A red train on tracks, palm trees, and modern buildings.

Find 4 Star Hotels in Central San Diego, CA from AED 540

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego 4 Star Hotels

Tonight
1 Oct - 2 Oct
Tomorrow
2 Oct - 3 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Central San Diego 4-star hotels

An outdoor lounge area with seating, a fire feature, and a pool in the background.
A stone wall with a neon sign that reads "Tom & Jerry."
A hotel with a large pool surrounded by lounge chairs and umbrellas, palm trees, and a well-lit building facade.
A spacious lobby with a bar area, leather armchairs, and a reception desk.

1. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Sol
AED 889
AED 1,149 total
includes taxes & fees
5 Oct - 6 Oct
Town and Country San Diego
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Bryanna
AED 984
AED 1,131 total
includes taxes & fees
4 Oct - 5 Oct
Lafayette Hotel & Club
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A poolside area with a concrete pool, lounge chairs, and a wooden deck.
A spacious lobby with a central seating area, a staircase, and a view of the hallway leading to the entrance.
A modern dining area with a large table, chairs, and hanging plants.

3. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Paul
AED 540
AED 621 total
includes taxes & fees
15 Oct - 16 Oct
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a tall building in the background.
A spacious indoor lounge area with a central fire feature, multiple seating arrangements, and a bar area.
A spacious gym with various exercise equipment, large windows, and a wooden floor.

4. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Debra L
AED 676
AED 777 total
includes taxes & fees
31 Oct - 1 Nov
San Diego Marriott La Jolla
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.

5. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
United States
Mary
AED 509
AED 585 total
includes taxes & fees
22 Oct - 23 Oct
Hilton San Diego Mission Valley
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A swimming pool with a visible water filtration system and a tiled edge.
A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.

6. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Virginia
AED 621
AED 819 total
includes taxes & fees
31 Oct - 1 Nov
Embassy Suites by Hilton San Diego La Jolla
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A pathway leading to a building labeled "LEGACY Hotel."
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

7. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
AED 658
AED 756 total
includes taxes & fees
4 Oct - 5 Oct
Legacy Resort Hotel & Spa
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A poolside area with a fire pit, lounge chairs, and a pool.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a view through an open door.
A modern hotel with a flat roof, large windows, and a sign reading "DOLLYWOOD HOTEL".

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
AED 470
AED 540 total
includes taxes & fees
4 Oct - 5 Oct
DoubleTree by Hilton San Diego - Hotel Circle
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.
A modern lobby with a round table and four chairs, a reception desk, and a large window.
A modern outdoor seating area with a wooden wall, a hanging chair, and a large potted plant.

9. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
Laura
AED 584
AED 671 total
includes taxes & fees
25 Oct - 26 Oct
San Diego Marriott Mission Valley
A rooftop pool area with lounge chairs, a fire pit, and string lights.
A modern bar area with a long counter, multiple seating options, and pendant lighting.
A spacious lobby with high ceilings, a central staircase, and bookshelves along the walls.
A hotel room with a large bed, a sofa, a round table, and a view of buildings through the windows.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
Mardo
AED 746
AED 977 total
includes taxes & fees
23 Oct - 24 Oct
Hyatt Regency La Jolla
An outdoor patio with tables and chairs, string lights, and umbrellas.
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.
Property amenity
A modern room with a glass dining table, two bar stools, a sofa, and a TV stand with decorative items.

11. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Leanna
AED 657
AED 756 total
includes taxes & fees
5 Oct - 6 Oct
Sheraton Mission Valley San Diego Hotel
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
A modern interior with concrete walls, wooden beams, and a central planter with plants.
A modern bedroom with a large bed, a nightstand, a wall-mounted lamp, and a window with curtains.
An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.

12. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Jesus
AED 426
AED 605 total
includes taxes & fees
26 Oct - 27 Oct
City24 Hotel Little Italy Mission Hills
BBQ/picnic area
Room
Breakfast area
Room

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A coastal landscape with red rock formations and a view of the ocean.

Top Central San Diego Hotel Reviews

San Diego Marriott La Jolla

San Diego Marriott La Jolla

10/10 Excellent
"Loved seeing the Thunderbirds flying around on Saturday!"
Becky 1-night trip
Posted 2 hours ago
San Diego Marriott La Jolla
Town and Country San Diego

Town and Country San Diego

10/10 Excellent
"Great hotel for the price. Our kids enjoyed it."
Alberto 3-night trip
Posted 13 hours ago
Town and Country San Diego
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

10/10 Excellent
"It was top tier all around."
Jesus 2-night trip
Posted 22 hours ago
Hilton San Diego Mission Valley

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price from AED 540
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to search for your next getaway in Central San Diego where everything is taken care of, from your room to your meals, activities and entertainment. We can also help you find standard 4-star stays in and around this destination.

Explore a world of travel with Expedia