A modern building with a unique triangular roof and a central spire.

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Check prices for these dates

Next weekend
24 Jul - 26 Jul
In two weeks
31 Jul - 2 Aug

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Our top choices for Santa Lucia hotels

Front of property

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (684 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is AED 454
AED 517 total
includes taxes & fees
23 Jul - 24 Jul
Grande Albergo Alfeo
Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (288 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is AED 726
AED 840 total
includes taxes & fees
24 Jul - 25 Jul
Caportigia Boutique Hotel
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is AED 244
AED 278 total
includes taxes & fees
21 Jul - 22 Jul
Nostos rooms & Apartments
Porch

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is AED 306
AED 349 total
includes taxes & fees
19 Jul - 20 Jul
Piccolo Hotel Casa Mia
Breakfast area

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (130 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is AED 789
AED 910 total
includes taxes & fees
21 Jul - 22 Jul
Giuggiulena Villa
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is AED 409
AED 467 total
includes taxes & fees
1 Aug - 2 Aug
Lakkios
Triple Room, Balcony | Balcony

B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"Clean, good location. "
United States
Salvatore
The price is AED 332
AED 378 total
includes taxes & fees
30 Jul - 31 Jul
B&B Nike
1 bedroom, down comforters, minibar, in-room safe

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is AED 840
AED 966 total
includes taxes & fees
19 Jul - 20 Jul
Re Dionisio Luxury Suites
Suite | Soundproofing, WiFi (free)

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (43 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is AED 471
AED 537 total
includes taxes & fees
26 Jul - 27 Jul
Hotel Palazzo Cavalieri
Luxury Quadruple Room, Balcony, City View | In-room safe, desk, soundproofing, iron/ironing board

B&B IL MORO

B&B IL MORO
Santa Lucia
The price is AED 236
AED 365 total
includes taxes & fees
19 Jul - 20 Jul
B&B IL MORO
View from room

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (13 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is AED 477
AED 544 total
includes taxes & fees
22 Jul - 23 Jul
Calafatari B&B
Superior Triple Room, Sea View | Terrace/patio

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (35 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is AED 625
AED 712 total
includes taxes & fees
21 Jul - 22 Jul
Fortaleza Charme House
Lobby lounge

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is AED 362
AED 412 total
includes taxes & fees
21 Jul - 22 Jul
Regina Margherita
Double Room | Premium bedding, desk, cribs (surcharge), rollaway beds (surcharge)

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is AED 264
AED 301 total
includes taxes & fees
19 Jul - 20 Jul
B&B Siracusa
Premium bedding, down comforters, memory foam beds, in-room safe

Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is AED 553
AED 631 total
includes taxes & fees
25 Jul - 26 Jul
Eos Sea View Apartment
Free daily buffet breakfast

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is AED 377
AED 430 total
includes taxes & fees
19 Jul - 20 Jul
San Nicola Rooms Siracusa
Double Room, 1 King Bed, Sea View, Tower | In-room safe, desk, soundproofing, iron/ironing board

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is AED 984
AED 1,124 total
includes taxes & fees
29 Jul - 30 Jul
Casa Miranda Boutique
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk

Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (19 reviews)
"The owner was really nice and helpful! Really enjoyed our stay here."
Finland
Kirsi
The price is AED 396
AED 452 total
includes taxes & fees
26 Jul - 27 Jul
Fortuna Guest House
WiFi (free)

B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is AED 156
AED 226 total
includes taxes & fees
1 Aug - 2 Aug
B&B L'INFIORESCENZA
Comfort Triple Room, Balcony, Ocean View | View from room

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is AED 315
AED 359 total
includes taxes & fees
26 Jul - 27 Jul
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
130 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
288 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk
Fortuna Guest House
1.0 star property
9.2
Wonderful
19 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
282 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Beautiful hotel, breakfast spread was brilliant and room extremely clean. Staff were all so lovely and attentive. We had a great first afternoon at the pool bar and were very well looked after by a young man who went above and beyond - sorry we did not catch his name."
Ross 4-night trip
Posted 1 day ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World

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Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels can I expect to find in Santa Lucia?
Expedia has 310 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.