A conservatory with a glass dome, surrounded by a garden with pink flowers and benches.

West Seneca Vacation Rentals

Q: What are some of the best vacation home rentals that West Seneca has to offer?

HTR Niagara : This vacation home rental outside of West Seneca is on the riverwalk and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

Where to?

Dates

November 2026

December 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for West Seneca vacation rentals

A modern living room with a sofa, a coffee table, and a TV. There is a mirror on the wall and a door leading to another room.

1. Spacious 3BR Home | Recently Remodeled | Private Yard & Parking

West Seneca

Sean

AED 1,132 total

includes taxes & fees

11 Nov - 12 Nov

A modern living room with a sofa, armchair, and coffee table. There is a flat-screen TV mounted on the wall.

2. Your Cozy Home Away From Home king bed, parking

West Seneca

Jay M.

AED 1,036 total

includes taxes & fees

16 Nov - 17 Nov

A building entrance with a covered walkway, stone pillars, and a glass door.

3. ADA Studio in Buffalo w/ Kitchen & Bathtub

West Seneca

AED 1,028 total

includes taxes & fees

12 Nov - 13 Nov

A living room with a fireplace, a television, and a sofa.

4. Big new house with huge parking

West Seneca

Andy

AED 2,342 total

includes taxes & fees

12 Nov - 13 Nov

5. Accessible 1-BR Suite, 2 Doubles, Sleeps 5

West Seneca

AED 1,186 total

includes taxes & fees

15 Nov - 16 Nov

6. Convenient Queen Studio w/ Full Kitchen Nr Buffalo

West Seneca

AED 1,028 total

includes taxes & fees

12 Nov - 13 Nov

7. King Bed 1-BR Suite w/ Kitchen Near Buffalo

West Seneca

AED 1,132 total

includes taxes & fees

15 Nov - 16 Nov

8. Family 1-BR Suite, 2 Doubles Near Buffalo

West Seneca

Korie P.

AED 1,186 total

includes taxes & fees

15 Nov - 16 Nov

9. Accessible Suite w/ Kitchen, Breakfast, & Pool!

West Seneca

AED 1,803 total

includes taxes & fees

15 Nov - 16 Nov

10. Largest 2-BR Suite, Sleeps 7 Near Buffalo

West Seneca

AED 1,771 total

includes taxes & fees

16 Nov - 17 Nov

A spacious living room with a leather sofa, teal armchairs, a glass coffee table, and a television.

11. The Victorian on South Park • Sleeps 6

Triangle

Sara S.

AED 819 total

includes taxes & fees

16 Nov - 17 Nov

A living room with a sofa set, a coffee table, a TV, a lamp, and a fireplace.

12. Nice big house with parking, fenced yard

Buffalo

JOSEPH Z.

AED 1,194 total

includes taxes & fees

11 Nov - 12 Nov

A living room with a grey sofa, a coffee table, and a television. There is a window with curtains, a painting on the wall, and a vase with flowers on a side table.

13. Cozy 3BR Lower Unit home in South Buffalo Near Downtown

South Park

Maddie M.

AED 1,024 total

includes taxes & fees

1 Dec - 2 Dec

A corner room with a curved wall, large windows, and a wooden floor.

14. Cozy 3-bedroom house in charming Buffalo with WiFi, AC

Kaisertown

Cristian

AED 839 total

includes taxes & fees

6 Dec - 7 Dec

A bedroom with a bed featuring Buffalo Bills branding, a framed picture of a football player, and a wall clock.

15. Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Orchard Park

Danny Dreaden J.

AED 999 total

includes taxes & fees

15 Nov - 16 Nov

A dining room with a black table, blue upholstered chairs, and a matching bench.

16. 420 Friendly 3 bedroom upstairs apartment. Street parking only.

Seneca

MacKenzie G.

AED 742 total

includes taxes & fees

11 Nov - 12 Nov

A living room with a flat-screen TV displaying a streaming service interface, a decorative wall piece, a hanging plant, and a small shelf with toys and books.

17. Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Blasdell

Jan E.

AED 1,012 total

includes taxes & fees

11 Nov - 12 Nov

A covered outdoor patio with a fire feature, seating, and a table.

18. Spacious/Comfy/Private Home near Buffalo/Bills/Airport/Niagara Falls

Depew

Jodhan B.

AED 1,941 total

includes taxes & fees

12 Nov - 13 Nov

A kitchen with a marble countertop, a coffee maker, a kettle, and a drawer with cooking utensils.

19. Nice and cozy house with king bed fenced yard

Broadway - Fillmore

Pearline M.

AED 976 total

includes taxes & fees

30 Nov - 1 Dec

A modern living room with a sofa, a dining table with chairs, a kitchen area with cabinets and appliances, and a ceiling fan.

20. Nice house with king bed 25min to Niagara falls

Broadway - Fillmore

Alexander

AED 976 total

includes taxes & fees

30 Nov - 1 Dec

View all properties

Find vacation rentals that suit your style

Top West Seneca Hotel Reviews

A building entrance with a brick facade, a covered walkway, and a bench.

Staybridge Suites West Seneca by IHG

Buffalo

10/10 Excellent

Staybridge Suites exceeded all my expectations, and that is saying a lot for me. Not only was the room clean and comfortable, the towels were a good size, four pillows per bed, and a fully stocked kitchenette for our suite. I really liked that there was a tub in one bathroom and a step in shower in the other. That worked really well for our group. Highway noise was not an issue. There was a wide variety of breakfast items, hot and cold. The evening socials on Tuesday Wednesday and Thursday were...

