Search Vacation Homes in Southern Minnesota

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
12 Sep - 14 Sep
In two weeks
19 Sep - 21 Sep
In one month
3 Oct - 5 Oct
In two months
31 Oct - 2 Nov

Vacation Homes in Southern Minnesota

Our top choices for Southern Minnesota vacation homes

ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!
Property grounds

ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!

9.6 out of 10, Exceptional, (75)
"Convient every thing we needed was available, appreciate the snacks owners very nice, games and activities available really appreciated everything "
ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!
Holiday Haus Zwei
Smart TV, books

Holiday Haus Zwei

10.0 out of 10, Exceptional, (82)
"The house was perfect for our need of a place to stay for the family for a wedding."
Holiday Haus Zwei
The Hen House Retreat - A Comfortable Place to Roost
Exterior detail

The Hen House Retreat - A Comfortable Place to Roost

9.6 out of 10, Exceptional, (84)
"We enjoyed taking it easy watching some movies and crafting together for the weekend."
The price is AED 595
AED 730 total
includes taxes & fees
3 Sep - 4 Sep
The Hen House Retreat - A Comfortable Place to Roost
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Fridge, microwave, oven, stovetop

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

10.0 out of 10, Exceptional, (57)
"This was the perfect place for us to stay, everything was comfortable and had just what we needed. Not far from Mayo Clinic. "
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
*THE BLACK SHEEP* - Modern, Unique & Clean - BY MSU
Fridge, microwave, oven, stovetop

*THE BLACK SHEEP* - Modern, Unique & Clean - BY MSU

3.0 star property
10.0 out of 10, Exceptional, (20)
"This VRBO was such a great house to stay in. Jenna was so helpful with questions and our needs. Everything was furnished. Great stay. I highly recommend this home. "
The price is AED 547
AED 969 total
includes taxes & fees
11 Sep - 12 Sep
*THE BLACK SHEEP* - Modern, Unique & Clean - BY MSU
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Fridge, microwave, oven, stovetop

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (34)
"This home is Central to the Mayo clinic The home is very nice and clean with everything you could possibly need for your stay. We would be back in a few months and definitely be staying here"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Log Inn on Madison Lake. Multi generation. Corporate retreat for team building
Dining

Log Inn on Madison Lake. Multi generation. Corporate retreat for team building

10.0 out of 10, Exceptional, (115)
"We had a great experience."
Log Inn on Madison Lake. Multi generation. Corporate retreat for team building
Fantastic Large Home Right On Beautiful Lake Pepin!
Property grounds

Fantastic Large Home Right On Beautiful Lake Pepin!

10.0 out of 10, Exceptional, (243)
"Great location, roomy house with all amenities needed. "
Fantastic Large Home Right On Beautiful Lake Pepin!
Fountain City Loft, hot tub, river views
Fridge, microwave, oven, stovetop

Fountain City Loft, hot tub, river views

10.0 out of 10, Exceptional, (25)
"We enjoyed the accommodations. Would highly recommend."
Fountain City Loft, hot tub, river views
Cozy 4 bedroom relax atmosphere enjoy beauty of bluff country driftless region
Smart TV, DVD player, books

Cozy 4 bedroom relax atmosphere enjoy beauty of bluff country driftless region

9.6 out of 10, Exceptional, (28)
"We absolutely loved this home and area! Very clean house and well-stocked kitchen which made making our meals easy. Would definitely stay again!"
Cozy 4 bedroom relax atmosphere enjoy beauty of bluff country driftless region
NEW Build Home with Outdoor Oasis | Game Room | Bunkroom
Terrace/patio

NEW Build Home with Outdoor Oasis | Game Room | Bunkroom

10.0 out of 10, Exceptional, (4)
"We had a great stay and experience! The property offered fun and relaxation for all ages in our group. We would highly recommend staying here!"
The price is AED 1,207
AED 1,810 total
includes taxes & fees
3 Sep - 4 Sep
NEW Build Home with Outdoor Oasis | Game Room | Bunkroom
Victorian era Mississippi riverview retreat.
Property grounds

Victorian era Mississippi riverview retreat.

9.8 out of 10, Exceptional, (30)
"Property was clean, comfortable, and just what we were looking for."
Victorian era Mississippi riverview retreat.
Charming rambler in lovely Stockholm with a beautiful lake view, A/C, and WiFi.
Fridge, oven, stovetop, coffee/tea maker

Charming rambler in lovely Stockholm with a beautiful lake view, A/C, and WiFi.

7.6 out of 10, Good, (5)
The price is AED 680
AED 814 total
includes taxes & fees
24 Sep - 25 Sep
Charming rambler in lovely Stockholm with a beautiful lake view, A/C, and WiFi.
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (93)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Exterior

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

10.0 out of 10, Exceptional, (13)
"Clean property, affordable price, good experience all around!"
The price is AED 551
AED 676 total
includes taxes & fees
3 Sep - 4 Sep
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Family friendly in the peaceful heart of town
Interior

Family friendly in the peaceful heart of town

10.0 out of 10, Exceptional, (100)
"Stayed for a short weekend in Winona and was perfect. Great location and exactly as advertised."
Family friendly in the peaceful heart of town
"Walden Pond" Adventure Amidst 44 Private Acres
Interior

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (134)
"Beautiful accommodations, great communication, wonderful hiking, campfires and smores! Our third visit and we love it every time! "
"Walden Pond" Adventure Amidst 44 Private Acres
Welcome to Serenity - Spacious 4-bedroom townhome in Mankato minutes from MSU
Private kitchen

Welcome to Serenity - Spacious 4-bedroom townhome in Mankato minutes from MSU

10.0 out of 10, Exceptional, (12)
"This was a nice stay. The property was very clean and spacious "
Welcome to Serenity - Spacious 4-bedroom townhome in Mankato minutes from MSU
Comfy Rustic Retreat 2 blocks from Mayo Hospital and Bethany College.
Fridge, microwave, oven, stovetop

Comfy Rustic Retreat 2 blocks from Mayo Hospital and Bethany College.

9.8 out of 10, Exceptional, (16)
"This was the perfect place for us to stay while visiting our son who attends Mankato state. "
The price is AED 400
AED 525 total
includes taxes & fees
14 Sep - 15 Sep
Comfy Rustic Retreat 2 blocks from Mayo Hospital and Bethany College.
Lovely 2-bedroom LAKE house with AC in Fairmont
Private kitchen

Lovely 2-bedroom LAKE house with AC in Fairmont

9.4 out of 10, Exceptional, (3)
"A beautiful home, great for a small family or small group. Close to downtown. Great communication from hosts. Would definitely stay here again. "
Lovely 2-bedroom LAKE house with AC in Fairmont
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Minnesota Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia