The Best Business Hotels in Southern Minnesota, MN from AED 281 in 2026 | Expedia

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Check availability on Southern Minnesota Business Hotels

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16 Oct - 18 Oct

Our top choices for Southern Minnesota business-friendly hotels

A spacious interior with a herringbone wood floor, a kitchen area with granite countertops, and a staircase with patterned carpet.

A hotel room with a large bed, two bedside tables with lamps, a wooden door, and three framed pictures on the wall.

The entrance to AmericInn by Wyndham, featuring a stone facade, a blue sign with stars, and a number 240.

A buffet setup with multiple serving stations, a chalkboard with ice cream popsicle decorations, and a coffee station with various beverage dispensers.

1. AmericInn by Wyndham Mankato Event Center

Mankato

United States

richard

AED 290

AED 322 total

includes taxes & fees

11 Oct - 12 Oct

A courtyard with rows of white chairs and tables, a pool, and a Marriott hotel building in the background.

A modern bar area with a curved white countertop, bar stools, and a variety of beverages in glass cases.

A modern bar area with a central island, bar stools, and a variety of beverages.

A Courtyard by Marriott hotel with outdoor seating, a water feature, and a well-maintained garden.

2. Courtyard Mankato Marriott

Mankato

United States

Corey

AED 360

AED 400 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a curved design, surrounded by palm trees and a white pool ladder.

A hotel room with a large bed, a desk, a chair, and a view of the outdoors through the window.

A modern hotel with a prominent neon sign, multiple floors, and a well-maintained lawn area.

A modern interior with a fireplace, a green armchair, and a patterned rug.

3. Treasure Island Resort & Casino

Welch

United States

Bill

AED 281

AED 354 total

includes taxes & fees

12 Oct - 13 Oct

A Comfort Inn & Suites building with a covered entrance, numbered 2000, and a parking lot with cars.

A barn with a metal roof and a fenced area with a pond and rocks.

A modern hotel lobby with blue armchairs, round tables, and a patterned carpet.

A room with a large sliding glass door leading to an outdoor patio with tables and chairs, potted plants, and a view of trees and grass.

4. Comfort Inn & Suites North Mankato

Mankato

United States

Joshua

AED 344

AED 381 total

includes taxes & fees

28 Oct - 29 Oct

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

5. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

United States

howard

AED 465

AED 536 total

includes taxes & fees

24 Oct - 25 Oct

A hotel with outdoor seating and a fire pit.

An indoor swimming pool with lounge chairs and a tiled floor.

A bar area with a long counter, multiple stools, and framed pictures on the wall.

A building with a sign reading "Legends Bar & Grill" above a stone facade.

6. Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN

Mankato

United States

Deborah

AED 372

AED 412 total

includes taxes & fees

28 Oct - 29 Oct

A modern hotel lobby with a dining area, seating arrangements, and a stone fireplace.

An outdoor patio area with stone walls, a stone fireplace, and multiple tables and chairs.

A hotel with a modern design, featuring a stone facade and a covered entrance.

Reception

7. Fairfield Inn & Suites by Marriott Winona

Winona

United States

Stephanie

AED 493

AED 550 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor pool area with multiple levels, a hot tub, and a seating area with tables and chairs.

A hotel room with a bed, a sofa, an ottoman, a nightstand, a lamp, and a framed picture on the wall.

A modern living room with a fireplace, green armchairs, and a large sofa.

A reception area with two counters, a green wall with branch designs, and a tiled floor.

8. Best Western Plus New Ulm

New Ulm

United States

krista

AED 437

AED 485 total

includes taxes & fees

22 Oct - 23 Oct

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Top Southern Minnesota Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"Hot tub jets were not functioning. We sat in the hot tub without water moving."

Brentwood Inn & Suites

Brentwood Inn & Suites

8/10 Good

"Breakfast was okay. Expected eggs of some sort but no hot food. Very clean and well maintained property"

Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

8/10 Good

"The food at the bar was good Breakfast was good for a hotel Breakfast"

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Great location. Great accommodations. Highly recommended."

AmericInn by Wyndham Mankato Event Center

AmericInn by Wyndham Mankato Event Center

10/10 Excellent

"My stay was fine"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Excellent location. Great shuttle service to mayo gonna. No working wifi in my room but other than that was fine."

The Plaza Hotel & Suites Winona

The Plaza Hotel & Suites Winona

8/10 Good

"The shower curtain had mold on the bottom. The bathroom needed a good wipe down around the bottom of the walls and door . The two chairs at the table were scraping the paint off the wall. But overall I would stay again ."

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