The Best Luxury Hotels in Southeastern Indiana from AED 326 in 2026 | Expedia

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Check availability on Southeastern Indiana Luxury Hotels

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16 Oct - 18 Oct

Our top choices for Southeastern Indiana luxury hotels

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A steam fountain in a brick alleyway.

1. 21c Museum Hotel Louisville

Downtown Louisville

Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.

AED 731

AED 878 total

includes taxes & fees

25 Oct - 26 Oct

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand lobby with ornate ceiling, large windows, and classic furniture.

2. The Brown Hotel

Downtown Louisville

Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.

AED 493

AED 580 total

includes taxes & fees

28 Oct - 29 Oct

A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

A long table set with white tablecloths, gold chargers, and clear glassware.

A covered porch with a brick wall, a wooden door, and a hanging light fixture.

A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

3. The Pepin Mansion Historic B&B

New Albany

AED 288

AED 326 total

includes taxes & fees

12 Oct - 13 Oct

A bedroom with a large bed, a wooden floor, a white door, and a painting on the wall.

A cozy living room with a staircase, a sofa, a patterned rug, and a small table with a lamp.

A modern kitchen with a central island, wooden bar stools, a black refrigerator, and white cabinetry.

A dining area with a piano, a large woven pendant light, and a patterned rug.

4. Eclectic & Unique Historic Home

New Albany

AED 588

AED 1,710 total

includes taxes & fees

12 Oct - 13 Oct

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

5. Louisville Bourbon Inn

Old Louisville

Luxurious bourbon country retreat offers elegant rooms with Egyptian cotton sheets and champagne service just minutes from downtown.

AED 1,025

AED 1,189 total

includes taxes & fees

11 Oct - 12 Oct

A wooden deck with a table, chairs, and a lantern.

A large, historic house with a green roof, multiple chimneys, and a prominent front porch.

A cozy porch area with wicker furniture, a ceiling fan, string lights, and a welcome sign.

A grand staircase with dark wood railings and a chandelier.

6. Inn at Woodhaven

St. Matthews

AED 920

AED 1,068 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Top Southeastern Indiana Hotel Reviews

Hyatt Select Louisville North

Hyatt Select Louisville North

8/10 Good

"This was a good place to stay over night. Phone didnt work. But the many outlets were convenient. Good location, good dark out curtains. Peaceful area."

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

10/10 Excellent

"Rooms were really clean"