

Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (47 reviews)
"We loved the location and the charm. And the chickens and friendly kitty were a bonus. Great stay. "
United States
Jenny R.
The price is AED 474
AED 911 total
includes taxes & fees
29 Jun - 30 Jun
Your home away from home in downtown, historic Farmington!
Smart TV, books

Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (14 reviews)
"Excellent! Will stay again!"
United States
Michael M.
The price is AED 547
AED 939 total
includes taxes & fees
6 Jul - 7 Jul
Doc's Cottage - A-Frame in Piggott, AR
Interior

The Sutton House 2 blocks from Main Street & Courthouse Square

The Sutton House 2 blocks from Main Street & Courthouse Square
Ironton
10.0 out of 10, Exceptional, (61 reviews)
"We enjoyed our stay. Nice big comfortable beds. Short walk to coffee shop & short drive to several nice hiking spots. "
United States
Nicole K.
The price is AED 918
AED 1,135 total
includes taxes & fees
29 Jun - 30 Jun
The Sutton House 2 blocks from Main Street & Courthouse Square
Exterior

Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.
Bloomsdale
10.0 out of 10, Exceptional, (16 reviews)
"Nice house to have a small Christmas get together with great hosts."
United States
Sean D.
The price is AED 661
AED 1,019 total
includes taxes & fees
28 Jun - 29 Jun
Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.
Free WiFi, bed sheets

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
The price is AED 347
AED 794 total
includes taxes & fees
29 Jun - 30 Jun
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Property grounds

King Bed, game room minutes away from downtown, golf courses + BIG back yard

King Bed, game room minutes away from downtown, golf courses + BIG back yard
Farmington
10.0 out of 10, Exceptional, (29 reviews)
"Everything about this property was amazing and perfect for our family! They were so helpful with everything and our kids loved it here!!"
United States
Heaven B.
The price is AED 580
AED 1,145 total
includes taxes & fees
28 Jun - 29 Jun
King Bed, game room minutes away from downtown, golf courses + BIG back yard
Exterior detail

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (10 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
The price is AED 444
AED 868 total
includes taxes & fees
18 Jul - 19 Jul
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Hotel was clean and quiet. Beds were comfortable, and breakfast was good, with many hot and cold items to choose from."
Cynthia 1-night trip
Posted 2 hours ago
Baymont Inn and Suites by Wyndham Farmington, MO