Top Santa Lucia Hotels

A modern building with a unique triangular roof and a central spire.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels in Santa Lucia

Property	Property class	Guest rating
Giuggiulena Villa	3.0 star property	10.0 Exceptional 130 reviews	View
Calafatari B&B	3.0 star property	9.8 Exceptional 17 reviews	View
Caportigia Boutique Hotel	5.0 star property	9.4 Exceptional 290 reviews	View
Lakkios	3.0 star property	9.2 Wonderful 74 reviews	View
Hotel Palazzo Cavalieri	4.0 star property	9.0 Wonderful 44 reviews	View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Teatro dei Pupi and Cathedral of Syracuse while you're in town.

See properties

Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

See properties

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

See properties

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

See properties

Aerial view of Ortigia, historical centre of the city of Syracuse. Aerial view of Maniace fortress in Ortigia, Sicily, Italy. Sanctuary "Our Lady of Tears" is at the background

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

See properties

Top Santa Lucia Hotel Reviews

Domus Mariae Albergo

10/10 Excellent

"The room was spacious comfortable with a great view the location was so lovely, when I had an issue with my shower the staff relocated me to the another room And they constantly checked in A great hotel and experience"

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"Overall an excellent stay. Our suite (with a private pool) was modern, clean and comfortable - most critically with a soft bed (italian beds are usually so hard) and effective but quiet aircon (so you could have it on all night). At the pool there are comfy sunloungers and we always had brand new fluffy pool towels. The main pool was usually very busy - but not an issue for us as we camped out at the adults pool. Breakfast buffet was excellent. Lunch and drinks at Lime Bar were also always to a high standard. The evening buffet, and the a-la carte restaurants were a bit hit & miss - the pizza restaurant the best of the bunch. Staff very helpful, maybe just too few of them on occassion. Note that this hotel really is off the beaten track. Brucoli village is close - but there is nothing there to see or do. Don't bother going and certainly pay for the water taxi from the hotel. Overall - thoroughly recommend."

Fortaleza Charme House

10/10 Excellent

"This is a lovely hotel. It is a short walk over the bridges to Ortigia to all of the lovely things to see on the island. The rooms are really spacious and comfortable with everything you need including a little kitchen space if you want to eat in (although there are so many lovely restaurants nearby). Nicole and Francesco where wonderful. We had helpful information from both of them about our arrival and also some fantastic recommendations for places to eat. The hotel was peaceful and cool in the heat. It was a great place to stay."

House with Big Terrace in Seaside, Syracuse - Ortigia

8/10 Good

"Le logement est tres bien placé avec une petite cale en bas qui permet de se baigner. La terrasse vue mer est superbe. La salle de bain est fonctionnelle mais l’eau de la douche s’écoule mal. En ce qui concerne la Clim, elle fonctionne mais n’était pas assez puissante au vu des fortes chaleurs que nous avons eu et de l’isolation simple. Nous avons eu très chaud dans le logement du coup. La communication avec l’hôte s’est bien passée, il est très réactif."

Hotel Parco delle Fontane

10/10 Excellent

"Very nice hotel outside of busy area but easy to access downtown Ortigia and Siracusa Unfortunately was only there for one night but pool looked wonderful and historic ambiance in hotel was interesting to see. Parking was free and breakfast was wonderful with so many options! Will definitely revisit when I’m the area again!"

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.

How many hotels can I expect to find in Santa Lucia?

Expedia has 312 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Find hotels in Santa Lucia, Syracuse

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Lucia hotels

1. Grande Albergo Alfeo

2. Caportigia Boutique Hotel

3. Nostos rooms & Apartments

4. Lakkios

5. B&B Nike

6. Piccolo Hotel Casa Mia

7. Calafatari B&B

8. Fortaleza Charme House

9. Hotel Palazzo Cavalieri

10. Re Dionisio Luxury Suites

11. Regina Margherita

12. B&B IL MORO

13. Giuggiulena Villa

14. San Nicola Rooms Siracusa

15. B&B Siracusa

16. Hotel Mediterraneo

17. Casa Miranda Boutique

18. Fortuna Guest House

19. Eos Sea View Apartment

20. Isonzo Suites

Compare popular hotels in Santa Lucia

Where to stay in Santa Lucia

Ortigia

Neapolis

Grottasanta

Tiche

Acradina

Top Santa Lucia Hotel Reviews

Domus Mariae Albergo

Frequently asked questions