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Search Vacation Homes in Southeast Missouri

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Compare 141 Vacation Homes in Southeast Missouri with updated reviews, rates, and availability.

The Ole Tin Can
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
10.0 out of 10, Exceptional, (68)
"I love staying here. It is so clean and comfortable. I loved waking up in the morning and having my coffee on the front porch soaking in the beautiful natural world. It far enough away from town to enjoy the quiet but close enough to grab delicious food for meals. I’ll always stay here when visiting Eminence."
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
Living Room
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (7)
"Very nice little house and good stay"
The price is AED 441
AED 957 total
includes taxes & fees
30 May - 31 May
Cozy Three bedroom home in Central Farmington
Private kitchen
Quiet, Cozy Cabin!
8.6 out of 10, Excellent, (4)
"Cabin was exactly as pictured. Very comfortable for a short to medium stay, house was extremely clean when we got there. Owner was very quick to respond and was able to make arrangements for us. Will be coming back!"
The price is AED 356
AED 691 total
includes taxes & fees
27 May - 28 May
Quiet, Cozy Cabin!
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Living area
Cozy town house - 3 Queen beds
10.0 out of 10, Exceptional, (2)
"We only used our stay to sleep and get ready. We gathered with our family so we only needed a place to stay. We would stay again if we were back in the area. The host were available when we called and they are very nice Hosts."
The price is AED 327
AED 627 total
includes taxes & fees
27 May - 28 May
Cozy town house - 3 Queen beds
Outdoor dining
RIVER FRONT HOUSE
9.8 out of 10, Exceptional, (23)
"Amazing place would love to go there again."
RIVER FRONT HOUSE
Exterior
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is AED 551
AED 896 total
includes taxes & fees
28 May - 29 May
Serenity South -- Gardens, River-Views, and Refreshing Space
Exterior
Beautiful historical two story stone farmhouse
10.0 out of 10, Exceptional, (42)
"This place was absolutely gorgeous and so peaceful. Highly recommend it. It was so cool staying someplace with so much history."
The price is AED 992
AED 1,443 total
includes taxes & fees
27 May - 28 May
Beautiful historical two story stone farmhouse
Exterior
Your home away from home in downtown, historic Farmington!
10.0 out of 10, Exceptional, (5)
"Have rented 2 prior locations and this was the best. Clean pleasant great location and was very surprised to see soap provided as well as coffee ...and so much more. I very much liked we had 2 separate bedrooms with doors! and 2 bathrooms. I was able to wash clothes and it was quiet! Great walking location. I would have loved to have stayed a week. Bed was very comfy."
The price is AED 400
AED 757 total
includes taxes & fees
29 May - 30 May
Your home away from home in downtown, historic Farmington!
The 1801 House
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
10.0 out of 10, Exceptional, (97)
"Our visit was short and we didn’t get to spend much time in the home and town, came for our grandson’s wedding. But the time we had in the house and town was amazing. Thank you for sharing your home with us. It added to the beautiful occasion we came to the area for ☺️"
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
"Little Brick House on Main (1865)”
10.0 out of 10, Exceptional, (26)
"We took an impromptu overnight from St. Louis. Wonderful place in a nice area. Lots of places to see."
The price is AED 485
AED 632 total
includes taxes & fees
24 May - 25 May
"Little Brick House on Main (1865)”
Welcome to Skyline Drive Getaway
Guests enjoy their own one bedroom apartment in the Ozarks
10.0 out of 10, Exceptional, (54)
"Everything was great "
Guests enjoy their own one bedroom apartment in the Ozarks
Pond area with dock, pedal boat, and paddle board.
Rustic Lodge for 14 near Current River on private 35 acres
10.0 out of 10, Exceptional, (12)
"Nine of us women cousins thoroughly enjoyed our three night stay. Lodge and grounds are beautiful. Everything we needed was right there. Only suggestion would be to include the pool fee in the daily rate and it be available all day. Thanks for a great time."
Rustic Lodge for 14 near Current River on private 35 acres
Pool
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
10.0 out of 10, Exceptional, (51)
