A bench, a bicycle, and a lake surrounded by trees.

Search Villas in Upstate South Carolina

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
17 Jul - 19 Jul
In two months
28 Aug - 30 Aug
In three months
25 Sep - 27 Sep
In four months
23 Oct - 25 Oct

Our top choices for Upstate South Carolina villas

Terrace/patio

Hartwell Nest • 25 mins to Clemson • Next to Lake

Hartwell Nest • 25 mins to Clemson • Next to Lake
Westminster
The price is AED 397
AED 1,087 total
includes taxes & fees
5 Jul - 6 Jul
Hartwell Nest • 25 mins to Clemson • Next to Lake
Exterior

2 Mi to Clemson: Central Villa w/ Deck, Near Lakes

2 Mi to Clemson: Central Villa w/ Deck, Near Lakes
Central
9.6 out of 10, Exceptional, (25 reviews)
"We had a great stay! Loved the game room and dog friendly stay. Thanks!"
United States
Matt E.
2 Mi to Clemson: Central Villa w/ Deck, Near Lakes
Exterior

Grand Southern Elegance near Downtown Pickens

Grand Southern Elegance near Downtown Pickens
Pickens
The price is AED 3,967
AED 6,894 total
includes taxes & fees
14 Jul - 15 Jul
Grand Southern Elegance near Downtown Pickens
Exterior

The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access

The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access
Sapphire
10.0 out of 10, Exceptional, (1 review)
"This welcoming home was the perfect size for me and my two small dogs. The location is easily accessible off the main highway, but in a private cul-de-sac which was very quiet and peaceful. The home is tastefully decorated and very comfortable. Perfect get-away for a small family or two couples. I appreciate Sarah providing all the information I needed and checking in with me during my stay. "
United States
William P.
The price is AED 1,499
AED 2,648 total
includes taxes & fees
5 Jul - 6 Jul
The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Upstate South Carolina Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"Excellent location and the staff was fantastic. Thank you Monica!"
JENNIFER 1-night trip
Posted 4 hours ago
The Shepherd Hotel Downtown Clemson

Frequently asked questions

How much do villas in Upstate South Carolina cost?
Prices for villas in Upstate South Carolina range between AED 1,257 and AED 7,098 per night. No matter your budget, you're sure to find something that matches your needs on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Why book your villa in Upstate South Carolina with Expedia?
Booking a villa in Upstate South Carolina is as simple as working out your travel dates and selecting an option that meets your needs. Seeking something budget friendly or upmarket, or a stay that also features a pool and free WiFi? Use Expedia's search filters to narrow your results and find your perfect match.
How can I find cheap villas in Upstate South Carolina?
With Expedia's handy filter tool, scoring cheap villas in Upstate South Carolina is a piece of cake. To find stays that give you the most bang for your buck, narrow down your search by budget, amenities and star rating.