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Our top choices for St. Charles vacation homes

1. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (172 reviews)
"This was perfect place for our 2 night stay. Clean and comfortable and at the right price!"
United States
Pam N.
The price is AED 378
AED 655 total
includes taxes & fees
7 Nov - 8 Nov
Magical Nest Hideaway

2. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (25 reviews)
"Very clean place with a very welcoming environment made us feel right at home!!"
United States
Nadaley W.
The price is AED 340
AED 828 total
includes taxes & fees
11 Nov - 12 Nov
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

3. UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK

UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
East Side Pioneers
UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK

4. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
The price is AED 499
AED 751 total
includes taxes & fees
17 Nov - 18 Nov
Vintage Lustron Home Piece of History

5. 1mile Mayo 2 step entry Encourage CoveredByFaith

1mile Mayo 2 step entry Encourage CoveredByFaith
Parkway
10.0 out of 10, Exceptional, (2 reviews)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
The price is AED 415
AED 1,115 total
includes taxes & fees
18 Nov - 19 Nov
1mile Mayo 2 step entry Encourage CoveredByFaith

6. The Little House | 1 mi from downtown, Love Pets!

The Little House | 1 mi from downtown, Love Pets!
Slatterly Park
10.0 out of 10, Exceptional, (23 reviews)
"Beautiful little house and comfortable stay."
United States
Cheryl P.
The Little House | 1 mi from downtown, Love Pets!

7. 1mile to Mayo 2 step entry Brave Covered By Faith

1mile to Mayo 2 step entry Brave Covered By Faith
Parkway
10.0 out of 10, Exceptional, (11 reviews)
"This was a PERFECT place to stay if you're going to the Mayo!Jessica is very easy to work with and incredibly responsive!"
United States
Kristin T.
The price is AED 334
AED 1,004 total
includes taxes & fees
9 Nov - 10 Nov
1mile to Mayo 2 step entry Brave Covered By Faith

8. Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Rochester
10.0 out of 10, Exceptional, (9 reviews)
"Lovely house, open and bright feel, great back yard for dogs, comfortable beds, convenient neighborhood."
United States
Kay L.
The price is AED 581
AED 1,731 total
includes taxes & fees
7 Nov - 8 Nov
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven

9. ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry

ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry
East Side Pioneers
9.0 out of 10, Wonderful, (15 reviews)
"Great place!"
United States
Jeremiah E.
The price is AED 614
AED 1,315 total
includes taxes & fees
18 Nov - 19 Nov
ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry

10. Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
Rochester
10.0 out of 10, Exceptional, (11 reviews)
"Nice place to stay, close to all the activities we wanted to do."
United States
Kimberly K.
The price is AED 581
AED 1,732 total
includes taxes & fees
9 Nov - 10 Nov
Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.

11. Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Slatterly Park
10.0 out of 10, Exceptional, (46 reviews)
"Immaculate house with room for us to spread out! Perfect stay."
United States
Sarah F.
The price is AED 733
AED 916 total
includes taxes & fees
15 Nov - 16 Nov
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

12. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveler
The price is AED 419
AED 1,113 total
includes taxes & fees
15 Nov - 16 Nov
Close to Mayo/Shops, 1 step entry Covered By Faith

13. Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Washington
10.0 out of 10, Exceptional, (49 reviews)
"Great place to stay. Near Mayo, grocery, and other shopping. Very dog friendly. Would stay again."
United States
Ann G.
The price is AED 698
AED 875 total
includes taxes & fees
21 Nov - 22 Nov
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

14. Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Rochester
10.0 out of 10, Exceptional, (6 reviews)
"We enjoyed our stay here. Nice location easy to get to things in Rochester. "
United States
Jonathan P.
The price is AED 1,208
AED 1,514 total
includes taxes & fees
10 Nov - 11 Nov
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic

15. Mayo Clinic Cottage - Power Bed & Recliners

Mayo Clinic Cottage - Power Bed & Recliners
Northrup
The price is AED 557
AED 1,381 total
includes taxes & fees
7 Nov - 8 Nov
Mayo Clinic Cottage - Power Bed & Recliners

16. 2 bed/2 bath Beautiful Home in Historic Rochester· 2 Mins to Mayo Clinic Campus

2 bed/2 bath Beautiful Home in Historic Rochester· 2 Mins to Mayo Clinic Campus
Folwell
The price is AED 488
AED 862 total
includes taxes & fees
27 Nov - 28 Nov
2 bed/2 bath Beautiful Home in Historic Rochester· 2 Mins to Mayo Clinic Campus

17. The Hen House Retreat - A Comfortable Place to Roost

The Hen House Retreat - A Comfortable Place to Roost
Highland
9.6 out of 10, Exceptional, (110 reviews)
"We enjoyed our stay. Thank you for the clean property and well described property."
United States
Lydia F.
The price is AED 595
AED 694 total
includes taxes & fees
8 Nov - 9 Nov
The Hen House Retreat - A Comfortable Place to Roost

18. HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky

HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky
Kutzky Park
10.0 out of 10, Exceptional, (4 reviews)
"Fun neighborhood good bars and restaurants "
United States
David M.
HartHouse | 5 Min Walk to Mayo St Marys, Historic Kutzky

19. Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard

Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard
Rochester
10.0 out of 10, Exceptional, (1 review)
"The Little Nest was a perfect place for us to stay while in Rochester. It was easy access to where we needed to be check-in was a breeze and Becca our host was above and beyond."
United States
pat o.
The price is AED 476
AED 1,438 total
includes taxes & fees
9 Nov - 10 Nov
Little Nest | 2 mi to Mayo Clinic, 2 bed w/Lg Yard

20. Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons

Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
Historic Downtown Winona
9.8 out of 10, Exceptional, (37 reviews)
"Very clean, great hosts, fully equipped we everything we needed. "
United States
Amy B.
The price is AED 643
AED 773 total
includes taxes & fees
17 Nov - 18 Nov
Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top reviews in St. Charles