Search Vacation Homes in St. Charles

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Compare 197 Vacation Homes in St. Charles with updated reviews, rates, and availability.

Magical Nest Hideaway

10.0 out of 10, Exceptional, (115)
"The wild turkeys and deer who greeted us in the morning. "
Magical Nest Hideaway

Bluffside cottage with gorgeous river views

10.0 out of 10, Exceptional, (27)
"So cute/quiet/clean with gorgeous views of the river!"
Bluffside cottage with gorgeous river views

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (117)
"Easy access to Mayo and the host was fantastic "
Century Cottage-PERFECT for Mayo & downtown visitors!

Lots of charm and only blocks away from the Root River and Bike trails

9.8 out of 10, Exceptional, (19)
"Would stay here again!"
Lots of charm and only blocks away from the Root River and Bike trails

Recliners. Single Level Living. Walk in shower.

10.0 out of 10, Exceptional, (18)
"This house was super clean and perfect for our stay while I received radiation at Mayo.. would recommend!! "
Recliners. Single Level Living. Walk in shower.

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

10.0 out of 10, Exceptional, (44)
"Would stay again! Thank you!"
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

Vintage Lustron Home Piece of History

10.0 out of 10, Exceptional, (20)
"We've stayed here several times and enjoy it every time. We enjoy visiting the area and exploring what it has to offer while visiting friends"
The price is AED 551
AED 850 total
includes taxes & fees
2 Jun - 3 Jun
Vintage Lustron Home Piece of History

Family friendly in the peaceful heart of town

10.0 out of 10, Exceptional, (92)
"We had a lovely and comfortable stay for Thanksgiving. Walkable or very short drive to the sights and amenities of Winona! "
Family friendly in the peaceful heart of town

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (44)
"Quaint and very well supplied with anything we needed. Great location near Mayo, restaurants and shopping. Definitely would recommend this place."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

1 mi. from Mayo Clinic; Cozy, Clean

9.6 out of 10, Exceptional, (91)
"It all went smooth. Very nice hosts."
1 mi. from Mayo Clinic; Cozy, Clean

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

10.0 out of 10, Exceptional, (14)
"Very clean and comfortable. "
The price is AED 955
AED 1,174 total
includes taxes & fees
4 Jun - 5 Jun
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

9.4 out of 10, Exceptional, (16)
"Everything was excellent! Super happy"
The price is AED 496
AED 1,209 total
includes taxes & fees
7 Jun - 8 Jun
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

The Best of Southwest Rochester, MN

The Best of Southwest Rochester, MN

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (70)
"Perfect for a family get away. Kids loved the pool. "
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

10.0 out of 10, Exceptional, (7)
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (82)
"We had a wonderful stay. The house is amazing with plenty of room for more than my wife & I. The couches & beds were comfortable and as close to home as it could be without being home! The location to St. Mary’s & Mayo Clinic is perfect & this all helped my recovery after surgery go perfectly! Thank you for a wonderful stay! "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (14)
"The house was great! Kitchen is well stocked and we felt right at home. We would love to come back again!"
Within walking distance of all the amenities! Bike the trail~ float the river

1 mile to Mayo 2 step entry Brave Covered By Faith

2.0 star property
10.0 out of 10, Exceptional, (9)
"The short two day stay we had was amazing. "
1 mile to Mayo 2 step entry Brave Covered By Faith

Charming Brick Farmhouse with a Touch of Elegance. -Winona

10.0 out of 10, Exceptional, (124)
"This property is amazing! By far the best VRBO property I have had the pleasure to stay."
The price is AED 1,175
AED 1,898 total
includes taxes & fees
9 Jun - 10 Jun
Charming Brick Farmhouse with a Touch of Elegance. -Winona

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (8)
"What an amazing property! This little home was perfect! I highly recommend anyone to rent this little home! "
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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