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Compare 141 Vacation Homes in Southeast Missouri with updated reviews, rates, and availability.
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
10.0 out of 10, Exceptional, (68)
Cozy Three bedroom home in Central Farmington
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (7)
The price is AED 441
AED 957 total
includes taxes & fees
30 May - 31 May
Quiet, Cozy Cabin!
Quiet, Cozy Cabin!
8.6 out of 10, Excellent, (4)
The price is AED 356
AED 691 total
includes taxes & fees
27 May - 28 May
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Cozy town house - 3 Queen beds
Cozy town house - 3 Queen beds
10.0 out of 10, Exceptional, (2)
The price is AED 327
AED 627 total
includes taxes & fees
27 May - 28 May
RIVER FRONT HOUSE
RIVER FRONT HOUSE
9.8 out of 10, Exceptional, (23)
Serenity South -- Gardens, River-Views, and Refreshing Space
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
The price is AED 551
AED 896 total
includes taxes & fees
28 May - 29 May
Beautiful historical two story stone farmhouse
Beautiful historical two story stone farmhouse
10.0 out of 10, Exceptional, (42)
The price is AED 992
AED 1,443 total
includes taxes & fees
27 May - 28 May
Your home away from home in downtown, historic Farmington!
Your home away from home in downtown, historic Farmington!
10.0 out of 10, Exceptional, (5)
The price is AED 400
AED 757 total
includes taxes & fees
29 May - 30 May
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
The 1801 House: A beautiful historic home in the Ste Genevieve Historic District
10.0 out of 10, Exceptional, (97)
"Little Brick House on Main (1865)”
"Little Brick House on Main (1865)”
10.0 out of 10, Exceptional, (26)
The price is AED 485
AED 632 total
includes taxes & fees
24 May - 25 May
Guests enjoy their own one bedroom apartment in the Ozarks
Guests enjoy their own one bedroom apartment in the Ozarks
10.0 out of 10, Exceptional, (54)
Rustic Lodge for 14 near Current River on private 35 acres
Rustic Lodge for 14 near Current River on private 35 acres
10.0 out of 10, Exceptional, (12)
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
Bluebird Meadows with In-ground Pool and Hot Tub! 125 ACRES TO EXPLORE
10.0 out of 10, Exceptional, (51)
40-Acre Poplar Bluff Nature Lovers Paradise!
40-Acre Poplar Bluff Nature Lovers Paradise!
9.4 out of 10, Exceptional, (22)
Newly renovated early 1900’s farmhouse
Newly renovated early 1900’s farmhouse
10.0 out of 10, Exceptional, (8)
The price is AED 584
AED 923 total
includes taxes & fees
28 May - 29 May
Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
10.0 out of 10, Exceptional, (62)
Gabouri Place ~ Completely Renovated Victorian in Ste. Genevieve's Historic Dist
Gabouri Place ~ Completely Renovated Victorian in Ste. Genevieve's Historic Dist
10.0 out of 10, Exceptional, (148)
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
8.6 out of 10, Excellent, (15)
The price is AED 327
AED 712 total
includes taxes & fees
27 May - 28 May
Gorgeous large rental home in Lesterville MO just minutes from Blackwater River.
Gorgeous large rental home in Lesterville MO just minutes from Blackwater River.
10.0 out of 10, Exceptional, (4)
The price is AED 1,102
AED 1,862 total
includes taxes & fees
27 May - 28 May
Private lake, beach & hot tub, romantic getaway or family vaca
Private lake, beach & hot tub, romantic getaway or family vaca
10.0 out of 10, Exceptional, (13)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other property types in Southeast Missouri
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
9.4 out of 10, Exceptional, (126)
The price is AED 657
AED 732 total
includes taxes & fees
9 Jun - 10 Jun
Secluded Ozarks Tiny House cabin in Eminence, MO
Secluded Ozarks Tiny House cabin in Eminence, MO
10.0 out of 10, Exceptional, (78)
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
Unique cabins in the woods<br>Not friendly for Street Bikes. Beautifulin FALL!
10.0 out of 10, Exceptional, (68)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southeast Missouri hotelsExpedia verified reviews
5/5 Excellent
"Great value and super quiet. "
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 13 hours ago
Popular Destinations
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More Accommodation Types in Southeast Missouri
- Cabin Rentals in Southeast Missouri (78)
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- Cottages in Southeast Missouri (35)
- Motels in Southeast Missouri (23)
- Farmstay in Southeast Missouri (14)
- Resorts in Southeast Missouri (12)
- Lodges in Southeast Missouri (10)
- Condo Rentals in Southeast Missouri (4)
- RV Parks in Southeast Missouri (3)
- Aparthotels in Southeast Missouri (2)
- B&B in Southeast Missouri (1)
- Villas in Southeast Missouri (1)
- Hotels (570)