Find 5 Star Hotels in Florida Keys from AED 1,257

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Check availability on Florida Keys 5 Star Hotels

Tonight
6 May - 7 May
Tomorrow
7 May - 8 May
This weekend
8 May - 10 May
Next weekend
15 May - 17 May

Our top choices for Florida Keys 5-star hotels

On the beach, sun loungers, beach umbrellas, beach towels

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
5.0 star property
Marathon
9.2 out of 10, Wonderful, (1,143 reviews)
"Great location and amazing views"
United States
Imtiaz
The price is AED 1,115
AED 1,486 total
includes taxes & fees
26 May - 27 May
Isla Bella Beach Resort & Spa
Balcony

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,324 reviews)
"Such a nice resort with so much to do! We ended up extended our stay at this hotel because we loved it here at cheeca so much! "
United States
Zachary
The price is AED 887
AED 1,266 total
includes taxes & fees
21 May - 22 May
Cheeca Lodge & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL
The price is AED 889 per night from May 26 to May 27
AED 889
AED 1,257 total
26 May - 27 May
includes taxes & fees
8.2/10 Very Good! (1,011 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys

Top Florida Keys Hotel Reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"A great resort. Lovely grounds. Gym was lacking"
Brad W 5-night trip
Posted 2 hours ago
Isla Bella Beach Resort & Spa
Cheeca Lodge & Spa

Cheeca Lodge & Spa

6/10 Okay
"Beautiful setting and excellent beach areas created perfect setting for an outstanding wedding weekend we attended. Unfortunately the rooms and common areas appear dated. Friends traveling with us had a large HVAC vent fall near them while walking into their bathroom. Staff members were not particularly friendly in the hotel and restaurants. Housekeepers and a “doorman”pounded on our door on two different occasions despite the fact that our do not disturb sign was on the door handle. Overall very disappointed for the price. "
Ray 2-night trip
Posted 2 hours ago
Cheeca Lodge & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from AED 1,257

What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia's filters are the best way to narrow down what you're looking for. Select "5-star" and "All inclusive" to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.

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