Antofagasta Region Vacations

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Top destinations in Antofagasta Region

A narrow dirt road lined with buildings and trees, with people walking and a stroller visible.

San Pedro de Atacama

San Pedro de Atacama
A desert landscape with sparse vegetation and distant snow-capped mountains.

María Elena

María Elena

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

Toconao 460 San Pedro de Atacama Antofagasta
Fully refundableReserve now, pay when you stay
AED 415
AED 415 total
13 Aug - 14 Aug
8.2/10 Very Good! (400 reviews)
"Staff very helpful and friendly, although no English. Happy to converse using translation tools. Swimming pool was closed due to it being winter, which I didn’t reslise when I booked. A couple of times there was no water, no electricity and no wifi, but staff worked to resolve the issue. Breakfast ..."

Reviewed on 18 July 2026

Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas

Hotel La Casa de Don Tomas

Calle Tocopilla Sitio 18 San Pedro de Atacama
Fully refundableReserve now, pay when you stay
AED 771
AED 771 total
13 Aug - 14 Aug
9.2/10 Wonderful! (432 reviews)
"Overall a nice stay at El Refugio La Casa de Don Tomas. The room is big and quiet and the location is roughly 10 minutes away from city center. Keep in mind that the rooms have no air conditioning so they get quite stuffy during the day. The breakfast is quite disappointing as it’s very basic. The ..."

Reviewed on 10 August 2026

Hotel La Casa de Don Tomas
Noi Casa Atacama

Noi Casa Atacama

Tocopilla E-8 San Pedro de Atacama Antofagasta
AED 864
AED 864 total
16 Aug - 17 Aug
Noi Casa Atacama
See all 297 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Antofagasta Region attractions

A desert landscape with layered rock formations and sand dunes.

Valley of the Moon

9.2/10 (244 reviews)
Explore the great outdoors at Valley of the Moon, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.
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A rugged mountain with reddish-brown rock formations and sparse vegetation under a clear blue sky.

Arco Iris Valley

9.0/10 (55 reviews)
Explore the great outdoors at Arco Iris Valley, a lovely green space in San Pedro de Atacama. You can seek out the local tours while in the area.
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Plaza de San Pedro de Atacama

8.4/10 (195 reviews)
You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.
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Cerro Paranal Observatory

8.6/10 (4 reviews)
Commune with nature and explore the great outdoors at Cerro Paranal Observatory during your travels in Antofagasta. Amble around the area's seaside or visit its shops.
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San Pedro Church

8.6/10 (64 reviews)
San Pedro Church is just one of the places to see in San Pedro de Atacama, so why not enjoy the other things to explore during your travels? You can seek out the local tours in this quaint area.
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Mall Plaza Calama

8.8/10 (9 reviews)
During your trip to Calama, you can enjoy retail therapy at Mall Plaza Calama. Discover the area's desert landscape and casinos.
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Piedra del Coyote Overlook

8.8/10 (61 reviews)
Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.
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Tulor Archaeological Site

8.4/10 (6 reviews)
You can find out about the history of San Pedro de Atacama with a trip to Tulor Archaeological Site. You can seek out the local tours in this quaint area.
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