A wooden bench in a forest with a natural backdrop of trees and foliage.

Find Luxury Hotels in Southeastern Indiana

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana Luxury Hotels

Tonight
2 Sep - 3 Sep
Tomorrow
3 Sep - 4 Sep
This weekend
4 Sep - 6 Sep
Next weekend
11 Sep - 13 Sep

Our top choices for Southeastern Indiana luxury hotels

1. The Grady

The Grady
Downtown Louisville
AED 686
AED 807 total
includes taxes & fees
4 Sep - 5 Sep
The Grady

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
AED 837
AED 985 total
includes taxes & fees
13 Sep - 14 Sep
Hotel Distil, Autograph Collection

3. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
AED 732
AED 861 total
includes taxes & fees
3 Sep - 4 Sep
Omni Louisville Hotel

4. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
AED 730
AED 859 total
includes taxes & fees
13 Sep - 14 Sep
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

5. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.
AED 657
AED 792 total
includes taxes & fees
7 Sep - 8 Sep
21c Museum Hotel Louisville

6. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Upscale riverside hotel features panoramic views, spa services, and gourmet dining in downtown Louisville.
AED 585
AED 688 total
includes taxes & fees
3 Sep - 4 Sep
Galt House Hotel Trademark Collection by Wyndham

7. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
AED 629
AED 740 total
includes taxes & fees
7 Sep - 8 Sep
Louisville Marriott Downtown

8. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
  • Upscale Louisville hotel features concierge, gourmet dining, and spacious suites with living areas.
AED 486
AED 572 total
includes taxes & fees
9 Sep - 10 Sep
Embassy Suites Louisville Downtown

9. The Brown Hotel

The Brown Hotel
Downtown Louisville
  • Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.
AED 493
AED 580 total
includes taxes & fees
3 Sep - 4 Sep
The Brown Hotel

10. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
  • Historic elegance meets modern luxury downtown, with pillowtop beds, designer toiletries, and 24-hour service.
AED 558
AED 656 total
includes taxes & fees
6 Sep - 7 Sep
Seelbach Hilton Louisville Downtown
View all properties

Top Southeastern Indiana Hotel Reviews