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Find hotels in Upstate South Carolina, SC from AED 232
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (751 reviews)
The price is AED 404
AED 452 total
includes taxes & fees
19 Jul - 20 Jul

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (511 reviews)
The price is AED 338
AED 368 total
includes taxes & fees
28 Jun - 29 Jun

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (238 reviews)
The price is AED 441
AED 485 total
includes taxes & fees
2 Jul - 3 Jul

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (469 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
2 Jul - 3 Jul

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (855 reviews)
The price is AED 382
AED 420 total
includes taxes & fees
19 Jul - 20 Jul

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,284 reviews)
The price is AED 436
AED 479 total
includes taxes & fees
28 Jun - 29 Jun

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (869 reviews)
The price is AED 547
AED 608 total
includes taxes & fees
6 Jul - 7 Jul

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (809 reviews)
The price is AED 367
AED 411 total
includes taxes & fees
26 Jul - 27 Jul

Deluxe Inn
Deluxe InnMauldin
9.6 out of 10, Exceptional, (4 reviews)
The price is AED 211
AED 232 total
includes taxes & fees
6 Jul - 7 Jul

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,002 reviews)
The price is AED 511
AED 567 total
includes taxes & fees
2 Jul - 3 Jul

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (734 reviews)
The price is AED 309
AED 336 total
includes taxes & fees
4 Jul - 5 Jul

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (627 reviews)
The price is AED 389
AED 432 total
includes taxes & fees
26 Jul - 27 Jul

Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
9.4 out of 10, Exceptional, (502 reviews)
The price is AED 437
AED 485 total
includes taxes & fees
12 Jul - 13 Jul

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,514 reviews)
The price is AED 338
AED 372 total
includes taxes & fees
5 Jul - 6 Jul

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (925 reviews)
The price is AED 337
AED 374 total
includes taxes & fees
26 Jul - 27 Jul

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.2 out of 10, Very Good, (1,002 reviews)
The price is AED 393
AED 437 total
includes taxes & fees
2 Jul - 3 Jul

AC Hotel by Marriott Spartanburg
AC Hotel by Marriott SpartanburgSpartanburg
9.4 out of 10, Exceptional, (636 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
28 Jun - 29 Jun

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,002 reviews)
The price is AED 400
AED 497 total
includes taxes & fees
2 Jul - 3 Jul

Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
9.0 out of 10, Wonderful, (741 reviews)
The price is AED 365
AED 405 total
includes taxes & fees
30 Jun - 1 Jul

SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
9.6 out of 10, Exceptional, (1,000 reviews)
The price is AED 454
AED 500 total
includes taxes & fees
12 Jul - 13 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (80 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center
8/10 Good
More cheap stays in Upstate South Carolina

Urban Boutique Hotel, BW Signature Collection
536 Wade Hampton Blvd Greenville SC
The price is AED 253 per night from Jul 8 to Jul 9
AED 253
AED 278 total
8 Jul - 9 Jul
includes taxes & fees
8/10 Very Good! (1,002 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
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