The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Check prices for these dates

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for West Main Historic District hotels

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

1. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,387 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is AED 479
AED 563 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
A modern lobby with a central seating area, a reception desk, and a large screen.

2. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,837 reviews)
"Great buffet breakfast"
United States
Lisa
The price is AED 342
AED 402 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Louisville Downtown by IHG
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

3. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is AED 524
AED 616 total
includes taxes & fees
26 Nov - 27 Nov
Seelbach Hilton Louisville Downtown
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

4. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (176 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is AED 479
AED 563 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
"Good clean rooms."
United States
Paul
The price is AED 350
AED 412 total
includes taxes & fees
9 Nov - 10 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

6. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,218 reviews)
"Nice location"
United States
Brian
The price is AED 483
AED 568 total
includes taxes & fees
9 Nov - 10 Nov
Omni Louisville Hotel
A classical gold statue in front of a multi-story building with large windows and a brick facade.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is AED 559
AED 676 total
includes taxes & fees
24 Nov - 25 Nov
21c Museum Hotel Louisville
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

8. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place"
United States
MILTON
The price is AED 430
AED 506 total
includes taxes & fees
22 Nov - 23 Nov
Louisville Marriott Downtown
A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

9. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,000 reviews)
"Room was very clean, great hospitality, our balcony was right across the street from the yum center where we saw Dave Chappelle. Will definitely stay again."
United States
Jessica
The price is AED 364
AED 429 total
includes taxes & fees
29 Nov - 30 Nov
Courtyard by Marriott Louisville Downtown
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

10. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,001 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is AED 417
AED 490 total
includes taxes & fees
18 Nov - 19 Nov
Aloft by Marriott Louisville Downtown
An indoor swimming pool with clear blue water, surrounded by lounge chairs and large windows.

11. Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,002 reviews)
"Room was clean, able to reach out to the staff in a timely manner if you needed anything, and great location."
United States
Brandon
The price is AED 296
AED 348 total
includes taxes & fees
28 Nov - 29 Nov
Hampton Inn Louisville Downtown
A lobby with a reception desk, seating area, and a fireplace.

12. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,004 reviews)
"Great Location"
Canada
Eric
The price is AED 340
AED 400 total
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites by Marriott Louisville Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

13. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is AED 459
AED 540 total
includes taxes & fees
23 Nov - 24 Nov
Hyatt Regency Louisville
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,018 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is AED 350
AED 411 total
includes taxes & fees
24 Nov - 25 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
A balcony with a view of a river, a bridge, and a cityscape.

15. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,446 reviews)
"Beautiful hotel and great location!"
United States
ERIC
The price is AED 500
AED 588 total
includes taxes & fees
15 Nov - 16 Nov
Galt House Hotel Trademark Collection by Wyndham
An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (824 reviews)
"Breakfast was very good with lots of options."
United States
Cheryl
The price is AED 371
AED 436 total
includes taxes & fees
30 Nov - 1 Dec
Towneplace Suites By Marriott Louisville Downtown
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

17. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,006 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is AED 572
AED 673 total
includes taxes & fees
15 Nov - 16 Nov
The Grady
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

18. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (517 reviews)
"Very clean / helpful and accommodating staff / excellent restaurant"
United States
Kimberly
The price is AED 740
AED 871 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
A hotel room with two beds, a TV, and a desk.

19. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,000 reviews)
"Great location. Clean rooms. Nice staff."
United States
Kim
The price is AED 372
AED 437 total
includes taxes & fees
22 Nov - 23 Nov
SpringHill Suites by Marriott Louisville Downtown
A spacious lobby with leather sofas, round tables, and ottomans, featuring large windows and modern lighting fixtures.

20. Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay!"
United States
Kooper
The price is AED 378
AED 445 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
517 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,001 reviews
View
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
9.4
Exceptional
176 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,001 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,006 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top West Main Historic District Hotel Reviews

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

8/10 Good
"Staff was friendly. Room was clean. Dinner on the rooftop bar was excellent."
Carrie 1-night trip
Posted 1 hour ago
Hilton Garden Inn Louisville Downtown

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.