"We came with our whole family for a family vacation. We definitely enjoyed our time there even with three toddlers. The property is well cleaned and taken care of. My toddler’s favorite things to do during our stay was saying hi to the pony every morning, swimming, and playing with the neighbor dogs outside."
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
Poplar Bluff Vacation Rental | 2BR | 2BA | 2,558 Sq Ft | Access Only By Stairs
40-Acre Poplar Bluff Nature Lovers Paradise!
9.4 out of 10, Exceptional, (22)
"Had everything we was wanting on our visit. And more. Very comfortable and accommodating. If we are back that way again will definitely try it again. Thanks."
40-Acre Poplar Bluff Nature Lovers Paradise!
Bathroom
Newly renovated early 1900’s farmhouse
10.0 out of 10, Exceptional, (8)
"This house was a cozy, comfortable place to stay. Although it sits on a road that's busier than what I'm use to, I slept better than I had in a long time. I have nothing but good things to say about it."
The price is AED 584
AED 923 total
includes taxes & fees
28 May - 29 May
Newly renovated early 1900’s farmhouse
Front entance
Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
10.0 out of 10, Exceptional, (62)
"We held our family Christmas here. 13 people, 7 adults and 6 children. We spent 6 days here. People played pool, ping pong, games, swam and we grilled outside. This house has everything you would in your own home! One day I hosted our huge family gathering of 40+people, plenty of room, it was nice outside and inside and once again everything is provided at the house. I would recommend this house to everyone. Beautiful home. I will rent this house again. Julie"
Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
New Summer 2018
Gabouri Place ~ Completely Renovated Victorian in Ste. Genevieve's Historic Dist
10.0 out of 10, Exceptional, (148)
"Would stay again."
Gabouri Place ~ Completely Renovated Victorian in Ste. Genevieve's Historic Dist
Property grounds
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
8.6 out of 10, Excellent, (15)
"The old house was charming. It could benefit from a really good, deep clean. The bathrooms and beds/linens were very clean and the kitchen was functional. We didn't use the outdoor area but it was nice and well suited to a comfortable place to hang out on a nice day. The town has food and necessity shopping available and easily accessible. Overall we were pleased with our overnight stay. "
The price is AED 327
AED 712 total
includes taxes & fees
27 May - 28 May
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
Exterior
Gorgeous large rental home in Lesterville MO just minutes from Blackwater River.
10.0 out of 10, Exceptional, (4)
"We cane for the total eclipse and couldn’t have picked a better place. The community is friendly, the parks are fun and the house was the oerfect balance of old and new. The beds are comfortable and the firepit makes for great storytelling and s’mores. Highly recommend."
The price is AED 1,102
AED 1,862 total
includes taxes & fees
27 May - 28 May
Gorgeous large rental home in Lesterville MO just minutes from Blackwater River.
Property grounds
Private lake, beach & hot tub, romantic getaway or family vaca
10.0 out of 10, Exceptional, (13)
"We enjoyed our stay and were able to have a relaxing getaway."
Private lake, beach & hot tub, romantic getaway or family vaca
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Southeast Missouri

Exterior
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
3.5 star property
9.4 out of 10, Exceptional, (126)
"When we walked in the lodge it was spotless. Very homey and clean. The staff was so kind. We will definitely be back."
The price is AED 657
AED 732 total
includes taxes & fees
9 Jun - 10 Jun
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Exterior
Secluded Ozarks Tiny House cabin in Eminence, MO
10.0 out of 10, Exceptional, (78)
"My husband, young children (6 and 4), and I enjoyed our stay. The cabin was cute and clean. Great place to stay."
Secluded Ozarks Tiny House cabin in Eminence, MO
The Ole Tin Can
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
10.0 out of 10, Exceptional, (68)
"I love staying here. It is so clean and comfortable. I loved waking up in the morning and having my coffee on the front porch soaking in the beautiful natural world. It far enough away from town to enjoy the quiet but close enough to grab delicious food for meals. I’ll always stay here when visiting Eminence."
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent reviews of Southeast Missouri hotels
Expedia verified reviews