A modern building with a unique triangular roof and a central spire.

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Our top choices for Santa Lucia hotels

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (291 reviews)
"Lovely hotel in a great spot, very helpful staff."
Australia
Mandy
The price is AED 776
AED 897 total
includes taxes & fees
9 Sep - 10 Sep
Caportigia Boutique Hotel

2. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (692 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is AED 475
AED 542 total
includes taxes & fees
23 Sep - 24 Sep
Grande Albergo Alfeo

3. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (285 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is AED 280
AED 319 total
includes taxes & fees
5 Oct - 6 Oct
Nostos rooms & Apartments

4. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is AED 885
AED 1,016 total
includes taxes & fees
6 Sep - 7 Sep
Re Dionisio Luxury Suites

5. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is AED 381
AED 434 total
includes taxes & fees
14 Sep - 15 Sep
Piccolo Hotel Casa Mia

6. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (131 reviews)
"Hidden gem! The staff was extremely welcoming and helpful throughout our visit. Can't beat a room that looks out over the water and is a short walk into town. Would highly recommend!"
United States
James
The price is AED 810
AED 934 total
includes taxes & fees
2 Oct - 3 Oct
Giuggiulena Villa

7. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"Clean room and well located."
United Kingdom
Hanna
The price is AED 407
AED 480 total
includes taxes & fees
17 Sep - 18 Sep
Lakkios

8. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (39 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is AED 779
AED 888 total
includes taxes & fees
5 Oct - 6 Oct
Fortaleza Charme House

9. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is AED 615
AED 701 total
includes taxes & fees
2 Oct - 3 Oct
Calafatari B&B

10. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (89 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is AED 298
AED 339 total
includes taxes & fees
4 Oct - 5 Oct
B&B Nike

11. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is AED 357
AED 407 total
includes taxes & fees
6 Sep - 7 Sep
Hotel Palazzo Cavalieri

12. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is AED 291
AED 332 total
includes taxes & fees
11 Sep - 12 Sep
B&B Siracusa

13. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is AED 443
AED 505 total
includes taxes & fees
5 Oct - 6 Oct
San Nicola Rooms Siracusa

14. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is AED 746
AED 864 total
includes taxes & fees
6 Sep - 7 Sep
Casa Miranda Boutique

15. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is AED 290
AED 331 total
includes taxes & fees
1 Oct - 2 Oct
Regina Margherita

16. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is AED 211
AED 241 total
includes taxes & fees
5 Oct - 6 Oct
Gymnasium

17. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is AED 316
AED 360 total
includes taxes & fees
29 Sep - 30 Sep
B&B IL MORO

18. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is AED 359
AED 410 total
includes taxes & fees
9 Sep - 10 Sep
Hotel Mediterraneo

19. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is AED 222
AED 351 total
includes taxes & fees
30 Sep - 1 Oct
Le Camere Luxsury Rooms

20. Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is AED 1,182
AED 1,347 total
includes taxes & fees
5 Oct - 6 Oct
Eos Sea View Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
42 reviews
View
Suite | Soundproofing, WiFi (free)
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
44 reviews
View
Porch
Piccolo Hotel Casa Mia
3.0 star property
8.6
Excellent
386 reviews
View
1 bedroom, down comforters, minibar, in-room safe
Re Dionisio Luxury Suites
3.0 star property
8.8
Excellent
58 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels can I expect to find in Santa Lucia?
Expedia has 314 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.