Search Vacation Homes in St. Charles

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
25 Jul - 27 Jul
In two weeks
1 Aug - 3 Aug
In one month
15 Aug - 17 Aug
In two months
12 Sep - 14 Sep

Vacation Homes in St. Charles

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Fridge, microwave, oven, stovetop

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

10.0 out of 10, Exceptional, (52)
"Great property close to everything in Rochester!"
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
Fridge, microwave, oven, stovetop

Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!

10.0 out of 10, Exceptional, (2)
"Attended Viola Gopher Count. Great place. Great location."
Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Exterior

Charming Brick Farmhouse with a Touch of Elegance. -Winona

10.0 out of 10, Exceptional, (126)
"It was very comfortable house to stay in snd share our time together. "
The price is AED 1,194
AED 1,921 total
includes taxes & fees
5 Aug - 6 Aug
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Discounted Oasis! 5 Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!

9.4 out of 10, Exceptional, (12)
"We enjoyed our stay and appreciated how easy it was to reserve and communicate with the host! Thank you so much!"
The price is AED 367
AED 1,006 total
includes taxes & fees
18 Jul - 19 Jul
Discounted Oasis! 5 Star-3 Bedroom Showstopper 4 Minutes to Mayo Clinic!
Recliners. Single Level Living. Walk in shower.
Fridge, microwave, oven, stovetop

Recliners. Single Level Living. Walk in shower.

10.0 out of 10, Exceptional, (19)
"This house was super clean and perfect for our stay while I received radiation at Mayo.. would recommend!! "
Recliners. Single Level Living. Walk in shower.
Elton Hills Park Quite 3-bedroom Spacious Home
Smart TV, books

Elton Hills Park Quite 3-bedroom Spacious Home

9.2 out of 10, Wonderful, (5)
"Clean little place with space for our family staying to visit our son at UMR. Would have liked there to be a large bowl for serving popcorn. "
The price is AED 496
AED 1,209 total
includes taxes & fees
6 Aug - 7 Aug
Elton Hills Park Quite 3-bedroom Spacious Home
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (88)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Lots of charm and only blocks away from the Root River and Bike trails
TV, DVD player, books

Lots of charm and only blocks away from the Root River and Bike trails

9.8 out of 10, Exceptional, (23)
"Would stay here again!"
Lots of charm and only blocks away from the Root River and Bike trails
The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air
Game room

The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air

9.8 out of 10, Exceptional, (28)
"A perfect place to gather after a day of sight seeing. "
The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air
Park in the Garage and Walk to Mayo Clinic
Interior

Park in the Garage and Walk to Mayo Clinic

10.0 out of 10, Exceptional, (59)
"Cozy house that quick and easy to get to and from the hospital. Easy access to restaurants and all the main amenities that you need. "
Park in the Garage and Walk to Mayo Clinic
Magical Nest Hideaway
Exterior

Magical Nest Hideaway

10.0 out of 10, Exceptional, (119)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway
Silver Lake Oasis
Property grounds

Silver Lake Oasis

9.6 out of 10, Exceptional, (36)
"A nice little place, well kept and just as advertised."
Silver Lake Oasis
Are you traveling to Rochester? Be our guest!! <br>
Fridge, microwave, oven, stovetop

Are you traveling to Rochester? Be our guest!! <br>

9.8 out of 10, Exceptional, (20)
"This was a very nice place to stay for a weekend. We had 4 people and it was perfect little place. Shelly the manager was quickly available and it was nice and clean."
Are you traveling to Rochester? Be our guest!! <br>
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
Exterior detail

Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio

10.0 out of 10, Exceptional, (5)
"A lovely home that was so comfortable for us to stay in "
The price is AED 602
AED 1,687 total
includes taxes & fees
5 Aug - 6 Aug
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
The Best of Southwest Rochester, MN
Living area

The Best of Southwest Rochester, MN

The price is AED 459
AED 1,332 total
includes taxes & fees
8 Aug - 9 Aug
The Best of Southwest Rochester, MN
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Smart TV, fireplace, video games, DVD player

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (71)
"We had stayed at this property a couple years ago and this stay was just as great as the first. We had family ages 6-70 and everyone really enjoyed their stay. There was plenty of space to be together but enough rooms to have some space too. Everyone enjoyed the games and pool room."
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Luxury Stay/ Theater / Pool Table / Dogs Welcome
Fridge, microwave, stovetop, coffee/tea maker

Luxury Stay/ Theater / Pool Table / Dogs Welcome

2.0 star property
10.0 out of 10, Exceptional, (14)
"We had a great experience staying; the property was clean and a wonderful layout, communication was great and we would definitely stay here again!!"
Luxury Stay/ Theater / Pool Table / Dogs Welcome
Vintage Lustron Home Piece of History
Smart TV, books

Vintage Lustron Home Piece of History

10.0 out of 10, Exceptional, (20)
"We've stayed here several times and enjoy it every time. We enjoy visiting the area and exploring what it has to offer while visiting friends"
The price is AED 595
AED 909 total
includes taxes & fees
21 Jul - 22 Jul
Vintage Lustron Home Piece of History
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Fridge, microwave, oven, stovetop

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (31)
"This home is Central to the Mayo clinic The home is very nice and clean with everything you could possibly need for your stay. We would be back in a few months and definitely be staying here"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Exterior

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

10.0 out of 10, Exceptional, (9)
"Great little house close to several antique and thrift shops! "
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free