Anonymous traveler

An indoor swimming pool with clear water, a lifebuoy, and a pool ladder.

Hampton Inn Buffalo South/I-90

Buffalo

10/10 Excellent

Mary

A Country Inn & Suites hotel with a prominent entrance, multiple floors, and a well-lit facade.

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Buffalo

10/10 Excellent

Holly

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

InnBuffalo off Elmwood

Elmwood Village

10/10 Excellent

Lerran

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

The Edward Hotel

Elmwood Village

10/10 Excellent

Dawn

A buffet setup with various food items and utensils.

Salvatores Grand Hotel

Buffalo

10/10 Excellent

This is a beautiful hotel. Our king suite was so very nice. Having a top rated restaurant right there was amazing and the breakfast next morning was delicious and well stocked. I can't wait to visit again and take some other family members. My husband said he would drive the 3 hours from where we live just to stay at the hotel and dine at Russells. That is saying something because he is not a traveler. The Christmas decorations were so very festive. We were there for a wake and memorial service...

Dawn

A hotel with a prominent entrance, a clock tower, and the name "REIKART HOUSE" displayed above the entrance.

Reikart House, Buffalo, a Tribute Portfolio Hotel

Buffalo

10/10 Excellent

We were so pleasantly surprised when we arrived at the hotel. We travel to Buffalo often, family and our daughter is in college there. We have stayed in many hotels in the area but none were as charming, beautifully designed, clean, and had a staff that was available for anything you needed. The lobby is like being in someones beautifully decorated living room. Our room was lovely with a very comfortable bed and a small living room wtth a pull out sofa. Thanks for the candy when we arrived...

Anonymous traveler

A house with a covered porch, a pathway leading to the entrance, and a well-maintained garden.

Asa Ransom House

Clarence

10/10 Excellent

Jiasui

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo

10/10 Excellent

Anonymous traveler

A modern hotel lobby with a reception desk, seating areas, and a television screen.

Hampton Inn East Aurora

East Aurora

10/10 Excellent

Mary

A compact hotel room with a bed, a small kitchenette, a dining area with a table and stools, and a living area with a sofa.

The Fields of Eden Inn

Eden

10/10 Excellent

John

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

Curtiss Hotel, an Ascend Collection Hotel

Downtown Buffalo

10/10 Excellent

Eric

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

The Mansion On Delaware Ave

Downtown Buffalo

10/10 Excellent

Evan

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

Buffalo

10/10 Excellent

Marc

Hampton Inn Buffalo - Amherst, NY

Buffalo

10/10 Excellent

Sarah

An outdoor patio with a fire pit, seating, and string lights.

Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

10/10 Excellent

Pam

A modern hotel lobby with a bar area, seating, and a large TV screen.

Residence Inn by Marriott Buffalo Downtown

Downtown Buffalo

10/10 Excellent

Anonymous traveler

Frequently Asked Questions

Can I find vacation rentals in West Seneca?

Yes, we give you a choice of vacation rentals in West Seneca close to Charles E. Burchfield Nature and Art Center, or you can choose a secluded option if you're looking for extra privacy while you relax. Tourists like the array of shops and top-notch restaurants in West Seneca. Allow lots of time to check out the waterfalls and coffeehouses during your visit.

What are some of the best vacation home rentals that West Seneca has to offer?

HTR Niagara: This vacation home rental outside of West Seneca is on the riverwalk and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals are there in West Seneca?

With 9 Expedia vacation rentals, you're sure to find just the right place for your West Seneca stay.

What’s there to see and do in West Seneca?

Charles E. Burchfield Nature and Art Center and Cazenovia Park are a couple of lovely local spots to get outside and enjoy nature. In the larger area, you’ll find Southgate Plaza and Highmark Stadium.

What’s a vacation rental in West Seneca like?

Vacation rentals are private properties where you can stay for short or long periods in West Seneca. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can provide a sense of safety away from public hotel elevators and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.

West Seneca Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for West Seneca vacation rentals

1. Spacious 3BR Home | Recently Remodeled | Private Yard & Parking

2. Your Cozy Home Away From Home king bed, parking

3. ADA Studio in Buffalo w/ Kitchen & Bathtub

4. Big new house with huge parking

5. Accessible 1-BR Suite, 2 Doubles, Sleeps 5

6. Convenient Queen Studio w/ Full Kitchen Nr Buffalo

7. King Bed 1-BR Suite w/ Kitchen Near Buffalo

8. Family 1-BR Suite, 2 Doubles Near Buffalo

9. Accessible Suite w/ Kitchen, Breakfast, & Pool!

10. Largest 2-BR Suite, Sleeps 7 Near Buffalo

11. The Victorian on South Park • Sleeps 6

12. Nice big house with parking, fenced yard

13. Cozy 3BR Lower Unit home in South Buffalo Near Downtown

14. Cozy 3-bedroom house in charming Buffalo with WiFi, AC

15. Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

16. 420 Friendly 3 bedroom upstairs apartment. Street parking only.

17. Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

18. Spacious/Comfy/Private Home near Buffalo/Bills/Airport/Niagara Falls

19. Nice and cozy house with king bed fenced yard

20. Nice house with king bed 25min to Niagara falls

Find vacation rentals that suit your style

Top West Seneca Hotel Reviews

Staybridge Suites West Seneca by IHG

10/10 Excellent

Frequently Asked Questions

Can I find vacation rentals in West Seneca?

What are some of the best vacation home rentals that West Seneca has to offer?

How many vacation rentals are there in West Seneca?

What’s there to see and do in West Seneca?

What’s a vacation rental in West Seneca like?