Find 5 Star Hotels in Otay Mesa West, CA from AED 498

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Check availability on Otay Mesa West 5 Star Hotels

Our top choices for Otay Mesa West 5-star hotels

3 restaurants, breakfast, lunch, dinner served; seafood
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1004)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is AED 937
AED 1,279 total
includes taxes & fees
4 Jan - 5 January 2026
Pendry San Diego
View from property
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego
5.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1004)
"I loved my stay here ! I would definitely stay here again . The staff were pleasant and welcoming. The amenities were great ! The only complaint I have is I wish parking was included in our stay if you’re staying at the hotel as a guest "
United States
Vanessa
The price is AED 1,008
AED 1,169 total
includes taxes & fees
5 Jan - 6 January 2026
The US Grant, a Luxury Collection Hotel, San Diego
View from room
Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts

Shore House at The Del, LXR Hotels & Resorts
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (113)
"What a beautiful place. We had the best room with an incredible view of the ocean. The staff was very friendly and helpful. We will definitely return."
United States
Charles
The price is AED 2,108
AED 2,524 total
includes taxes & fees
20 Dec - 21 Dec
Shore House at The Del, LXR Hotels & Resorts
Oceanfront Horizon Cottage | Living area | 55-inch Smart TV with cable channels, fireplace, Netflix
Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (121)
"Great experience! Wonderful staff"
Canada
Leena
The price is AED 2,710
AED 3,170 total
includes taxes & fees
3 Jan - 4 January 2026
Beach Village at The Del, LXR Hotels & Resorts
Interior
The Bower Coronado

The Bower Coronado

The Bower Coronado
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (150)
"Great place. Great rooftop bar. "
United States
Michael
The price is AED 757
AED 1,016 total
includes taxes & fees
15 Dec - 16 Dec
The Bower Coronado
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa West.
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

1500 Orange Ave Coronado CA
The price is AED 1,246 per night from Jan 4 to Jan 5
AED 1,246
AED 1,587 total
4 Jan - 5 January 2026
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa West Hotel Reviews

Pendry San Diego

Pendry San Diego

10/10 Excellent
"Nice😁"
Juston 3-night trip
Posted 7 days ago
Pendry San Diego

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Otay Mesa West?
You'll find a variety of pricing options for 5-star hotels in Otay Mesa West on Expedia. How much you'll pay will depend on when you travel, length of stay and other factors. Compare all of the available accommodations for your preferred dates and use our pricing and other filters to discover the perfect upscale stay.

  • Search for the lowest price per night from AED 498

What makes a hotel 5 stars in Otay Mesa West?
In Otay Mesa West, a hotel needs to provide a certain number of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can expect things like in-room massages, concierge services and nightly turn-down services. Some may even offer special touches like a welcome gift.
Are there any 5-star all-inclusive resorts in Otay Mesa West?
Use our filters to find a high-end getaway in Otay Mesa West where most of what you need is included. After your initial search, refine your results for accommodations that have 5 stars and are categorized as "All inclusive." The main thing on the to-do list at these stays? Pure enjoyment and indulgence.

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