A modern building with a unique triangular roof and a central spire.

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Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

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Our top choices for Santa Lucia hotels

Rooftop terrace

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (291 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is AED 842
AED 969 total
includes taxes & fees
30 Aug - 31 Aug
Caportigia Boutique Hotel
1 bedroom, down comforters, minibar, in-room safe

2. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is AED 884
AED 1,015 total
includes taxes & fees
28 Aug - 29 Aug
Re Dionisio Luxury Suites
Front of property

3. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (689 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is AED 353
AED 402 total
includes taxes & fees
13 Sep - 14 Sep
Grande Albergo Alfeo
Coffee/tea maker, electric kettle

4. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (285 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is AED 292
AED 333 total
includes taxes & fees
18 Sep - 19 Sep
Nostos rooms & Apartments
Porch

5. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is AED 312
AED 356 total
includes taxes & fees
29 Aug - 30 Aug
Piccolo Hotel Casa Mia
Breakfast area

6. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (130 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is AED 877
AED 1,007 total
includes taxes & fees
7 Sep - 8 Sep
Giuggiulena Villa
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing

7. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"Clean room and well located."
United Kingdom
Hanna
The price is AED 430
AED 491 total
includes taxes & fees
26 Aug - 27 Aug
Lakkios
Suite | Soundproofing, WiFi (free)

8. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is AED 426
AED 486 total
includes taxes & fees
6 Sep - 7 Sep
Hotel Palazzo Cavalieri
Triple Room, Balcony | Balcony

9. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is AED 280
AED 319 total
includes taxes & fees
23 Sep - 24 Sep
B&B Nike
Superior Triple Room, Sea View | Terrace/patio

10. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (38 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is AED 687
AED 783 total
includes taxes & fees
26 Aug - 27 Aug
Fortaleza Charme House
View from room

11. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is AED 579
AED 661 total
includes taxes & fees
26 Aug - 27 Aug
Calafatari B&B
Free daily buffet breakfast

12. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is AED 485
AED 553 total
includes taxes & fees
24 Sep - 25 Sep
San Nicola Rooms Siracusa
Double Room | Premium bedding, desk, cribs (surcharge), rollaway beds (surcharge)

13. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is AED 287
AED 327 total
includes taxes & fees
27 Aug - 28 Aug
B&B Siracusa
Comfort Triple Room, Balcony, Ocean View | View from room

14. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is AED 360
AED 410 total
includes taxes & fees
11 Sep - 12 Sep
Hotel Mediterraneo
Luxury Quadruple Room, Balcony, City View | In-room safe, desk, soundproofing, iron/ironing board

15. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is AED 313
AED 455 total
includes taxes & fees
24 Sep - 25 Sep
B&B IL MORO
Lobby lounge

16. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is AED 310
AED 354 total
includes taxes & fees
10 Sep - 11 Sep
Regina Margherita
Double Room, 1 King Bed, Sea View, Tower | In-room safe, desk, soundproofing, iron/ironing board

17. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is AED 630
AED 736 total
includes taxes & fees
2 Sep - 3 Sep
Casa Miranda Boutique
Exclusive Room | In-room safe, soundproofing, iron/ironing board (on request)

18. Isonzo Suites

Isonzo Suites
Santa Lucia
8.6 out of 10, Excellent, (8 reviews)
"."
Italy
Gianluca
The price is AED 367
AED 546 total
includes taxes & fees
11 Sep - 12 Sep
Isonzo Suites
Premium bedding, down comforters, memory foam beds, in-room safe

19. Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is AED 628
AED 716 total
includes taxes & fees
28 Aug - 29 Aug
Eos Sea View Apartment
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk

20. Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (19 reviews)
"The owner was really nice and helpful! Really enjoyed our stay here."
Finland
Kirsi
The price is AED 335
AED 381 total
includes taxes & fees
16 Sep - 17 Sep
Fortuna Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
130 reviews
View
View from room
Calafatari B&B
3.0 star property
9.8
Exceptional
17 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
285 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
42 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Aerial view of Ortigia, historical centre of the city of Syracuse. Aerial view of Maniace fortress in Ortigia, Sicily, Italy. Sanctuary "Our Lady of Tears" is at the background

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Everything was great Staff was amazing very helpful Breakfast was very good"
Helena 2-night trip
Posted 14 hours ago
Algila' Ortigia Charme Hotel

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels can I expect to find in Santa Lucia?
Expedia has 314 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.