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Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for Southeast Missouri vacation homes

A modern kitchen with grey cabinets, a black refrigerator, and a microwave.

1. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (30 reviews)
"Very nice stay we enjoyed would definitely stay again"
United States
Ben C.
The price is AED 444
AED 886 total
includes taxes & fees
11 Oct - 12 Oct
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
A bedroom with a bed, a bench, and a ceiling fan.

2. AV Bungalows #9B

AV Bungalows #9B
Arcadia
10.0 out of 10, Exceptional, (2 reviews)
"My husband and I really enjoyed our stay! The Bungalow was perfect for us and will definitely be staying again when we come back to Arcadia!!"
United States
Theresa R.
The price is AED 498
AED 613 total
includes taxes & fees
11 Oct - 12 Oct
AV Bungalows #9B
A compact living space with a sofa, dining table, kitchen area, and a ceiling fan.

3. Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.2 out of 10, Wonderful, (10 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
The price is AED 290
AED 592 total
includes taxes & fees
26 Oct - 27 Oct
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
A wooden deck with steps leading to a house, surrounded by trees.

4. Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (101 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveler
The price is AED 386
AED 481 total
includes taxes & fees
12 Oct - 13 Oct
Get Away Acres 1/2 mile off highway 60 extra sanitized
A wooden deck with outdoor seating and a fire pit, surrounded by trees.

5. The Stonehouse - Private Hot Tub - Sleeps 5

The Stonehouse - Private Hot Tub - Sleeps 5
Fredericktown
9.8 out of 10, Exceptional, (8 reviews)
"The Stonehouse was every bit as cute and comfortable as expected! We enjoyed staying here as a great base for hiking in the area. The tiny town is a neat complex of different types of place to stay plus the Station coffee house was great to have in walking distance. "
United States
Beth A.
The Stonehouse - Private Hot Tub - Sleeps 5
A kitchen with white cabinets, a wooden dining table, a built-in stove, and a trash can.

6. Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.8 out of 10, Exceptional, (37 reviews)
"Super cute house in a great location."
United States
Theresa
The price is AED 397
AED 942 total
includes taxes & fees
20 Oct - 21 Oct
Cozy Three bedroom home in Central Farmington
A covered outdoor seating area with a table and chairs, string lights, and a gravel ground.

7. Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (44 reviews)
"This place is a gem! Country setting, but only a few minutes from shops and restaurants. New and extremely well stocked. Perfect for a couple looking to get away. Host is super responsive and accommodating! Will definitely be back."
United States
Philip
The price is AED 459
AED 564 total
includes taxes & fees
20 Oct - 21 Oct
Clifford's Country Cottage
A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

8. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
The price is AED 485
AED 909 total
includes taxes & fees
11 Oct - 12 Oct
Hunting / Fishing Cabin at Lake Wappapello
A person sitting on rocks by a flowing river surrounded by greenery.

9. Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (51 reviews)
"Great location. We loved watching the chickens."
United States
Emily N.
The price is AED 474
AED 922 total
includes taxes & fees
11 Oct - 12 Oct
Your home away from home in downtown, historic Farmington!
A porch with four green Adirondack chairs, a small table, and string lights.

10. *State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Ironton
10.0 out of 10, Exceptional, (41 reviews)
"Great place to stay!"
United States
Derek R.
The price is AED 554
AED 1,112 total
includes taxes & fees
13 Oct - 14 Oct
*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
A window with a vase of flowers and a book on a wooden table.

11. The Sutton House 2 blocks from Main Street & Courthouse Square

The Sutton House 2 blocks from Main Street & Courthouse Square
Ironton
10.0 out of 10, Exceptional, (63 reviews)
"This property is beautiful and everything is thought of for the guests. The hosts were amazing. It is close to wonderful state parks. My family had a great time. I would stay here again!"
United States
Jennifer D.
The price is AED 621
AED 763 total
includes taxes & fees
26 Oct - 27 Oct
The Sutton House 2 blocks from Main Street & Courthouse Square
A house with a porch, a staircase, and a door.

12. "The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (11 reviews)
"Thank you again for a great stay! This is a perfect little cabin !"
United States
Angela S.
The price is AED 444
AED 886 total
includes taxes & fees
11 Oct - 12 Oct
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
A wooden deck with two Adirondack chairs and a hammock.

13. Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
United States
Chris
The price is AED 726
AED 1,139 total
includes taxes & fees
12 Oct - 13 Oct
Tiny Houses of French Village
A campfire surrounded by benches in a wooded park area.

14. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
10.0 out of 10, Exceptional, (1 review)
"Very cozy"
United States
Shea E.
The price is AED 452
AED 890 total
includes taxes & fees
3 Nov - 4 Nov
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
A fire pit table with four Adirondack chairs around it, set on a concrete patio with a grassy field in the background.

15. Golf Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen

Golf Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen
Farmington
10.0 out of 10, Exceptional, (34 reviews)
"Awesome place to stay and great host!"
United States
Mike M.
The price is AED 533
AED 1,355 total
includes taxes & fees
4 Nov - 5 Nov
Golf Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen
A modern kitchen with white cabinets, a stainless steel microwave, and a coffee bar with stools.

16. Charming 1860s Renovated Home

Charming 1860s Renovated Home
Ironton
8.0 out of 10, Very good, (20 reviews)
"Had a great stay"
United States
Kevin S.
Charming 1860s Renovated Home
A living room with a TV, a fireplace, a sofa, and wall art.

17. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
11 Oct - 12 Oct
Little Blue Cottage on Spanish
A living room with a brick fireplace, a sofa, a coffee table, and a television mounted on the wall.

18. Serenity in Town 2-bedroom, 4 beds house in charming Farmington

Serenity in Town 2-bedroom, 4 beds house in charming Farmington
Farmington
10.0 out of 10, Exceptional, (4 reviews)
"Really enjoyed our stay. It was clean, close to town and shopping. Not to far from St Genevieve where we went to an event. I would stay here again."
United States
Beth M.
The price is AED 599
AED 1,121 total
includes taxes & fees
20 Oct - 21 Oct
Serenity in Town 2-bedroom, 4 beds house in charming Farmington
A house with a front porch decorated with hay bales, a scarecrow, and pumpkins.

19. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
9.0 out of 10, Wonderful, (17 reviews)
"Very clean, well stocked kitchen with necessities. We enjoyed our stay!"
United States
Melissa W.
The price is AED 422
AED 1,047 total
includes taxes & fees
17 Oct - 18 Oct
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

20. 40-Acre Poplar Bluff Nature Lovers Paradise!

40-Acre Poplar Bluff Nature Lovers Paradise!
Poplar Bluff
9.4 out of 10, Exceptional, (36 reviews)
"Beautiful location!! Had issues with the key pad - other than that all was great!"
United States
Jennie M.
The price is AED 305
AED 1,112 total
includes taxes & fees
21 Oct - 22 Oct
40-Acre Poplar Bluff Nature Lovers Paradise!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Room was clean and staff was very friendly"
Troy 1-night trip
Posted 15 hours ago
Pear Tree Inn Cape Girardeau West

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