Photo by Visit Greenville, South Carolina

Find hotels in Upstate South Carolina, SC from AED 251
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (450 reviews)
The price is AED 312
AED 340 total
includes taxes & fees
15 Mar - 16 Mar

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (683 reviews)
The price is AED 421
AED 459 total
includes taxes & fees
5 Apr - 6 Apr

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (2 reviews)
The price is AED 356
AED 701 total
includes taxes & fees
8 Mar - 9 Mar

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (801 reviews)
The price is AED 547
AED 608 total
includes taxes & fees
18 Mar - 19 Mar

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (436 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
4 Apr - 5 Apr

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,099 reviews)
The price is AED 393
AED 433 total
includes taxes & fees
5 Apr - 6 Apr

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (684 reviews)
The price is AED 286
AED 337 total
includes taxes & fees
13 Mar - 14 Mar

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (765 reviews)
The price is AED 344
AED 385 total
includes taxes & fees
15 Mar - 16 Mar

Spartanburg Marriott
Spartanburg MarriottSpartanburg
8.6 out of 10, Excellent, (1,001 reviews)
The price is AED 433
AED 481 total
includes taxes & fees
22 Mar - 23 Mar

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (815 reviews)
The price is AED 415
AED 456 total
includes taxes & fees
16 Mar - 17 Mar

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.0 out of 10, Wonderful, (598 reviews)
The price is AED 378
AED 420 total
includes taxes & fees
22 Mar - 23 Mar

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (691 reviews)
The price is AED 509
AED 565 total
includes taxes & fees
15 Mar - 16 Mar

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,010 reviews)
The price is AED 335
AED 372 total
includes taxes & fees
8 Mar - 9 Mar

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (980 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
8 Mar - 9 Mar

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.2 out of 10, Very Good, (846 reviews)
The price is AED 306
AED 339 total
includes taxes & fees
8 Mar - 9 Mar

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.2 out of 10, Very Good, (1,002 reviews)
The price is AED 387
AED 430 total
includes taxes & fees
15 Mar - 16 Mar

Hotel Hartness
Hotel HartnessGreenville
9.8 out of 10, Exceptional, (666 reviews)
The price is AED 525
AED 701 total
includes taxes & fees
5 Apr - 6 Apr

Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
9.0 out of 10, Wonderful, (682 reviews)
The price is AED 361
AED 397 total
includes taxes & fees
17 Mar - 18 Mar

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.8 out of 10, Excellent, (134 reviews)
The price is AED 291
AED 330 total
includes taxes & fees
10 Mar - 11 Mar

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (852 reviews)
The price is AED 337
AED 374 total
includes taxes & fees
15 Mar - 16 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (64 reviews)
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Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Drury Inn & Suites Greenville
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is AED 226 per night from Apr 1 to Apr 2
AED 226
AED 251 total
1 Apr - 2 Apr
includes taxes & fees
6/10 (561 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
11 properties
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- Wooded Cottage - 3 Mi to Clemson University
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