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Our top choices for Cairo, IL (CIR-Cairo Regional) hotels

Quality Inn Cairo I-57
Quality Inn Cairo I-573.4 km from Cairo, IL (CIR-Cairo Regional)
6.4 out of 10, (289 reviews)
The price is AED 251
AED 278 total
includes taxes & fees
11 Jul - 12 Jul

Eagle Inn Charleston
Eagle Inn Charleston17.2 km from Cairo, IL (CIR-Cairo Regional)
6.6 out of 10, (106 reviews)
The price is AED 263
AED 291 total
includes taxes & fees
27 Jun - 28 Jun

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO18 km from Cairo, IL (CIR-Cairo Regional)
6.6 out of 10, (642 reviews)
The price is AED 219
AED 243 total
includes taxes & fees
12 Jul - 13 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Cairo Regional Hotel Reviews

Best Western Plus Sikeston I-55
8/10 Good
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Hotels near popular Cairo Attractions
Hotel options around Cairo Regional
- Drury Inn & Suites Sikeston, MO
- Fabulous cabin with AC in charming Tamms
- Beautiful Cabin Retreat
- Best Western Plus Sikeston I-55
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Super 8 by Wyndham Sikeston/Miner Area
- The Riverview
- Country Yard Inn and Suite
- Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
- Comfort Inn & Suites Sikeston I-55
- Charming cottage overlooking Lake Acre
- Charming Home just minutes from Interstate and Mall
- Courtyard by Marriott Cape Girardeau Downtown
- Quiet Country Stay: Modern Home Near Paducah
- Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
- Serenity South -- Gardens, River-Views, and Refreshing Space
- Little Blue Cottage on Spanish
- Holiday Inn Express & Suites Sikeston Southwest by IHG
















