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Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Travelers start their day with a hearty breakfast buffet at this convenient hotel, perfectly positioned for exploring the attractions of St. Louis

Choose dates to view prices

Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
The current price is AED 435
AED 501 total
includes taxes & fees
3 Apr - 4 Apr

Room options

Available filters for rooms
Showing 7 of 7 rooms

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.8 out of 10
Exceptional
(36 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(14 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(27 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(20 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking | In-room safe, blackout drapes, iron/ironing board

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

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The price is AED 328
AED 379 total
includes taxes & fees
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About the neighborhood

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. BounceU of St. Louis and Grant's Farm are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • St. Louis Cardinals Baseball.
    Busch Stadium
    16 min drive - 27.2 km
  • Gateway Arch featuring a monument, night scenes and a park
    Gateway Arch
    17 min drive - 27.8 km
  • Union Station, St. Louis, MO
    St. Louis Union Station
    18 min drive - 27.2 km
  • Halloween 2019 at the zoo.
    St. Louis Zoo
    21 min drive - 26.3 km
  • Barnes Jewish South Campus
    5 min walk - 0.4 km

Getting around

  • Kirkwood Station
    14 min drive
  • St. Louis Lambert Intl. Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Popeyes Louisiana Kitchen
    3 min walk
  • Hardee's / Red Burrito
    10 min walk
  • Rich & Charlie's Italian Restaurant
    3 min drive

About this property

Hampton Inn & Suites St. Louis/South I-55

Hotel near Mississippi River
At Hampton Inn & Suites St. Louis/South I-55, you can look forward to a free breakfast buffet, a grocery/convenience store, and dry cleaning/laundry services. Free in-room WiFi is available to all guests, along with a fireplace in the lobby and a gym.
Additional perks include:
  • An indoor pool
  • Free self parking
  • Express check-in, free newspapers, and a computer station
  • Laundry services, a vending machine, and 1 meeting room
  • Guest reviews speak highly of the breakfast and helpful staff
Room features
All 92 rooms offer comforts such as air conditioning, as well as perks like free WiFi and safes. Guest reviews speak positively of the clean rooms at the property.
More conveniences in all rooms include:
  • Bathrooms with free toiletries and hair dryers
  • 37-inch LCD TVs with cable channels
  • Wardrobes/closets, refrigerators, and microwaves

Similar properties

Property amenity
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 1,001 reviews
The price is AED 492
AED 566 total
includes taxes & fees
3 Apr - 4 Apr
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Compare similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of 27 March 2026, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on 3 April 2026 start from AED 435, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Check-out is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of BounceU of St. Louis and St Anthony's. Suson Park and Kindred Hospital St. Louis South are also within 3 mi (5 km).

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Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.8

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 820 out of 1000 reviews
Rating 8 - Good. 129 out of 1000 reviews
Rating 6 - Okay. 27 out of 1000 reviews
Rating 4 - Poor. 5 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

Reviews

Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room.
Stayed 2 nights in Mar 2026
Verified

8/10 Good

josh

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

kevin

Liked: Cleanliness, amenities, property conditions & facilities
The room was very much attended to. It was excellent. The biggest drawback was Internet. My wife felt a little close then because of the city view and not the Park view.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified

2/10 Terrible

Lonnie

The bed was the absolute worst bed I've ever slept in. Lumpy and broken down
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Yvonne

The room was excellent and so was the staff.
Stayed 1 night in Jan 2026
Verified

2/10 Terrible

Jason

Liked: Staff & service
Disliked: Cleanliness, amenities
The room was supposed to be a king suite with a jacuzzi tub and spent 350 on it and ended up getting a standard suite handicapped accessible
Stayed 2 nights in Dec 2025
Verified

8/10 Good

Gretchen

Clean room
Stayed 3 nights in Dec 2025
Verified

10/10 Excellent

SHELLY

Liked: Cleanliness, staff & service, amenities
Clean room, good breakfast. Nice, safe area. But the staff was the best I have encountered in a long time. From check in, check out to the breakfast staff. I cannot say enough. We stayed 12/6/25 - one night and I would come back in a heartbeat.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025
Verified

2/10 Terrible

Tabitha

Liked: Cleanliness
Disliked: Staff & service
Upon check in at 4am which I understand is not check in time there was a hiccup. On hotels.com I booked check-in Monday check out Tuesday and paid online almost two hundred dollars and change. During check in the lady pointed out that I booked an accesible room and did I want. No, I said but the app didn’t show me another room with two beds. I wouldn’t want to take an accesible room away from somebody who might need it. So, she said she could switch it no problem or changes. I go to sign the papers and it had me checking out same day, but that’s not what my itinerary on the app and in my email stated almost two hundred dollars paid for check out Tuesday. She would not honor my booking with hotels.com the way it was booked. She wouldn’t let me pay to check in early because it was 4 am Monday and I was exhausted and also had my dog which was almost a hundred per night. I had to pay almost four hundred because they count 4am as Sunday. Whats crazy is the system only charged me one night dog fee, so it recognized my dog was there for 1 night but not me. I paid for insurance on hotels.com and contacted them and they contacted the hotel. I got refunded the original amountfrom the website. There’s that, but I stayed in another hotel recently that let me check in around midnight for just an extra 20 added to my total. Charging a whole extra night for checking in 7 hours early (I was told at 11 it turns into the next day) seems a bit much. A lesson learned if I ever stay here again.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Jessica

Liked: Cleanliness, property conditions & facilities, room comfort
The room was very nice and seemed pretty updated. Bathroom was huge for a hotel bathroom. The shower was underwhelming and the beds weren't the most comfortable. Overall it was pretty nice and i would stay here again if im in the area.
Stayed 1 night in Nov 2025
Verified

8/10 Good

Cynthia

Liked: Cleanliness, staff & service, amenities
The room was clean and we just needed a bed to sleep in! It was fine
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Samiha

Nice room! regular cleaning. Good breakfast. Staffs are welcoming.
Stayed 3 nights in Nov 2025
Verified

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Lísbeth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I’m a traveling band mom, so I’ve been in three different hotel franchises in the last three weeks. This was the best! When I walked in, I was shocked at how crisp and clean everything was. Great service, they let me check in early, which was extremely helpful. The room was noiiiiiice! And I really need to know where I can buy their shampoo and conditioner, because my hair has never been so manageable. I didn’t have time to swim, but their pool has play stuff and it’s nice and warm in there. I will be back! It’s a great distance from St Louis, you can get there in no time and still be in the burbs
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025
Verified

8/10 Good

Melinda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
yes
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Vicenta Fe

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I liked everything about this Hampton Inn, from the staff, room, amenities, breakfast, cleanliness, location and parking are all superb. Will definitely come back
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Didn't use
Stayed 3 nights in Oct 2025
Verified

8/10 Good

Fernando

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was so helpful. We came for a funeral. Our room was not, ready, we needed to check in early. I was in consent contact with your staff about early check in, we needed to change clothes before going to the funeral. I was told they would do everything to accommodate us. The rooms were being cleaned when we arrived, but we would be late if we waited to change, so your staff allowed use to change in a vacant conference room, it was 5 of us. They check to see how long it would take us to get to the funeral. The staff was just so caring and sincere. We made it on time to share this difficult time with our family. Blessings to your staff. The Sanders family.
Stayed 1 night in Sep 2025