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Check prices for these dates

In two weeks
17 Oct - 19 Oct
In two months
28 Nov - 30 Nov
In three months
26 Dec - 28 Dec
In four months
23 Jan - 25 Jan

Apartments in St. Charles

Broadway Plaza, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (162)
"Great spacious apartments for long stay. "
The price is AED 625
AED 719 total
includes taxes & fees
1 Nov - 2 Nov
Broadway Plaza, Trademark Collection by Wyndham
Penthouse Suite—Steps from Mayo Clinic Hospital
Fridge, microwave, oven, stovetop

Penthouse Suite—Steps from Mayo Clinic Hospital

10.0 out of 10, Exceptional, (13)
"Very nice to have kitchen/living area/bed and bath in different rooms. Would do again. "
Penthouse Suite—Steps from Mayo Clinic Hospital
This AMAZING river getaway is PERFECT for YOU! Private deck, grill & fire pit!
Fridge, microwave, oven, stovetop

This AMAZING river getaway is PERFECT for YOU! Private deck, grill & fire pit!

9.6 out of 10, Exceptional, (4)
"Unique location close to downtown Winona-perfect for our family gathering!"
This AMAZING river getaway is PERFECT for YOU! Private deck, grill & fire pit!
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
Fridge, microwave, oven, stovetop

Oasis Luxe Suite—Steps from Mayo Clinic Hospital

10.0 out of 10, Exceptional, (26)
"One of the best luxurious places in Rochester MN "
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
Mayo Discount Available- 2Bedroom Close to Mayo
Fridge, microwave, oven, stovetop

Mayo Discount Available- 2Bedroom Close to Mayo

8.0 out of 10, Very Good, (24)
"My sister and I needed a place to rest our heads after a celebration of life for a dear friend I slept well Thanks"
Mayo Discount Available- 2Bedroom Close to Mayo
Charming 1-bedroom condo with Mississippi River views in wonderful Fountain City
Private kitchen

Charming 1-bedroom condo with Mississippi River views in wonderful Fountain City

Charming 1-bedroom condo with Mississippi River views in wonderful Fountain City
Cozy 1-bedroom apartment in lovely Alma with WiFi, AC
Interior

Cozy 1-bedroom apartment in lovely Alma with WiFi, AC

Cozy 1-bedroom apartment in lovely Alma with WiFi, AC
Big River Inn - 3 bedroom apartment in Alma
Fridge, microwave, oven, stovetop

Big River Inn - 3 bedroom apartment in Alma

9.0 out of 10, Wonderful, (12)
"Easy check in, cute space in an historic town. We struggled with the freight train noise across the street as they ran overnight and sound the horn multiple times "
The price is AED 479
AED 1,049 total
includes taxes & fees
5 Oct - 6 Oct
Big River Inn - 3 bedroom apartment in Alma
Entire cozy Rollingstone apt in Mississippi Valley, just 10 min from Winona!
Terrace/patio

Entire cozy Rollingstone apt in Mississippi Valley, just 10 min from Winona!

10.0 out of 10, Exceptional, (21)
"“We had a wonderful stay at Hattie's Place! The house was clean, cute, and thoughtfully appointed with everything our family needed. It felt like a home away from home. We have stayed multiple times and will be coming back— highly recommended! Also a must is Bonnie Rae's next door for a delicious breakfast! "
Entire cozy Rollingstone apt in Mississippi Valley, just 10 min from Winona!
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Dining

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

10.0 out of 10, Exceptional, (6)
"This was a beautiful, clean home. The owners were also great to work with and the check in process was simple. Great for traveling alone or with family."
The price is AED 294
AED 896 total
includes taxes & fees
5 Oct - 6 Oct
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Viola Suites Apt 2 // 2 BR, Pet Friendly, Economical, Lg Yard, Near Mayo!
Property grounds

Viola Suites Apt 2 // 2 BR, Pet Friendly, Economical, Lg Yard, Near Mayo!

9.2 out of 10, Wonderful, (15)
"Great place to stay. I would stay there again if I am in the area."
Viola Suites Apt 2 // 2 BR, Pet Friendly, Economical, Lg Yard, Near Mayo!
8075-Walk to Mayo- Charming 2 bedroom Boutique Apartment
2 bedrooms, iron/ironing board, WiFi, bed sheets

8075-Walk to Mayo- Charming 2 bedroom Boutique Apartment

6.8 out of 10, (5)
"This is a very clean VRBO. The owner answers your questions within minutes. It is a small rental in size but very accommodating."
8075-Walk to Mayo- Charming 2 bedroom Boutique Apartment
8078-Walk to Mayo- 1 bed condo with full kitchen and free parking
Fridge, microwave, stovetop, coffee/tea maker

