St. Charles Historic District, MO

St. Louis

A wooden bridge with metal trusses, surrounded by trees.
A historic brick building with arched doorways and a sign that reads "Hot Goods Pen House."
A rustic wooden church with a cross on the roof and a bell.
A person holding a guitar.
A red train car with a ladder, set against a sunset sky.

Stay near popular St. Charles Historic District attractions

A brick-paved street lined with historic buildings and a yellow fire hydrant.

Historic Main Street

9.4/10 (538 reviews)
You can learn about the history of St. Charles with a trip to Historic Main Street. Check out the shops and top-notch restaurants in this family-friendly area.
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St. Charles Historic District Hotel Deals

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
The price is AED 491 per night from Aug 16 to Aug 17
AED 491
AED 564 total
16 Aug - 17 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,049 reviews)
"Our only issue was ever time we left the room we had to get a new key cause their lock system is outdated and not working properly."

Reviewed on 16 July 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is AED 355 per night from Aug 9 to Aug 10
AED 355
AED 415 total
9 Aug - 10 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is AED 477 per night from Jul 19 to Jul 20
AED 477
AED 611 total
19 Jul - 20 Jul
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,182 reviews)
"Nasty room. Smelled of smoke even though it was a smoke free room. TV sucked with speakers and connecting for streaming services. Coffee maker was on a cut out shelf in the bathroom! Soaker tub nor sink plugs worked."

Reviewed on 17 July 2026

Hollywood Casino & Hotel St. Louis
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
The price is AED 302 per night from Aug 16 to Aug 17
AED 302
AED 370 total
16 Aug - 17 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,631 reviews)
"A urine smell, first room straight up stanked couldn’t even pass the door. Next room smelled better but oddly enough after room service or while I was gone…somehow the smell came to next room idk how to feel about that"

Reviewed on 17 July 2026

Forest Park Hotel by MDR
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is AED 331 per night from Aug 9 to Aug 10
AED 331
AED 389 total
9 Aug - 10 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn St. Louis Airport
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
The price is AED 532 per night from Jul 20 to Jul 21
AED 532
AED 633 total
20 Jul - 21 Jul
includes taxes & fees
Book a stay at this boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ...
9/10 Wonderful! (1,994 reviews)
"Nice hotel, great location."

Reviewed on 17 July 2026

Moonrise Hotel
See all 1,750 properties in St. Charles Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in St. Charles Historic District

Find the best St. Charles Historic District areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

An ornate hall with arched ceilings and intricate patterns.
Photo by Terry Eaves
Open Photo by Terry Eaves

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

St. Charles Historic District, MO

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