Upstate South Carolina Vacations

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

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Upstate South Carolina Hotel Deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
The price is AED 364 per night from Mar 12 to Mar 13
AED 364
AED 400 total
12 Mar - 13 Mar
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
Excellent breakfast n ambience

Reviewed on 3 February 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is AED 1,025 per night from Feb 22 to Feb 23
AED 1,025
AED 1,158 total
22 Feb - 23 Feb
includes taxes & fees
9.4/10 Exceptional! (442 reviews)
I would have given it five stars, but the only reason I didn’t is because breakfast they only serve bacon and pork sausage. I wish they would have had turkey sausage, vegan sausage or beef as well to choose from but the food is delicious.!!!!

Reviewed on 28 January 2026

Grand Bohemian Lodge Greenville, Autograph Collection
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Wooded Cottage - 3 Mi to Clemson University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Upstate South Carolina

Frequently asked questions

How do I find cheap flights to Upstate South Carolina that have flexible change policies?
By using our smart "No change fee" filter, that's how. Just type in your origin, destination and travel dates, click the "Search" button, then tick the checkbox directly under the "Flexible change policies" heading (left-hand side of your screen). Expedia makes it a snap to find flexible and affordable tickets to Upstate South Carolina.
Which airlines fly to Upstate South Carolina?
A range of airlines fly to airports in or close to Upstate South Carolina. Your next big adventure is a few clicks away with these top carriers:

  • American Airlines - 18,171 flights to or near Upstate South Carolina each month, including 17,199 flights to Charlotte-Douglas Intl. Airport (CLT) and 672 to Greenville-Spartanburg Intl. Airport (GSP) per month.
  • Delta - 1,456 flights to or near Upstate South Carolina each month, including 915 flights to Charlotte-Douglas Intl. Airport (CLT) and 359 to Greenville-Spartanburg Intl. Airport (GSP) per month.
  • United Airlines - 777 flights to or near Upstate South Carolina each month, including 451 flights to Charlotte-Douglas Intl. Airport (CLT) and 234 to Greenville-Spartanburg Intl. Airport (GSP) per month.

How can I find cheap tickets to Upstate South Carolina?
An effective strategy for picking up cheap tickets is to be flexible with your dates. Start by searching for your flight to Upstate South Carolina, then click on the "flexible dates" box to compare prices for nearby days. Another good tip? Book ahead of time. To give you an idea of fares, was the best price for a flight to Upstate South Carolina in the last seven days.
How much is a flight to Upstate South Carolina?
In the last seven days, return flights to Upstate South Carolina sold from just and reached a maximum price of . For one-way trips out of (), the lowest amount paid during this same period was just .
What are the most popular airports to fly into in Upstate South Carolina?
Your budget, departure point and your preferred carrier will help determine which of these popular Upstate South Carolina airports you'll touch down at:

  • Charlotte-Douglas Intl. Airport (CLT) - 19,602 flights per month.
  • Greenville-Spartanburg Intl. Airport (GSP) - 1,418 flights per month.
  • Asheville Regional Airport (AVL) - 754 flights per month.

When is the cheapest time to fly to Upstate South Carolina?
Consider leaving early in the week to get the best airfare to Upstate South Carolina. Tuesday is routinely the most affordable day to take off, with Monday a close second. Saturday typically has the most expensive fares. This is because many people prefer to start their vacation on a weekend.
How much is a plane ticket to Upstate South Carolina?
In the last seven days, flights to Upstate South Carolina cost between and . Prices depend on multiple things, particularly the time of departure, carrier, cabin class and when you make your booking.
What months are the cheapest to book a flight to Upstate South Carolina?
February is an excellent month to score a fantastic deal to Upstate South Carolina. Keep in mind that the costliest time to make a purchase in the USA isn't the middle of summer, but the festive month of December.
How long is a flight to Upstate South Carolina?
Whether or not you'll have time to watch one movie or two depends on where you're flying from in the U.S. To give you an idea of what to expect, here are the average flight times for three busy domestic routes to Upstate South Carolina:

  • New York, NY (LGA-LaGuardia) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 13 minutes
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 1 hour and 19 minutes
  • Chicago, IL (ORD-O'Hare Intl.) to Charlotte-Douglas Intl. Airport (CLT) - 2 hours and 6 minutes

What are the best things to do in Upstate South Carolina?

  • Overflowing with culture, energy and excitement, Greenville is a great base to begin your Upstate South Carolina trip. Take a look at popular attractions like Falls Park on the Reedy, hit up the shops or eat and drink your way around some of this location's inviting restaurants. The choice is yours!
  • When it comes to deciding the activities for your trip, take into account that Greenville has a humid subtropical climate. It's a wise idea to check the weather conditions before you jet off so you have a clearer idea of what to expect.
  • Make Pelzer the next place you head to. It's about 24 kilometers to the south of Greenville and where you'll discover City Scape Winery, one of the city's top tourist sights.

What is the best time to go to Upstate South Carolina?
Anytime is an excellent time to see Greenville, Upstate South Carolina's main city, but May, July and August are when it's at its liveliest. Summer kicks off June 20 inches the USA and is a top time to travel if you enjoy the outdoors. Temperatures range from 20ºC (68ºF) to 32ºC (90ºF) during this season.