A bench, a bicycle, and a lake surrounded by trees.

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Check prices for these dates

In two weeks
24 Jul - 26 Jul
In two months
4 Sep - 6 Sep
In three months
2 Oct - 4 Oct
In four months
30 Oct - 1 Nov

Our top choices for Upstate South Carolina villas

Exterior

Grand Southern Elegance near Downtown Pickens

Grand Southern Elegance near Downtown Pickens
Pickens
10.0 out of 10, Exceptional, (1 review)
"This home is perfectly put together for a group to enjoy their time. It combines the history of the house and the new features that make it comfortable. Property is very clean, warm and welcoming. The host was very welcoming and accommodating for us."
United States
John B.
The price is AED 4,297
AED 7,310 total
includes taxes & fees
23 Jul - 24 Jul
Grand Southern Elegance near Downtown Pickens
Terrace/patio

Hartwell Nest • 25 mins to Clemson • Next to Lake

Hartwell Nest • 25 mins to Clemson • Next to Lake
Westminster
The price is AED 397
AED 1,099 total
includes taxes & fees
13 Jul - 14 Jul
Hartwell Nest • 25 mins to Clemson • Next to Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"Amazing stay and staff and nice rooms"
kimberly 2-night trip
Posted less than an hour ago
The Shepherd Hotel Downtown Clemson

Frequently asked questions

How much do villas in Upstate South Carolina cost?
Prices for villas in Upstate South Carolina range between AED 1,099 and AED 6,894 per night. No matter your budget, you're sure to find something that matches your needs on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Why book your villa in Upstate South Carolina with Expedia?
Booking a villa in Upstate South Carolina is as simple as working out your travel dates and selecting an option that meets your needs. Seeking something budget friendly or upmarket, or a stay that also features a pool and free WiFi? Use Expedia's search filters to narrow your results and find your perfect match.
How can I find cheap villas in Upstate South Carolina?
With Expedia's handy filter tool, scoring cheap villas in Upstate South Carolina is a piece of cake. To find stays that give you the most bang for your buck, narrow down your search by budget, amenities and star rating.