8078-Walk to Mayo- 1 bed condo with full kitchen and free parking

6.8 out of 10, (5)
"Convenient, clean, quiet, quaint."
8078-Walk to Mayo- 1 bed condo with full kitchen and free parking
Charming 2-bedroom apartment in delightful Rochester with WiFi, AC
Interior

Charming 2-bedroom apartment in delightful Rochester with WiFi, AC

10.0 out of 10, Exceptional, (1)
"Quiet, clean and in a friendly neighborhood. Staying there took some of the stress out of my Mayo Clinic visits. I always worry about my follow-up visits, but a good quiet place to stay helps me let that go."
The price is AED 349
AED 739 total
includes taxes & fees
4 Oct - 5 Oct
Charming 2-bedroom apartment in delightful Rochester with WiFi, AC
Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!
Exterior

Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

10.0 out of 10, Exceptional, (3)
"Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!"
The price is AED 482
AED 639 total
includes taxes & fees
4 Oct - 5 Oct
Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Dining

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

9.6 out of 10, Exceptional, (19)
"Great location "
The price is AED 220
AED 710 total
includes taxes & fees
7 Oct - 8 Oct
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
The Exchange 16 | Historic Bldg, Studio, Dwntwn
1 bedroom, free WiFi, bed sheets

The Exchange 16 | Historic Bldg, Studio, Dwntwn

9.6 out of 10, Exceptional, (14)
"Great place to stay with lots to do within easy walking distance."
The Exchange 16 | Historic Bldg, Studio, Dwntwn
Three-Bedroom Apartment with River View
Interior

Three-Bedroom Apartment with River View

9.2 out of 10, Wonderful, (54)
"My family was in town for a wedding. The rental was located right down town. We had many food and exploring options available to us. Diana was a wonderful host. "
Three-Bedroom Apartment with River View
8037-Walk to Mayo- Loft apt in the middle of Mayo campus
1 bedroom, iron/ironing board, WiFi, bed sheets

8037-Walk to Mayo- Loft apt in the middle of Mayo campus

2.0 out of 10, (2)
"The room wasn't ready and it wasn't anyting like they pictured we stayed in a different hotel and got our money back"
8037-Walk to Mayo- Loft apt in the middle of Mayo campus
The Gwen // Charming 2-bedroom upstairs apartment in quiet duplex
Living area

The Gwen // Charming 2-bedroom upstairs apartment in quiet duplex

2.0 star property
9.4 out of 10, Exceptional, (3)
"We loved staying at the Gwen! It’s located in a quiet neighborhood. We really appreciate the panoramic views out the windows in the cozy living room. The king beds were awesome and it’s so nice to be able to bring our pup!"
The price is AED 412
AED 1,121 total
includes taxes & fees
8 Oct - 9 Oct
The Gwen // Charming 2-bedroom upstairs apartment in quiet duplex
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"There’s a lot of street work in progress around the hotel right now; but the inconvenience is manageable. You can’t beat the price and convenience for proximity and accessibility to the Mayo Clinic. "
T 1-night trip
Posted 2 days ago
Kahler Grand Hotel

Frequently asked questions

What's it like to stay at an apartment in St. Charles?
You might have as many choices within the heart of St. Charles, but Expedia can help you locate accommodations within the larger area with similar amenities to an apartment. When you search on Expedia, you can use the filters to search for conveniences you might find in an apartment such as a kitchen. You can also filter by similar property types like vacation homes, condos, or guest houses.
Are you thinking about apartments over traditional hotel rooms?
Offering a kitchen for convenient meals, an apartment often has more space than a traditional hotel room. Apartments are a good option for solo travelers who want to live like locals, and also for families wanting the conveniences of home.
What's the best apartment I should consider for a stay in St. Charles?
Below you'll find a top apartment in the area: Broadway Plaza, Trademark Collection by Wyndham: Located in Rochester, 20.4 mi/32.9 km from the heart of St. Charles. Includes free WiFi and separate dining areas. A fitness center and onsite laundry facilities are on site.
What can I expect from the weather during my trip to St. Charles?
Weather is only one factor, but it can really affect your travel plans, especially when you're planning an extended stay in St. Charles. The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.
What should I see in St. Charles?
While you're exploring the area, Whitewater River and Root River are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you'll find Whitewater State Park and St. Mary's University of Minnesota.
What's the best way to get to and around St. Charles?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into Rochester, MN (RST-Rochester Intl.), which is located 22.6 mi (36.4 km) from the heart of the city. If you'd like to explore around the area, you may want to rent a car for your trip.