A town nestled in a valley with a prominent building in the foreground and hills in the background.

Find Business Hotels in Southern Oregon, OR

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Oregon Business Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Southern Oregon business-friendly hotels

A spacious indoor seating area with blue sofas and round tables, large windows with a view of the beach and umbrellas, and a flat-screen TV mounted on the wall.
A hotel lobby with a wooden reception desk, a large chandelier, and a compass-themed floor design.
A deck with outdoor seating, a bar area, and a fire feature.
A hotel room with two beds, a desk, a TV, and a window with a view of the mountains.

1. Compass by Margaritaville in Medford

Compass by Margaritaville in Medford
Medford
United States
Joni
AED 559
AED 673 total
includes taxes & fees
18 Oct - 19 Oct
Compass by Margaritaville in Medford
A modern lobby with seating, a television, and artwork on the walls.
A Holiday Inn Express & Suites building with a covered entrance, multiple floors, and a parking lot.
A reception desk with a computer, a wooden partition, and a wall-mounted sign.
A modern breakfast area with a digital menu board, a coffee machine, and a yogurt dispenser.

2. Holiday Inn Express & Suites Medford by IHG

Holiday Inn Express & Suites Medford by IHG
Medford
United States
Joseph
AED 404
AED 455 total
includes taxes & fees
29 Oct - 30 Oct
Holiday Inn Express & Suites Medford by IHG
A modern building with a stone facade, a covered entrance, and a bear statue.
A large indoor swimming pool with a tiled edge, surrounded by chairs and tables, and large windows with a view of the outdoors.
A vending machine stocked with snacks and beverages, and a refrigerated display case with various food items.
A hotel room with a large bed, a chair, a desk, a television, and a door.

3. La Quinta Inn & Suites by Wyndham Grants Pass

La Quinta Inn & Suites by Wyndham Grants Pass
Grants Pass
United States
Greg
AED 377
AED 428 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Grants Pass
An outdoor patio area with a grill, wicker furniture, and a large umbrella.
A hotel named "Homewood Suites by Hilton" with a modern architectural design, featuring a prominent entrance and multiple windows.
A modern hotel room with a sofa, a small table, a TV, and a bed.
A modern hotel reception area with a marble counter, two monitors, and a minibar.

4. Homewood Suites Medford

Homewood Suites Medford
Medford
Canada
James
AED 367
AED 413 total
includes taxes & fees
31 Oct - 1 Nov
Homewood Suites Medford
A hotel entrance with outdoor seating, potted plants, and a well-lit facade.
A hotel room with a bed, a desk with a TV, a chair, and a microwave.
A hotel room with a gray sofa, a small wooden table, a framed picture on the wall, a floor lamp, and a carpeted floor.
A kitchen with a countertop displaying various food items, a refrigerator, and a coffee machine.

5. Comfort Inn & Suites Ashland

Comfort Inn & Suites Ashland
Ashland
United States
Mary Anna
AED 413
AED 419 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn & Suites Ashland
A modern hotel lobby with multiple seating areas, including round tables and chairs, and a bar area with stools.
A modern hotel with a two-story structure, a covered entrance, and a parking lot.
A hotel room with two beds, a large window with sheer curtains, a mirror, and a view of another room.
A reception area with a wooden reception desk, a modern chair, and a large window with blinds.

6. Springhill Suites By Marriott Medford Airport

Springhill Suites By Marriott Medford Airport
Medford
United States
Rijab
AED 434
AED 488 total
includes taxes & fees
25 Oct - 26 Oct
Springhill Suites By Marriott Medford Airport
A Comfort Inn sign surrounded by autumn leaves.
A hotel room with a large bed, two bedside tables, a nightstand, a mirror, and a wall-mounted lamp.
A hotel lobby with a blue sofa, red armchairs, a patterned carpet, and a reception desk.
A hotel lobby with a reception desk, seating area, and a television mounted on the wall.

7. Comfort Inn South

Comfort Inn South
Medford
United States
Anna
AED 313
AED 353 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn South
An indoor swimming pool with clear water, tiled edges, and a blue mosaic border. There are lounge chairs and potted plants near the windows.
A restaurant with wooden chairs and tables, large windows, and a dragon sculpture.
A hotel sign with the name "Straford Inn" and a stone pillar.
A lobby with leather sofas, a rug, and lamps.

8. Stratford Inn

Stratford Inn
Siskiyou-Hargadine Historic District
United States
David
AED 409
AED 456 total
includes taxes & fees
18 Oct - 19 Oct
Stratford Inn
A modern kitchen with wooden cabinets, a central island, and a black backsplash with 'EAT' written on it.
A hotel room with a flat-screen TV, a desk with a lamp, a chair, and two beds.
A reception desk with a "Welcome to the Pacific Wonderland" sign, a digital check-in station, and a "Hilton Honors" sign.
An outdoor patio area with wicker furniture and a wooden fence.

9. Hampton Inn Medford

Hampton Inn Medford
Medford
United States
Juan
AED 372
AED 418 total
includes taxes & fees
23 Oct - 24 Oct
Hampton Inn Medford
A modern hotel lobby with a reception desk, seating area, and a fireplace.
A modern hotel with a prominent American flag, a covered entrance, and a sign reading "Springhill Suites by Wyndham."
A modern hotel lobby with a curved seating area, a fireplace, and a mix of tables and chairs.
A hotel room with two beds, a bedside table with a lamp, and a large window with curtains.

10. SpringHill Suites by Marriott Medford

SpringHill Suites by Marriott Medford
Medford
Canada
Khimberly
AED 426
AED 480 total
includes taxes & fees
1 Nov - 2 Nov
SpringHill Suites by Marriott Medford
View all properties

Top Southern Oregon Hotel Reviews

Union Creek Resort

Union Creek Resort

10/10 Excellent
"Room was clean, air condition worked great. The property was amazing! I would definitely stay here again."
Karey 1-night trip
Posted 3 hours ago
Union Creek Resort
Stratford Inn

Stratford Inn

8/10 Good
"The Halloween decorations were great! Breakfast was all right, but not great. Staff was friendly and very helpful."
Kathryn 1-night trip
Posted 6 hours ago
Stratford Inn
Cerulean Hotel

Cerulean Hotel

10/10 Excellent
"Our room was very spacious with a large closet and plenty of drawer space. The kitchenette was great. We would definitely stay there again."
Chris 1-night trip
Posted 12 hours ago
Cerulean Hotel
Red Lion Inn & Suites Grants Pass

Red Lion Inn & Suites Grants Pass

8/10 Good
"This hotel was good. The breakfast was just ok."
David 4-night trip
Posted 17 hours ago
Red Lion Inn & Suites Grants Pass

Explore a world of travel with Expedia