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Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Southeast Missouri vacation homes

A modern kitchen with grey cabinets, a black refrigerator, and a microwave.

1. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (31 reviews)
"Very nice stay we enjoyed would definitely stay again"
United States
Ben C.
The price is AED 511
AED 922 total
includes taxes & fees
1 Nov - 2 Nov
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
A kitchen with white cabinets, a wooden dining table, a built-in stove, and a trash can.

2. Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.8 out of 10, Exceptional, (37 reviews)
"Super cute house in a great location."
United States
Theresa
The price is AED 397
AED 935 total
includes taxes & fees
1 Nov - 2 Nov
Cozy Three bedroom home in Central Farmington
A covered outdoor seating area with a table and chairs, string lights, and a gravel ground.

3. Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (47 reviews)
"This place is a gem! Country setting, but only a few minutes from shops and restaurants. New and extremely well stocked. Perfect for a couple looking to get away. Host is super responsive and accommodating! Will definitely be back."
United States
Philip
The price is AED 459
AED 509 total
includes taxes & fees
1 Nov - 2 Nov
Clifford's Country Cottage
A bedroom with a bed, a bench, and a ceiling fan.

4. AV Bungalows #9B

AV Bungalows #9B
Arcadia
10.0 out of 10, Exceptional, (2 reviews)
"My husband and I really enjoyed our stay! The Bungalow was perfect for us and will definitely be staying again when we come back to Arcadia!!"
United States
Theresa R.
The price is AED 498
AED 584 total
includes taxes & fees
10 Nov - 11 Nov
AV Bungalows #9B
A compact living space with a sofa, dining table, kitchen area, and a ceiling fan.

5. Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.4 out of 10, Exceptional, (11 reviews)
"Host was very helpful and accommodating! Very cute and small house, perfect for our weekend stay! "
United States
Amber P.
The price is AED 261
AED 531 total
includes taxes & fees
2 Nov - 3 Nov
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
A modern kitchen with white cabinets, a stainless steel microwave, and a coffee bar with stools.

6. Charming 1860s Renovated Home

Charming 1860s Renovated Home
Ironton
8.0 out of 10, Very good, (20 reviews)
"Had a great stay"
United States
Kevin S.
The price is AED 505
AED 942 total
includes taxes & fees
1 Nov - 2 Nov
Charming 1860s Renovated Home
A wooden deck with outdoor seating and a fire pit, surrounded by trees.

7. The Stonehouse - Private Hot Tub - Sleeps 5

The Stonehouse - Private Hot Tub - Sleeps 5
Fredericktown
9.8 out of 10, Exceptional, (8 reviews)
"The Stonehouse was every bit as cute and comfortable as expected! We enjoyed staying here as a great base for hiking in the area. The tiny town is a neat complex of different types of place to stay plus the Station coffee house was great to have in walking distance. "
United States
Beth A.
The price is AED 521
AED 886 total
includes taxes & fees
30 Nov - 1 Dec
The Stonehouse - Private Hot Tub - Sleeps 5
A wooden deck with steps leading to a house, surrounded by trees.

8. Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (101 reviews)
"Gorgeous property, wonderful hosts. Would love to visit again "
United States
Anonymous traveler
The price is AED 386
AED 481 total
includes taxes & fees
2 Nov - 3 Nov
Get Away Acres 1/2 mile off highway 60 extra sanitized
A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

9. Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
Hunting / Fishing Cabin at Lake Wappapello
A house with a porch, a staircase, and a door.

10. "The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (11 reviews)
"Beautiful place. Felt like home."
United States
Chris T.
The price is AED 511
AED 962 total
includes taxes & fees
1 Nov - 2 Nov
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
A two-story house with a balcony, surrounded by trees and a well-maintained lawn.

11. Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (53 reviews)
"Great location. We loved watching the chickens."
United States
Emily N.
The price is AED 474
AED 915 total
includes taxes & fees
1 Nov - 2 Nov
Your home away from home in downtown, historic Farmington!
A window with a vase of flowers and a book on a wooden table.

12. The Sutton House 2 blocks from Main Street & Courthouse Square

The Sutton House 2 blocks from Main Street & Courthouse Square
Ironton
10.0 out of 10, Exceptional, (65 reviews)
"Great spot just a couple of blocks from the town square. Nice and quiet."
United States
Craig H.
The price is AED 621
AED 759 total
includes taxes & fees
10 Nov - 11 Nov
The Sutton House 2 blocks from Main Street & Courthouse Square
A living room with a TV, a fireplace, a sofa, and wall art.

13. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
1 Nov - 2 Nov
Little Blue Cottage on Spanish
A wooden deck with two Adirondack chairs and a hammock.

14. Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
United States
Chris
The price is AED 817
AED 1,250 total
includes taxes & fees
2 Nov - 3 Nov
Tiny Houses of French Village
Property grounds

15. Group Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen

Group Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen
Farmington
10.0 out of 10, Exceptional, (34 reviews)
"Awesome place to stay and great host!"
United States
Mike M.
The price is AED 384
AED 1,174 total
includes taxes & fees
1 Nov - 2 Nov
Group Getaway Sleeps 8 • King Bed • Arcade • Bumper Pool • Full Kitchen
A modern kitchen with wooden cabinets, a stainless steel refrigerator, an oven, and a dishwasher. There is a dining table with chairs and a small rug on the floor.

16. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Poplar Bluff
9.0 out of 10, Wonderful, (18 reviews)
"Very clean, well stocked kitchen with necessities. We enjoyed our stay!"
United States
Melissa W.
The price is AED 422
AED 1,047 total
includes taxes & fees
1 Nov - 2 Nov
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, an oven, and a granite countertop.

17. RUSTIC RETREAT Cozy 2 Bed 1.5 Bath Home, in Rural Farmington, Wooded Outdoor.

RUSTIC RETREAT Cozy 2 Bed 1.5 Bath Home, in Rural Farmington, Wooded Outdoor.
Farmington
9.4 out of 10, Exceptional, (11 reviews)
"An absolutely amazing place to be!"
United States
danny s.
The price is AED 584
AED 672 total
includes taxes & fees
1 Nov - 2 Nov
RUSTIC RETREAT Cozy 2 Bed 1.5 Bath Home, in Rural Farmington, Wooded Outdoor.
A living room with a brick fireplace, a sofa, a coffee table, and a television mounted on the wall.

18. Serenity in Town 2-bedroom, 4 beds house in charming Farmington

Serenity in Town 2-bedroom, 4 beds house in charming Farmington
Farmington
10.0 out of 10, Exceptional, (4 reviews)
"Really enjoyed our stay. It was clean, close to town and shopping. Not to far from St Genevieve where we went to an event. I would stay here again."
United States
Beth M.
The price is AED 536
AED 1,049 total
includes taxes & fees
2 Nov - 3 Nov
Serenity in Town 2-bedroom, 4 beds house in charming Farmington
A two-story cylindrical building with a covered porch and a welcoming sign.

19. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (159 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
The price is AED 878
AED 1,360 total
includes taxes & fees
1 Nov - 2 Nov
Silo Farm Haus- located in the heart of wine country!
A small, single-story building with a porch, red chairs, and a fan.

20. 5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana

5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
New Offenburg
10.0 out of 10, Exceptional, (2 reviews)
"This was one of the best places I’ve ever stayed. Owner thought of everything and it was so comfortable. The space was perfect, extra blankets, both types of coffee makers, firewood on site. This is a very new property and everything was immaculate and clean. Was easy to navigate check-in and house was so cute! Would definitely recommend to anyone heading to St Gen or any of surrounding areas."
United States
Carole J.
The price is AED 698
AED 1,019 total
includes taxes & fees
1 Nov - 2 Nov
5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

10/10 Excellent
"Buffet was excellent, great selections"
Adam 1-night trip
Posted 7 hours ago
Comfort Inn Festus - St Louis South

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